ISMARA results: LHX8

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for LHX8

Z-value: 0.51

Motif logo

Transcription factors associated with LHX8

Gene Symbol	Gene ID	Gene Info
LHX8 Ensembl NCBI GeneCards UniProt	ENSG00000162624.10	LIM homeobox 8

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LHX8	hg19_v2_chr1_+_75594119_75594119	-0.67	1.3e-03	Click!

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

No targets for LHX8

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.1	GO:0016266	O-glycan processing(GO:0016266)
0.2	1.2	GO:1903786	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0	1.2	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	1.0	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.6	GO:1904793	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0	0.6	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.0	0.6	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.6	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	0.5	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)

Showing 1 to 10 of 57 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0031673	H zone(GO:0031673)
0.0	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.6	GO:0070369	Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.6	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.5	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.5	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.4	GO:0005595	collagen type XII trimer(GO:0005595)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.4	GO:0036449	microtubule minus-end(GO:0036449)

Showing 1 to 10 of 22 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	1.2	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0	1.2	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	1.0	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.9	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.5	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)

Showing 1 to 10 of 32 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
1.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Total log-likelihood	Term	Description
2.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
1.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication

Showing 1 to 10 of 10 entries

Results for LHX8

Z-value: 0.51

Motif logo

Transcription factors associated with LHX8

Activity-expression correlation:

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

No targets for LHX8

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: