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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for IRF2_STAT2_IRF8_IRF1
Z-value: 7.52
Motif logo
Transcription factors associated with IRF2_STAT2_IRF8_IRF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
IRF2
|
ENSG00000168310.6 | interferon regulatory factor 2 |
|
STAT2
|
ENSG00000170581.9 | signal transducer and activator of transcription 2 |
|
IRF8
|
ENSG00000140968.6 | interferon regulatory factor 8 |
|
IRF1
|
ENSG00000125347.9 | interferon regulatory factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| STAT2 | hg19_v2_chr12_-_56753858_56753930 | 0.96 | 4.0e-11 | Click! |
| IRF8 | hg19_v2_chr16_+_85942594_85942635 | -0.59 | 5.7e-03 | Click! |
| IRF2 | hg19_v2_chr4_-_185395672_185395734 | 0.57 | 8.2e-03 | Click! |
| IRF1 | hg19_v2_chr5_-_131826457_131826514 | 0.46 | 3.9e-02 | Click! |
Activity profile of IRF2_STAT2_IRF8_IRF1 motif
Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of IRF2_STAT2_IRF8_IRF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.8 | 27.3 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 5.2 | 20.9 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 5.0 | 54.7 | GO:0018377 | protein myristoylation(GO:0018377) |
| 4.7 | 14.2 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253) |
| 4.2 | 25.3 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 4.1 | 16.5 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 4.1 | 20.5 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 3.9 | 11.8 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 3.4 | 20.3 | GO:0034165 | positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) |
| 3.2 | 38.9 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 3.0 | 45.6 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 2.7 | 10.8 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 2.4 | 9.5 | GO:0002428 | antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) |
| 2.2 | 6.7 | GO:1902173 | negative regulation of keratinocyte apoptotic process(GO:1902173) |
| 2.2 | 45.7 | GO:0003373 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 2.1 | 21.2 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 2.0 | 9.9 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 1.9 | 15.5 | GO:0030578 | PML body organization(GO:0030578) |
| 1.9 | 5.8 | GO:0002519 | natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 1.9 | 7.5 | GO:0036269 | swimming behavior(GO:0036269) |
| 1.8 | 1.8 | GO:0002859 | negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) |
| 1.7 | 10.1 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 1.7 | 11.8 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 1.6 | 26.4 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 1.6 | 13.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.5 | 3.1 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 1.4 | 8.5 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 1.4 | 11.2 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 1.4 | 1.4 | GO:0002590 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) |
| 1.3 | 3.8 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 1.2 | 9.5 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.2 | 3.5 | GO:0048633 | negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 1.2 | 1.2 | GO:0060545 | positive regulation of necroptotic process(GO:0060545) |
| 1.1 | 6.9 | GO:0030421 | defecation(GO:0030421) |
| 1.1 | 8.7 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 1.1 | 4.3 | GO:0090086 | negative regulation of protein deubiquitination(GO:0090086) |
| 1.0 | 12.3 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 1.0 | 3.0 | GO:0021776 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 1.0 | 4.0 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.9 | 10.4 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.9 | 4.7 | GO:0021557 | optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623) |
| 0.9 | 10.3 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) |
| 0.9 | 28.5 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 0.9 | 13.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.8 | 2.5 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 0.8 | 55.7 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
| 0.8 | 4.0 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.7 | 18.2 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.7 | 16.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.7 | 4.9 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.6 | 1.9 | GO:0060129 | regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
| 0.6 | 1.9 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.6 | 2.6 | GO:0070895 | transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895) |
| 0.6 | 30.0 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.6 | 1.9 | GO:0048627 | myoblast development(GO:0048627) |
| 0.6 | 7.5 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.6 | 1.8 | GO:1904596 | regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204) |
| 0.6 | 2.8 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.5 | 11.5 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.5 | 5.9 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.5 | 10.4 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.5 | 5.2 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 0.5 | 5.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.5 | 1.0 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.5 | 1.9 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 0.5 | 2.8 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.5 | 1.4 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.5 | 2.3 | GO:1902724 | mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 0.4 | 1.7 | GO:0010481 | ectoderm and mesoderm interaction(GO:0007499) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.4 | 1.3 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.4 | 8.6 | GO:2000404 | regulation of T cell migration(GO:2000404) |
| 0.4 | 15.7 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.4 | 7.8 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.4 | 0.8 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.4 | 2.3 | GO:1904925 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 0.4 | 11.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.4 | 30.3 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.4 | 17.4 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.3 | 3.0 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.3 | 6.1 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.3 | 1.0 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.3 | 1.6 | GO:0097403 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.3 | 1.9 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.3 | 1.8 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 3.0 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) |
| 0.3 | 1.4 | GO:1990418 | response to insulin-like growth factor stimulus(GO:1990418) |
| 0.3 | 9.9 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.3 | 1.7 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.3 | 10.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.3 | 0.8 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.3 | 0.3 | GO:1902958 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
| 0.3 | 3.8 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.3 | 0.8 | GO:0010160 | sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193) |
| 0.3 | 1.5 | GO:1904222 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.3 | 2.0 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.2 | 3.8 | GO:0070141 | response to UV-A(GO:0070141) |
| 0.2 | 6.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.2 | 0.5 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
| 0.2 | 0.9 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.2 | 4.6 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.2 | 3.2 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.2 | 10.7 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.2 | 0.9 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 0.2 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.2 | 2.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.2 | 0.7 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.2 | 2.4 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 19.1 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
| 0.2 | 1.6 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.2 | 2.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.2 | 2.4 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.2 | 1.0 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.2 | 0.6 | GO:0090114 | COPII-coated vesicle budding(GO:0090114) |
| 0.2 | 0.8 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 0.2 | 1.4 | GO:0045345 | positive regulation of MHC class I biosynthetic process(GO:0045345) |
| 0.2 | 3.3 | GO:0002385 | mucosal immune response(GO:0002385) |
| 0.2 | 0.7 | GO:0009972 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.2 | 1.4 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.2 | 0.7 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.2 | 1.0 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
| 0.2 | 0.8 | GO:0036343 | negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343) |
| 0.2 | 2.5 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.2 | 1.0 | GO:0072695 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.2 | 2.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 0.8 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.2 | 2.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.2 | 0.6 | GO:0042335 | cuticle development(GO:0042335) |
| 0.2 | 1.3 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 4.1 | GO:0001649 | osteoblast differentiation(GO:0001649) |
| 0.2 | 1.1 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 0.6 | GO:0036017 | response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) |
| 0.2 | 1.2 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.1 | 0.7 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.1 | 3.9 | GO:1900116 | extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.1 | 0.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.1 | 0.6 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.1 | 3.6 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
| 0.1 | 0.9 | GO:0071351 | interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351) |
| 0.1 | 0.4 | GO:0033037 | polysaccharide localization(GO:0033037) |
| 0.1 | 3.0 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.1 | 2.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.9 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.1 | 4.1 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.1 | 1.2 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.1 | 10.2 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.1 | 0.8 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.1 | 1.8 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 3.2 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.1 | 0.4 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.1 | 0.8 | GO:0007060 | male meiosis chromosome segregation(GO:0007060) |
| 0.1 | 1.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 1.0 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.6 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 0.1 | 0.8 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 0.9 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.1 | 2.8 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.1 | 0.3 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 2.4 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 1.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 0.3 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 0.8 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 0.3 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.1 | 3.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.1 | 2.7 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.6 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.1 | 4.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.3 | GO:0034130 | toll-like receptor 1 signaling pathway(GO:0034130) |
| 0.1 | 0.7 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 6.0 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 38.9 | GO:0009615 | response to virus(GO:0009615) |
| 0.1 | 0.9 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 1.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 2.2 | GO:0060065 | uterus development(GO:0060065) |
| 0.1 | 2.7 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.1 | 6.5 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.1 | 0.6 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.1 | 0.6 | GO:0070163 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.3 | GO:0002439 | chronic inflammatory response to antigenic stimulus(GO:0002439) |
| 0.1 | 0.2 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.1 | 1.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.4 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.1 | 0.3 | GO:0006429 | leucyl-tRNA aminoacylation(GO:0006429) |
| 0.1 | 0.1 | GO:0046666 | retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668) |
| 0.1 | 0.3 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.1 | 0.2 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.1 | 1.1 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
| 0.1 | 11.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.1 | 1.6 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.1 | 1.5 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 0.2 | GO:0033685 | negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106) |
| 0.1 | 1.2 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.1 | 0.3 | GO:0018197 | peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.5 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.1 | 0.5 | GO:0021778 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.1 | 0.6 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.1 | 0.6 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 4.5 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 2.9 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.1 | 0.5 | GO:0032445 | fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 0.3 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.1 | 0.6 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.1 | 1.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910) |
| 0.1 | 1.8 | GO:0030220 | platelet formation(GO:0030220) |
| 0.1 | 0.4 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 0.1 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.1 | 0.6 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.1 | 0.8 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.7 | GO:0060022 | hard palate development(GO:0060022) |
| 0.1 | 1.7 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 0.1 | GO:0042222 | interleukin-1 biosynthetic process(GO:0042222) interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 0.1 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.1 | 1.0 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.1 | 0.3 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 3.6 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.1 | 0.1 | GO:0035566 | regulation of metanephros size(GO:0035566) negative regulation of cytolysis(GO:0045918) |
| 0.1 | 2.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.5 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.1 | 1.2 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.1 | 0.2 | GO:0072223 | cell migration involved in coronary angiogenesis(GO:0060981) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.1 | 0.9 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.1 | 1.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 1.2 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.3 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.1 | 0.2 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
| 0.1 | 1.0 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.1 | 1.0 | GO:0043536 | positive regulation of blood vessel endothelial cell migration(GO:0043536) |
| 0.1 | 0.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.1 | 0.4 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 0.6 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 1.9 | GO:0045124 | regulation of bone resorption(GO:0045124) |
| 0.1 | 0.2 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.1 | 0.5 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.1 | 1.9 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 1.6 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.2 | GO:0009253 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.0 | 2.1 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.0 | 0.7 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.0 | 0.7 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.2 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) |
| 0.0 | 2.1 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.7 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.3 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.0 | 0.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.1 | GO:0050822 | peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823) |
| 0.0 | 0.3 | GO:0002370 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.0 | 1.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.7 | GO:0046520 | sphingoid biosynthetic process(GO:0046520) |
| 0.0 | 0.3 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) anterior/posterior axon guidance(GO:0033564) |
| 0.0 | 0.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.9 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.0 | 0.7 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.0 | 0.5 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.0 | 0.2 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 0.3 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.3 | GO:0048839 | inner ear development(GO:0048839) |
| 0.0 | 10.1 | GO:0042157 | lipoprotein metabolic process(GO:0042157) |
| 0.0 | 0.2 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.0 | 1.4 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.2 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 4.5 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 5.7 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.3 | GO:0010529 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 0.0 | 0.2 | GO:0032960 | regulation of inositol trisphosphate biosynthetic process(GO:0032960) |
| 0.0 | 0.6 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 0.2 | GO:0032439 | endosome localization(GO:0032439) |
| 0.0 | 3.8 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.2 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.5 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.2 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.0 | 1.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.4 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.6 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.1 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.0 | 0.7 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.4 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.3 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.5 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.0 | 0.1 | GO:0048840 | otolith morphogenesis(GO:0032474) otolith development(GO:0048840) |
| 0.0 | 0.6 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 0.1 | GO:0007162 | negative regulation of cell adhesion(GO:0007162) |
| 0.0 | 0.1 | GO:0032736 | positive regulation of interleukin-13 production(GO:0032736) |
| 0.0 | 0.4 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 1.1 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 1.2 | GO:0009247 | glycolipid biosynthetic process(GO:0009247) |
| 0.0 | 0.2 | GO:0090266 | regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.7 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.0 | 0.3 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 2.9 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 0.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 1.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.1 | GO:1900019 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.0 | 0.2 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.5 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.2 | GO:0003360 | brainstem development(GO:0003360) |
| 0.0 | 0.2 | GO:0090259 | regulation of retinal ganglion cell axon guidance(GO:0090259) dorsal root ganglion development(GO:1990791) |
| 0.0 | 0.8 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.2 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.3 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.0 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.0 | 0.2 | GO:0009409 | response to cold(GO:0009409) |
| 0.0 | 3.1 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
| 0.0 | 0.2 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.0 | 0.7 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.0 | 0.1 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.9 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.0 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.0 | 0.5 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 0.0 | 0.6 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 0.2 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.1 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.0 | 0.3 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.3 | GO:0030336 | negative regulation of cell migration(GO:0030336) |
| 0.0 | 0.4 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.5 | GO:0001958 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.0 | 0.3 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.5 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.2 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.0 | 0.3 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.0 | 0.1 | GO:0090154 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.0 | 0.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.0 | 0.1 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 0.1 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.0 | 0.2 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.0 | 0.5 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.2 | GO:0060315 | negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.0 | 0.6 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.2 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.1 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.2 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.0 | 1.4 | GO:0007286 | spermatid development(GO:0007286) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 30.5 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 2.2 | 15.5 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 1.7 | 5.1 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 1.3 | 3.8 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 1.2 | 8.2 | GO:0042825 | TAP complex(GO:0042825) |
| 1.0 | 6.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.9 | 4.7 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.8 | 26.3 | GO:0034385 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.7 | 10.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.6 | 7.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.6 | 2.3 | GO:0031213 | RSF complex(GO:0031213) |
| 0.6 | 4.0 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.6 | 1.7 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.5 | 4.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 38.3 | GO:0015030 | Cajal body(GO:0015030) |
| 0.4 | 3.4 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.4 | 1.6 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.4 | 0.8 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.3 | 4.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.3 | 7.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.3 | 0.8 | GO:0042022 | interleukin-12 receptor complex(GO:0042022) |
| 0.3 | 9.3 | GO:0098553 | integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.3 | 29.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 0.7 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.2 | 0.5 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.2 | 1.8 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.2 | 9.3 | GO:0071437 | invadopodium(GO:0071437) |
| 0.2 | 2.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 9.6 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.2 | 0.8 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.2 | 2.6 | GO:0030478 | actin cap(GO:0030478) |
| 0.2 | 1.5 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.2 | 8.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 0.7 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 0.2 | 2.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.2 | 5.0 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.2 | 0.9 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.2 | 1.4 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.2 | 19.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 19.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 1.7 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 11.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 2.5 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 4.1 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.3 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 0.4 | GO:0001534 | radial spoke(GO:0001534) |
| 0.1 | 1.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 0.4 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.1 | 1.0 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 2.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 3.0 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 13.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.7 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 1.1 | GO:0032059 | bleb(GO:0032059) |
| 0.1 | 0.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 16.8 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 15.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 2.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.6 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.1 | 5.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 22.6 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 53.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 11.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 8.2 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 1.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 11.0 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 0.3 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.1 | 0.8 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 14.5 | GO:0005769 | early endosome(GO:0005769) |
| 0.1 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 1.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 1.0 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 1.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 1.0 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 11.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 25.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 0.5 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.1 | 0.4 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 0.2 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.1 | 0.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 0.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 0.3 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.1 | 1.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.3 | GO:0071547 | piP-body(GO:0071547) |
| 0.1 | 0.2 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.0 | 1.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 20.4 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.5 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 0.6 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 3.7 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.6 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 4.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 13.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.6 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 3.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 3.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.5 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 2.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 95.1 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 2.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.2 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 12.6 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.3 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 3.4 | GO:0071944 | cell periphery(GO:0071944) |
| 0.0 | 5.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.7 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.5 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 8.1 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.0 | 0.6 | GO:0031301 | integral component of organelle membrane(GO:0031301) |
| 0.0 | 1.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 2.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 1.2 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 1.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 15.7 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.9 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.7 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.8 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.5 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.2 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 0.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.0 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.0 | 2.2 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.3 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.1 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 0.1 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 9.8 | GO:0042175 | nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175) |
| 0.0 | 0.3 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 0.1 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.4 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.0 | GO:0070703 | inner mucus layer(GO:0070702) outer mucus layer(GO:0070703) |
| 0.0 | 8.0 | GO:0005794 | Golgi apparatus(GO:0005794) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.4 | 52.5 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 3.3 | 9.9 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 2.8 | 22.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 2.7 | 10.8 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 2.5 | 12.6 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 1.7 | 7.0 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 1.6 | 12.9 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 1.4 | 5.8 | GO:0048030 | disaccharide binding(GO:0048030) |
| 1.4 | 19.3 | GO:0089720 | caspase binding(GO:0089720) |
| 1.3 | 11.8 | GO:0046977 | TAP binding(GO:0046977) TAP1 binding(GO:0046978) |
| 1.3 | 12.9 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 1.2 | 15.4 | GO:0031386 | protein tag(GO:0031386) |
| 1.1 | 3.3 | GO:0042007 | interleukin-18 binding(GO:0042007) |
| 1.1 | 10.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.9 | 3.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.9 | 21.4 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
| 0.9 | 6.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.8 | 31.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.7 | 4.5 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.7 | 38.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.7 | 5.5 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.6 | 1.9 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.6 | 4.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.6 | 1.8 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
| 0.6 | 11.8 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.5 | 15.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.5 | 1.0 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
| 0.4 | 3.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.4 | 12.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.4 | 9.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.4 | 53.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.4 | 1.5 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.4 | 1.5 | GO:0005115 | receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.4 | 1.4 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.4 | 0.7 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.3 | 1.4 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.3 | 3.1 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.3 | 11.5 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.3 | 3.0 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.3 | 20.1 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.3 | 13.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 2.8 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.3 | 0.9 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.3 | 4.0 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.3 | 6.6 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.3 | 10.7 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.3 | 1.7 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.3 | 1.4 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.3 | 0.8 | GO:0016517 | interleukin-12 receptor activity(GO:0016517) |
| 0.3 | 2.3 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.2 | 0.7 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
| 0.2 | 9.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 7.7 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.2 | 0.7 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.2 | 54.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 1.5 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.2 | 9.2 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 0.6 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.2 | 11.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 1.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.2 | 0.6 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.2 | 0.8 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.2 | 3.7 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.2 | 2.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.2 | 2.7 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.2 | 2.3 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 11.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 1.1 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.2 | 1.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 0.9 | GO:0102008 | cytosolic dipeptidase activity(GO:0102008) |
| 0.2 | 1.0 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.2 | 2.8 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.2 | 1.0 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.2 | 20.4 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.2 | 0.8 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.2 | 1.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.7 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.1 | 0.4 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.1 | 0.7 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 2.9 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 19.6 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.1 | 1.0 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 1.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 2.7 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 2.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 6.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.7 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.7 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 2.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 1.6 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.1 | 0.8 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 6.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 7.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 3.0 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.1 | 0.2 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 3.9 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 0.8 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.1 | 0.7 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 13.8 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.1 | 3.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 2.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 1.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 59.4 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 4.4 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 0.4 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 0.3 | GO:0004823 | leucine-tRNA ligase activity(GO:0004823) |
| 0.1 | 0.9 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 0.7 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 1.5 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.1 | 27.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 0.3 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.1 | 2.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.4 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.1 | 1.2 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 0.5 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 1.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.9 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 7.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 2.1 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.5 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.1 | 1.8 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 0.6 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 0.5 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.1 | 0.4 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 4.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 8.1 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 3.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.1 | 2.9 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.2 | GO:0008441 | 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441) |
| 0.1 | 0.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 1.0 | GO:0098505 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) |
| 0.1 | 1.4 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 0.2 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.1 | 0.8 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.2 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 0.7 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 1.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 0.5 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.4 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 0.1 | 0.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 1.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 0.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.5 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.1 | 0.3 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.0 | 0.6 | GO:0036122 | BMP binding(GO:0036122) |
| 0.0 | 7.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.1 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.0 | 0.7 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 0.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 6.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.1 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 0.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 1.0 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 0.5 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 18.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 1.3 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 0.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 1.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.5 | GO:0015288 | protein channel activity(GO:0015266) porin activity(GO:0015288) |
| 0.0 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 1.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.2 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.0 | 0.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 1.8 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 2.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.3 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.2 | GO:0001595 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.0 | 0.1 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.0 | 5.2 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.2 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.0 | 0.2 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.0 | 30.6 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.0 | 0.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.3 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 1.5 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.2 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.1 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884) |
| 0.0 | 0.2 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 8.0 | GO:0016746 | transferase activity, transferring acyl groups(GO:0016746) |
| 0.0 | 0.4 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 0.2 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.0 | 1.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.6 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.5 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.3 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.0 | 0.1 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.0 | 0.6 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.5 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.0 | 0.2 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 2.2 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 1.3 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.8 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 4.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.2 | GO:0051213 | dioxygenase activity(GO:0051213) |
| 0.0 | 0.0 | GO:0038187 | lipopolysaccharide receptor activity(GO:0001875) signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.0 | 0.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.6 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.8 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.1 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) |
| 0.0 | 12.1 | GO:0003700 | transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.2 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 12.6 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.5 | 19.6 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.5 | 7.3 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.5 | 27.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.4 | 7.3 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.3 | 2.3 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.3 | 7.8 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.2 | 7.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 8.1 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 4.2 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.2 | 17.3 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 7.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 2.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 12.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 16.0 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 2.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 5.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 3.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 7.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 11.4 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 1.0 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 5.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 2.9 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 2.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 1.7 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.1 | 10.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 2.9 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 3.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 3.6 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 5.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 17.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 0.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 0.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.1 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.2 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 11.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.9 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 2.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.6 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.1 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.9 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 6.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 1.2 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.9 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.4 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.4 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.2 | PID S1P S1P1 PATHWAY | S1P1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 322.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 1.3 | 21.5 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 1.1 | 4.4 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 1.0 | 21.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.7 | 13.6 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 0.6 | 5.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.6 | 28.9 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.5 | 5.4 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.5 | 34.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.4 | 8.9 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 17.0 | REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
| 0.4 | 3.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.3 | 11.9 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.2 | 5.9 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 6.8 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.2 | 15.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 14.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 12.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 4.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.6 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 2.1 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.1 | 7.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 1.4 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 3.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 1.0 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.1 | 2.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 2.2 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 0.8 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 2.6 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 2.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.6 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.1 | 3.9 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 2.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 1.0 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 1.0 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.2 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.7 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 2.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.2 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 2.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.9 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.8 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.0 | 0.6 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 1.1 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 1.1 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.4 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 3.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 1.1 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 1.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.7 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.3 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 1.4 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.4 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 1.4 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.2 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.0 | 0.4 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 0.2 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.4 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 1.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.2 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.8 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.3 | REACTOME INTERFERON SIGNALING | Genes involved in Interferon Signaling |