ISMARA results: JUND

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for JUND

Z-value: 1.77

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Transcription factors associated with JUND

Gene Symbol	Gene ID	Gene Info
JUND Ensembl NCBI GeneCards UniProt	ENSG00000130522.4	JunD proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
JUND	hg19_v2_chr19_-_18391708_18391739	0.92	1.2e-08	Click!

Activity profile of JUND motif

Sorted Z-values of JUND motif

No targets for JUND

Network of associatons between targets according to the STRING database.

First level regulatory network of JUND

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.6	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.2	5.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.8	5.6	GO:0071725	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	5.2	GO:0007098	centrosome cycle(GO:0007098)
0.9	5.1	GO:0061143	alveolar primary septum development(GO:0061143)
0.3	5.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	4.8	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.2	4.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.3	3.8	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.4	3.4	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)

Showing 1 to 10 of 91 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.6	5.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.4	5.3	GO:0005577	fibrinogen complex(GO:0005577)
0.4	5.2	GO:0070652	HAUS complex(GO:0070652)
0.1	4.9	GO:0045095	keratin filament(GO:0045095)
0.0	4.6	GO:0005882	intermediate filament(GO:0005882)
0.0	4.4	GO:0032587	ruffle membrane(GO:0032587)
0.3	4.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	4.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	4.2	GO:0015030	Cajal body(GO:0015030)

Showing 1 to 10 of 33 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.0	GO:0097110	scaffold protein binding(GO:0097110)
0.8	5.6	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	5.1	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	4.9	GO:0031072	heat shock protein binding(GO:0031072)
0.3	4.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	4.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	4.2	GO:0008083	growth factor activity(GO:0008083)
0.0	3.6	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	3.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	3.3	GO:0051787	misfolded protein binding(GO:0051787)

Showing 1 to 10 of 61 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	6.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	6.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	4.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	3.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	3.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	3.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	2.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.5	PID RHOA PATHWAY	RhoA signaling pathway

Showing 1 to 10 of 15 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	3.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	3.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	3.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	3.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	2.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	2.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis

Showing 1 to 10 of 29 entries

Results for JUND

Z-value: 1.77

Motif logo

Transcription factors associated with JUND

Activity-expression correlation:

Activity profile of JUND motif

Sorted Z-values of JUND motif

No targets for JUND

Network of associatons between targets according to the STRING database.

First level regulatory network of JUND

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: