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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF7

Z-value: 0.39

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
ENSG00000118263.10 Kruppel like factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208030886_2080309170.331.6e-01Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway