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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LEF1

Z-value: 1.65

Motif logo

Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
ENSG00000138795.5 lymphoid enhancer binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LEF1hg19_v2_chr4_-_109087906_1090879530.741.7e-04Click!

Activity profile of LEF1 motif

Sorted Z-values of LEF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.4 GO:0060901 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
1.0 4.2 GO:0009956 radial pattern formation(GO:0009956)
0.7 2.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.6 1.9 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 3.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.6 1.7 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.5 2.7 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.5 2.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 5.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.5 1.8 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.5 1.8 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.4 4.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.4 2.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 1.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.1 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.0 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.3 8.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 2.4 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 5.1 GO:0015816 glycine transport(GO:0015816)
0.3 2.0 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 0.8 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.3 0.8 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.3 1.3 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 2.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.7 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.2 4.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 1.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 1.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 0.9 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.2 2.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 1.9 GO:0003383 apical constriction(GO:0003383)
0.2 3.4 GO:0006600 creatine metabolic process(GO:0006600)
0.2 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 2.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.2 1.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 0.9 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 2.6 GO:0001778 plasma membrane repair(GO:0001778)
0.2 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 1.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 2.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 1.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 5.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 1.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.8 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.4 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 1.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.7 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.8 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.8 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 2.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 1.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.6 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.5 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.5 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.3 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.6 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 3.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.7 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 4.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 1.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.0 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 3.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 2.1 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.1 0.8 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 1.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 3.8 GO:0010107 potassium ion import(GO:0010107)
0.1 2.0 GO:0015695 organic cation transport(GO:0015695)
0.1 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.8 GO:0060674 placenta blood vessel development(GO:0060674)
0.1 2.1 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.8 GO:0060074 synapse maturation(GO:0060074)
0.1 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.8 GO:0033327 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 1.9 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 2.7 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 1.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.6 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.7 GO:0030575 nuclear body organization(GO:0030575)
0.0 1.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.5 GO:0003264 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.0 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.8 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.4 GO:0090181 regulation of cholesterol biosynthetic process(GO:0045540) regulation of cholesterol metabolic process(GO:0090181)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:2000843 testosterone secretion(GO:0035936) regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 5.2 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.6 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 1.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 2.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522) histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 1.3 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 2.7 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 2.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 2.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.2 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 3.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.6 4.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.6 1.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 2.0 GO:0031905 early endosome lumen(GO:0031905)
0.4 1.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.4 1.1 GO:0075341 host cell PML body(GO:0075341)
0.3 2.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 2.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 0.8 GO:0008623 CHRAC(GO:0008623)
0.2 1.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 1.7 GO:0016013 syntrophin complex(GO:0016013)
0.2 2.9 GO:0061700 GATOR2 complex(GO:0061700)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.2 6.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 6.5 GO:0030057 desmosome(GO:0030057)
0.1 3.6 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:1903349 omegasome membrane(GO:1903349)
0.1 1.0 GO:0032437 cuticular plate(GO:0032437)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.0 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 11.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0032059 bleb(GO:0032059)
0.1 1.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 9.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)
0.0 3.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 1.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 4.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 1.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.4 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.5 GO:0000785 chromatin(GO:0000785)
0.0 3.8 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.9 3.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.9 2.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 3.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.6 1.8 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.5 1.5 GO:0019150 D-ribulokinase activity(GO:0019150)
0.5 0.5 GO:0031690 adrenergic receptor binding(GO:0031690)
0.5 2.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 1.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 1.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.3 5.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 3.4 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.8 GO:1990175 EH domain binding(GO:1990175)
0.2 2.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.4 GO:0045118 azole transporter activity(GO:0045118)
0.2 1.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 3.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 2.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.7 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.9 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 2.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.7 GO:0042835 BRE binding(GO:0042835)
0.1 1.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 4.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 2.0 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 2.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.9 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.6 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 0.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 3.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 4.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 3.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 4.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 1.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 3.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0008266 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 5.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 1.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 11.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 10.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0005119 smoothened binding(GO:0005119)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 3.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.3 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.8 PID ARF 3PATHWAY Arf1 pathway
0.1 1.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 5.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 4.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.5 PID P73PATHWAY p73 transcription factor network
0.0 3.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 12.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 4.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 6.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 7.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 2.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 3.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 5.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism