ISMARA results: KLF13

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF13

Z-value: 1.41

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Transcription factors associated with KLF13

Gene Symbol	Gene ID	Gene Info
KLF13 Ensembl NCBI GeneCards UniProt	ENSG00000169926.5	Kruppel like factor 13

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
KLF13	hg19_v2_chr15_+_31619013_31619095	-0.48	3.2e-02	Click!

Activity profile of KLF13 motif

Sorted Z-values of KLF13 motif

No targets for KLF13

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.3	GO:1904784	NLRP1 inflammasome complex assembly(GO:1904784)
0.3	5.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	4.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.1	3.3	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.0	2.8	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2	2.7	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.2	2.7	GO:0015074	DNA integration(GO:0015074)
0.0	2.4	GO:0008088	axo-dendritic transport(GO:0008088)
0.8	2.3	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	2.3	GO:0035988	chondrocyte proliferation(GO:0035988)

Showing 1 to 10 of 81 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	6.3	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.3	5.2	GO:0061700	GATOR2 complex(GO:0061700)
0.1	4.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	3.0	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	2.7	GO:0072686	mitotic spindle(GO:0072686)
0.1	2.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	2.5	GO:0035579	specific granule membrane(GO:0035579)
0.1	2.4	GO:0035253	ciliary rootlet(GO:0035253)
0.0	1.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	1.2	GO:0030893	meiotic cohesin complex(GO:0030893)

Showing 1 to 10 of 39 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.7	3.3	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	3.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.4	GO:0019894	kinesin binding(GO:0019894)
0.8	2.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.2	2.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	2.3	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	2.0	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.4	1.6	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.4	1.5	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)

Showing 1 to 10 of 55 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	5.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	4.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.4	PID FGF PATHWAY	FGF signaling pathway
0.0	1.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.0	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	4.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.2	3.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	2.4	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	2.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	2.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.9	REACTOME MEIOSIS	Genes involved in Meiosis
0.1	1.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism

Showing 1 to 10 of 25 entries

Results for KLF13

Z-value: 1.41

Motif logo

Transcription factors associated with KLF13

Activity-expression correlation:

Activity profile of KLF13 motif

Sorted Z-values of KLF13 motif

No targets for KLF13

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: