ISMARA results: IRX5

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for IRX5

Z-value: 0.64

Motif logo

Transcription factors associated with IRX5

Gene Symbol	Gene ID	Gene Info
IRX5 Ensembl NCBI GeneCards UniProt	ENSG00000176842.10	iroquois homeobox 5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRX5	hg19_v2_chr16_+_54964740_54964789	0.35	1.3e-01	Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

No targets for IRX5

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	2.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.2	1.1	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	1.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.8	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.7	GO:0034421	post-translational protein acetylation(GO:0034421)
0.2	0.6	GO:0071264	regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0	0.6	GO:1903874	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.2	0.5	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.5	GO:0032053	ciliary basal body organization(GO:0032053)

Showing 1 to 10 of 51 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	1.1	GO:0005844	polysome(GO:0005844)
0.0	0.8	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.6	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.5	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.4	GO:0034684	integrin alphav-beta5 complex(GO:0034684)
0.1	0.4	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.0	0.4	GO:0000801	central element(GO:0000801)

Showing 1 to 10 of 28 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	GO:0043515	kinetochore binding(GO:0043515)
0.0	1.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	0.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.6	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	0.5	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.5	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.4	GO:0001054	RNA polymerase I activity(GO:0001054)

Showing 1 to 10 of 35 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
1.5	PID PLK1 PATHWAY	PLK1 signaling events
0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Total log-likelihood	Term	Description
0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Showing 1 to 9 of 9 entries

Results for IRX5

Z-value: 0.64

Motif logo

Transcription factors associated with IRX5

Activity-expression correlation:

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

No targets for IRX5

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: