ISMARA results: KLF16

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for KLF16_SP2

Z-value: 7.55

Motif logo

Transcription factors associated with KLF16_SP2

Gene Symbol	Gene ID	Gene Info
KLF16 Ensembl NCBI GeneCards UniProt	ENSG00000129911.4	Kruppel like factor 16
SP2 Ensembl NCBI GeneCards UniProt	ENSG00000167182.11	Sp2 transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SP2	hg19_v2_chr17_+_45973516_45973618	-0.91	2.5e-08	Click!
KLF16	hg19_v2_chr19_-_1863567_1863586	0.08	7.5e-01	Click!

Activity profile of KLF16_SP2 motif

Sorted Z-values of KLF16_SP2 motif

No targets for KLF16_SP2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF16_SP2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	157.6	GO:0006414	translational elongation(GO:0006414)
7.1	64.0	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
10.3	62.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.5	54.5	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.4	51.4	GO:0006805	xenobiotic metabolic process(GO:0006805)
1.9	50.0	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
8.3	49.5	GO:1903412	response to bile acid(GO:1903412)
0.3	43.9	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
3.0	42.4	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
3.0	42.2	GO:0007144	female meiosis I(GO:0007144)

Showing 1 to 10 of 1,373 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	894.0	GO:0016021	integral component of membrane(GO:0016021)
0.7	96.4	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
3.1	74.9	GO:0005861	troponin complex(GO:0005861)
1.6	74.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.5	62.8	GO:0005581	collagen trimer(GO:0005581)
0.8	61.0	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
1.0	54.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.4	52.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.6	49.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	47.0	GO:0005759	mitochondrial matrix(GO:0005759)

Showing 1 to 10 of 403 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	159.2	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6	154.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.5	77.3	GO:0000149	SNARE binding(GO:0000149)
5.4	75.5	GO:0031014	troponin T binding(GO:0031014)
1.2	59.0	GO:0017075	syntaxin-1 binding(GO:0017075)
11.0	55.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
4.0	47.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
7.3	43.9	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
2.7	40.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
2.0	39.8	GO:0039706	co-receptor binding(GO:0039706)

Showing 1 to 10 of 826 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	44.3	ST GAQ PATHWAY	G alpha q Pathway
0.6	38.8	NABA COLLAGENS	Genes encoding collagen proteins
0.4	37.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.3	32.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.4	29.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.2	25.5	PID E2F PATHWAY	E2F transcription factor network
0.3	24.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.3	24.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.9	23.6	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	23.0	PID AURORA B PATHWAY	Aurora B signaling

Showing 1 to 10 of 105 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	110.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.6	96.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
1.0	73.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.9	70.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.1	68.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.8	58.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
3.3	56.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.7	54.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
1.7	50.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.8	44.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand

Showing 1 to 10 of 195 entries

Results for KLF16_SP2

Z-value: 7.55

Motif logo

Transcription factors associated with KLF16_SP2

Activity-expression correlation:

Activity profile of KLF16_SP2 motif

Sorted Z-values of KLF16_SP2 motif

No targets for KLF16_SP2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF16_SP2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: