ISMARA results: KLF15

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for KLF15

Z-value: 1.11

Motif logo

Transcription factors associated with KLF15

Gene Symbol	Gene ID	Gene Info
KLF15 Ensembl NCBI GeneCards UniProt	ENSG00000163884.3	Kruppel like factor 15

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
KLF15	hg19_v2_chr3_-_126076264_126076305	-0.75	1.4e-04	Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

No targets for KLF15

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	5.9	GO:1904761	negative regulation of myofibroblast differentiation(GO:1904761)
0.8	4.5	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	2.9	GO:0090307	mitotic spindle assembly(GO:0090307)
0.0	2.8	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.1	2.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3	2.3	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	2.3	GO:0071494	cellular response to UV-C(GO:0071494)
0.2	2.3	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0	2.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	2.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)

Showing 1 to 10 of 174 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.7	GO:0016607	nuclear speck(GO:0016607)
0.6	4.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.2	3.4	GO:0097227	sperm annulus(GO:0097227)
0.0	3.2	GO:0002102	podosome(GO:0002102)
0.1	2.9	GO:0097228	sperm principal piece(GO:0097228)
0.0	2.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.9	GO:0001940	male pronucleus(GO:0001940)
0.0	1.9	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	1.7	GO:0034364	high-density lipoprotein particle(GO:0034364)

Showing 1 to 10 of 78 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.7	GO:0042393	histone binding(GO:0042393)
0.1	3.6	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	3.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	2.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	2.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	2.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	2.2	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.1	2.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	2.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	1.9	GO:1990226	histone methyltransferase binding(GO:1990226)

Showing 1 to 10 of 107 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	4.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	2.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.5	PID CDC42 PATHWAY	CDC42 signaling events
0.1	2.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	2.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.8	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	1.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events

Showing 1 to 10 of 34 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	2.6	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	2.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	2.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	2.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	2.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	1.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling

Showing 1 to 10 of 41 entries

Results for KLF15

Z-value: 1.11

Motif logo

Transcription factors associated with KLF15

Activity-expression correlation:

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

No targets for KLF15

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: