ISMARA results: MAFB

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAFB

Z-value: 2.61

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Transcription factors associated with MAFB

Gene Symbol	Gene ID	Gene Info
MAFB Ensembl NCBI GeneCards UniProt	ENSG00000204103.2	MAF bZIP transcription factor B

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MAFB	hg19_v2_chr20_-_39317868_39317884	0.53	1.7e-02	Click!

Activity profile of MAFB motif

Sorted Z-values of MAFB motif

No targets for MAFB

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	9.5	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2	8.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	8.4	GO:0061436	establishment of skin barrier(GO:0061436)
0.1	7.9	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
1.8	7.2	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.4	7.0	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	5.9	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4	5.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.4	5.5	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
1.7	5.2	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)

Showing 1 to 10 of 665 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	17.3	GO:0045095	keratin filament(GO:0045095)
0.1	8.9	GO:0042641	actomyosin(GO:0042641)
0.0	8.8	GO:0043296	apical junction complex(GO:0043296)
0.3	7.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	7.6	GO:0016605	PML body(GO:0016605)
0.7	7.4	GO:0005955	calcineurin complex(GO:0005955)
0.0	7.4	GO:0001726	ruffle(GO:0001726)
0.5	7.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	7.0	GO:0097228	sperm principal piece(GO:0097228)
0.1	6.4	GO:0008023	transcription elongation factor complex(GO:0008023)

Showing 1 to 10 of 278 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	18.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	14.6	GO:0045296	cadherin binding(GO:0045296)
0.2	12.7	GO:0042169	SH2 domain binding(GO:0042169)
0.1	9.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	9.0	GO:0005525	GTP binding(GO:0005525)
0.0	8.0	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
0.5	7.5	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	7.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	7.1	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	7.0	GO:0051015	actin filament binding(GO:0051015)

Showing 1 to 10 of 398 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	13.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	12.1	PID NOTCH PATHWAY	Notch signaling pathway
0.1	12.0	PID PLK1 PATHWAY	PLK1 signaling events
0.2	10.0	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	7.7	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	6.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	6.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	5.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	5.0	PID S1P S1P4 PATHWAY	S1P4 pathway

Showing 1 to 10 of 82 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	8.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	8.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	7.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	7.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	5.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	5.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	5.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	4.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	4.8	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1

Showing 1 to 10 of 118 entries

Results for MAFB

Z-value: 2.61

Motif logo

Transcription factors associated with MAFB

Activity-expression correlation:

Activity profile of MAFB motif

Sorted Z-values of MAFB motif

No targets for MAFB

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: