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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for KLF6
Z-value: 2.77
Motif logo
Transcription factors associated with KLF6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
KLF6
|
ENSG00000067082.10 | Kruppel like factor 6 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF6 | hg19_v2_chr10_-_3827417_3827473 | 0.76 | 9.7e-05 | Click! |
Activity profile of KLF6 motif
Sorted Z-values of KLF6 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 20.2 | GO:1902910 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 5.0 | 20.0 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 1.5 | 21.1 | GO:1901166 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 1.4 | 4.2 | GO:0050720 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) |
| 1.0 | 3.1 | GO:0015728 | mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780) |
| 1.0 | 3.0 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 1.0 | 1.0 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.8 | 2.3 | GO:1904761 | negative regulation of myofibroblast differentiation(GO:1904761) |
| 0.7 | 7.9 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.7 | 2.0 | GO:0061193 | sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193) |
| 0.6 | 1.8 | GO:0038190 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.6 | 1.8 | GO:2000657 | regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657) |
| 0.6 | 2.4 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.6 | 3.9 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.6 | 1.7 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) |
| 0.6 | 6.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.6 | 1.7 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.5 | 2.0 | GO:0072086 | specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268) |
| 0.5 | 1.4 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.5 | 2.3 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.4 | 1.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.4 | 1.9 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.4 | 1.9 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 0.4 | 1.9 | GO:0030862 | positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 0.4 | 1.1 | GO:0035508 | positive regulation of myosin-light-chain-phosphatase activity(GO:0035508) |
| 0.4 | 1.5 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.4 | 1.1 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.3 | 1.0 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.3 | 5.2 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.3 | 1.4 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.3 | 2.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.3 | 2.7 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 2.0 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.3 | 1.7 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
| 0.3 | 0.9 | GO:0097198 | histone H3-K36 trimethylation(GO:0097198) |
| 0.3 | 1.5 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.3 | 5.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.3 | 1.8 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.3 | 1.1 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.3 | 0.9 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.3 | 0.8 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 0.3 | 1.0 | GO:0035905 | N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.3 | 0.8 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.3 | 1.5 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) |
| 0.2 | 0.7 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.2 | 2.7 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.2 | 0.9 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.2 | 2.1 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
| 0.2 | 0.7 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 0.2 | 1.9 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.2 | 3.9 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.2 | 1.1 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.2 | 6.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.2 | 10.3 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.2 | 1.1 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.2 | 3.9 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 0.8 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.2 | 0.8 | GO:1904499 | glial cell fate determination(GO:0007403) negative regulation of mitotic cell cycle, embryonic(GO:0045976) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.2 | 1.1 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.2 | 1.3 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.2 | 1.4 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.2 | 0.5 | GO:0072034 | primary prostatic bud elongation(GO:0060516) bronchus cartilage development(GO:0060532) common bile duct development(GO:0061009) lung smooth muscle development(GO:0061145) renal vesicle induction(GO:0072034) |
| 0.2 | 1.8 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.2 | 1.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.2 | 1.9 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.2 | 1.0 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.2 | 0.5 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.2 | 0.5 | GO:0086098 | angiotensin-activated signaling pathway involved in heart process(GO:0086098) negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.2 | 1.7 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.2 | 1.3 | GO:0090166 | Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306) |
| 0.2 | 1.0 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.2 | 5.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 1.3 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.2 | 4.6 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.2 | 2.0 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.2 | 0.5 | GO:0035625 | epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.1 | 5.9 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.6 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.1 | 1.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.4 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 0.9 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 7.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 0.5 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 0.1 | 0.4 | GO:0045799 | negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.1 | 0.7 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.1 | 1.2 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.1 | 1.6 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.1 | 0.1 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.1 | 0.3 | GO:0040040 | thermosensory behavior(GO:0040040) |
| 0.1 | 1.2 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.1 | 0.6 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.1 | 0.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.1 | 1.3 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.1 | 1.4 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 2.4 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.1 | 0.5 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.1 | 1.0 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 1.4 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.1 | 0.9 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 1.4 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 0.1 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
| 0.1 | 0.8 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 0.5 | GO:0051944 | glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) negative regulation of dopamine receptor signaling pathway(GO:0060160) regulation of locomotion involved in locomotory behavior(GO:0090325) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168) |
| 0.1 | 0.5 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.1 | 0.5 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 1.4 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.1 | 1.9 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.3 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 1.0 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.8 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 0.8 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 2.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 1.6 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.1 | 0.3 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 0.1 | 0.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 0.8 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 0.5 | GO:0098728 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 0.5 | GO:0034165 | positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) |
| 0.1 | 1.3 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 1.6 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 0.9 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.1 | 1.0 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 6.9 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.1 | 0.5 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.1 | 1.4 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 0.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.1 | 1.6 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 1.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 0.4 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.1 | 0.2 | GO:0090222 | centrosome-templated microtubule nucleation(GO:0090222) |
| 0.1 | 1.0 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261) |
| 0.1 | 0.3 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 0.1 | 1.0 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.1 | 0.5 | GO:0042476 | odontogenesis(GO:0042476) |
| 0.1 | 0.3 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.1 | 4.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 1.1 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.1 | 1.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.1 | 3.1 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 1.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 0.5 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.1 | 1.2 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 0.6 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.1 | 0.6 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.1 | 0.9 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.1 | 1.5 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 0.3 | GO:0060028 | somatic muscle development(GO:0007525) non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) convergent extension involved in axis elongation(GO:0060028) axis elongation involved in somitogenesis(GO:0090245) |
| 0.1 | 0.3 | GO:0002019 | regulation of renal output by angiotensin(GO:0002019) negative regulation of gap junction assembly(GO:1903597) |
| 0.1 | 3.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.4 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.1 | 2.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 0.7 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 1.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.3 | GO:1903299 | regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299) |
| 0.0 | 0.7 | GO:0072104 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 0.0 | 0.2 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 0.0 | 0.2 | GO:0033629 | negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.0 | 0.5 | GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.0 | 1.7 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.8 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.2 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
| 0.0 | 1.0 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.0 | 0.5 | GO:0036089 | cleavage furrow formation(GO:0036089) |
| 0.0 | 1.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.4 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.0 | 1.2 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 2.1 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 1.8 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.9 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.5 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.0 | 0.2 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.0 | 0.6 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.8 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.0 | 1.0 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.3 | GO:0015870 | acetylcholine transport(GO:0015870) |
| 0.0 | 1.6 | GO:0006882 | cellular zinc ion homeostasis(GO:0006882) |
| 0.0 | 0.1 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.0 | 0.2 | GO:0046108 | uridine metabolic process(GO:0046108) |
| 0.0 | 1.2 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.7 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 0.3 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.0 | 0.8 | GO:2000146 | negative regulation of locomotion(GO:0040013) negative regulation of cell motility(GO:2000146) |
| 0.0 | 1.5 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.0 | 0.4 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.2 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.0 | 1.6 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.2 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.0 | 0.5 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.9 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 0.7 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
| 0.0 | 0.4 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.0 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.3 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.0 | 0.9 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.5 | GO:0046887 | positive regulation of hormone secretion(GO:0046887) |
| 0.0 | 1.9 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 1.2 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.0 | 2.6 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 0.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 2.5 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 0.4 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.3 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.0 | 5.4 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 3.4 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.2 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.0 | 0.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.1 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.8 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 1.0 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 1.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.4 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.2 | GO:0051968 | positive regulation of synaptic transmission, glutamatergic(GO:0051968) |
| 0.0 | 0.2 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.0 | 0.5 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.0 | 0.2 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.4 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.2 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.0 | 1.2 | GO:0051057 | positive regulation of small GTPase mediated signal transduction(GO:0051057) |
| 0.0 | 0.6 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.0 | 0.1 | GO:0030167 | proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.0 | 0.8 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.0 | 0.6 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) establishment of integrated proviral latency(GO:0075713) |
| 0.0 | 0.2 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
| 0.0 | 0.4 | GO:0010827 | regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324) |
| 0.0 | 0.1 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
| 0.0 | 0.9 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.3 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.0 | 0.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.4 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.0 | 2.1 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 2.2 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.2 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.0 | 0.6 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.0 | 0.5 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 0.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 1.9 | GO:0001523 | retinoid metabolic process(GO:0001523) |
| 0.0 | 0.2 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.0 | 0.1 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 1.1 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 1.3 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.1 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.0 | 0.3 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.9 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.0 | 0.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 0.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.0 | 0.3 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.3 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.5 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.6 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.0 | 1.0 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.7 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.0 | 0.1 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.0 | 1.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.1 | GO:0042482 | positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172) |
| 0.0 | 0.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.1 | GO:0032098 | regulation of appetite(GO:0032098) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 20.9 | GO:0097386 | glial cell projection(GO:0097386) |
| 0.7 | 6.7 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.4 | 1.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.4 | 1.1 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.3 | 1.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.3 | 1.7 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.3 | 1.9 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.3 | 0.9 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.3 | 5.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.3 | 1.9 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.2 | 2.0 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.2 | 1.1 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.2 | 0.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.2 | 5.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 3.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 0.5 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.2 | 1.8 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 1.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 6.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.8 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.1 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.1 | 3.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.8 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.1 | 2.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.3 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.1 | 0.4 | GO:0071664 | catenin-TCF7L2 complex(GO:0071664) gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.1 | 1.4 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.8 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 1.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 1.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 1.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 15.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 1.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 10.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.4 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.4 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 0.7 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 2.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 1.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.5 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.1 | 0.7 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 4.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.0 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.2 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.1 | 3.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.8 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 2.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 3.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 1.3 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 0.8 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.0 | 0.8 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 5.7 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.2 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.0 | 0.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.6 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 1.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 1.0 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 1.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 0.2 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 1.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 1.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.8 | GO:1903293 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 0.7 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 1.1 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 2.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 2.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.6 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.2 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 9.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.2 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.0 | 1.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 0.5 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 2.1 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.4 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 2.8 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 4.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.0 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.1 | GO:0033647 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.0 | 0.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 1.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 20.0 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 1.0 | 3.1 | GO:0015130 | mevalonate transmembrane transporter activity(GO:0015130) |
| 0.8 | 20.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.8 | 4.2 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.8 | 2.3 | GO:0016768 | spermine synthase activity(GO:0016768) |
| 0.6 | 6.8 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.5 | 1.4 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.4 | 1.7 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.4 | 2.7 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.3 | 1.3 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.3 | 1.0 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.3 | 1.8 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.3 | 1.1 | GO:0008184 | purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184) |
| 0.3 | 1.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.2 | 2.4 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.2 | 1.9 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.2 | 5.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.2 | 1.9 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.2 | 1.4 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.2 | 1.2 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 0.2 | 2.0 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 0.7 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.2 | 7.4 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.2 | 1.5 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.2 | 4.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.2 | 0.6 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.2 | 0.5 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.2 | 3.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 24.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 1.5 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.2 | 0.5 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.2 | 0.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 0.6 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.2 | 0.6 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.2 | 2.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 0.5 | GO:0051380 | alpha2-adrenergic receptor activity(GO:0004938) norepinephrine binding(GO:0051380) |
| 0.1 | 1.9 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.7 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 1.9 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.1 | 1.0 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.1 | 0.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 0.9 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 1.0 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 0.9 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 0.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 0.4 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.1 | 0.7 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.1 | 1.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 0.5 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.1 | 2.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 1.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 1.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 1.0 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 0.4 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.1 | 2.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 0.5 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.1 | 0.4 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.1 | 0.5 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 5.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 0.5 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 1.6 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 0.3 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.1 | 0.9 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 1.2 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.8 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 1.1 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.1 | 0.4 | GO:0004572 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572) |
| 0.1 | 0.2 | GO:0003826 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.1 | 1.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 1.7 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.1 | 1.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 2.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 2.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 1.9 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.1 | 0.5 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.1 | 0.9 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.1 | 0.4 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 10.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 0.9 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.7 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 1.8 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 2.9 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.1 | 1.8 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 1.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.1 | 0.5 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 1.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.3 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.0 | 0.2 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.0 | 6.3 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 1.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 1.4 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 6.4 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 1.1 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 1.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 1.8 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 1.1 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 1.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.5 | GO:0003700 | transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 2.7 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.3 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.2 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.0 | 0.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 2.2 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 0.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 3.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0031711 | peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) |
| 0.0 | 0.1 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.0 | 1.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 1.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.9 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 1.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 1.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 1.2 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.6 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 2.7 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 1.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.9 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.9 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.8 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 1.5 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 2.6 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.2 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.0 | 0.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 2.6 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.1 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.0 | 1.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.1 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.0 | 1.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 1.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.8 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 1.3 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 1.0 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.8 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.9 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.1 | GO:0004104 | acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104) |
| 0.0 | 0.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 2.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.8 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.0 | 2.6 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 2.8 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.4 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 1.7 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.2 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.0 | 0.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.7 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.2 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 0.1 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.0 | 0.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.0 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.4 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 3.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.1 | 2.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 5.4 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 6.4 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 8.1 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 5.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 2.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 5.7 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 21.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 0.9 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 2.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 4.9 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 2.2 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 9.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 1.0 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 1.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 6.4 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 2.2 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.5 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 1.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 2.3 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 2.3 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.6 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 2.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 8.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.5 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 2.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.8 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 0.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.5 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.4 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.3 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.9 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.3 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.7 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 18.9 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.4 | 7.9 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.3 | 18.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 1.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 5.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 2.7 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 3.6 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.1 | 3.1 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.6 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.1 | 2.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 1.3 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.1 | 2.9 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 1.0 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 0.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 2.9 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 4.4 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 0.5 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.1 | 1.2 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.1 | 2.4 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 2.0 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 4.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 1.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.1 | 9.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.8 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 1.0 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 2.0 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 0.7 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.3 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.0 | 1.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 1.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 3.9 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.1 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.8 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.7 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 3.1 | REACTOME SIGNALING BY NOTCH1 | Genes involved in Signaling by NOTCH1 |
| 0.0 | 1.1 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.3 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 1.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.8 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 1.1 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.9 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.8 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 2.1 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.5 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 0.4 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.3 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.0 | 0.4 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.3 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.3 | REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |
| 0.0 | 0.5 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.5 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.5 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 0.7 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.2 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |