avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
IRX6 Links Ensembl NCBI GeneCards UniProt	ENSG00000159387.7	iroquois homeobox 6
IRX4 Links Ensembl NCBI GeneCards UniProt	ENSG00000113430.5	iroquois homeobox 4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRX4	hg19_v2_chr5_-_1882858_1883003	-0.72	3.3e-04	Click!
IRX6	hg19_v2_chr16_+_55357672_55357672	0.01	9.6e-01	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:1990926	short-term synaptic potentiation(GO:1990926)
0.2	1.6	GO:1903899	lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1	0.8	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1	0.4	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	0.5	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.3	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.5	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	1.2	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	1.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.2	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1	1.3	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	1.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.3	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.2	GO:0016062	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0	0.3	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	1.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.2	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.6	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.6	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.8	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.8	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0034684	integrin alphav-beta5 complex(GO:0034684)
0.2	1.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	0.6	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	1.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.8	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0044305	calyx of Held(GO:0044305)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	1.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0098843	postsynaptic endocytic zone(GO:0098843)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.4	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1	0.5	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.3	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	0.8	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.2	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.1	1.6	GO:0002162	dystroglycan binding(GO:0002162)
0.0	1.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.8	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.4	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	1.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	1.3	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation