Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for KLF3

Z-value: 1.04

Motif logo

Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_38665827-0.331.5e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.2 1.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.6 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 0.8 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 0.8 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.8 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.7 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.3 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.1 0.7 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.5 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.4 GO:0060051 negative regulation of protein ADP-ribosylation(GO:0010836) negative regulation of protein glycosylation(GO:0060051)
0.0 0.2 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 1.0 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.4 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:1904300 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.7 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 1.0 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 1.0 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.9 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.2 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.8 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.4 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.8 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.3 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.6 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 1.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875) platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression