ISMARA results: MECOM

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MECOM

Z-value: 0.30

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Transcription factors associated with MECOM

Gene Symbol	Gene ID	Gene Info
MECOM Ensembl NCBI GeneCards UniProt	ENSG00000085276.13	MDS1 and EVI1 complex locus

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MECOM	hg19_v2_chr3_-_169381166_169381181	-0.35	1.3e-01	Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

No targets for MECOM

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.4	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.0	0.2	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0	0.1	GO:0045720	negative regulation of integrin biosynthetic process(GO:0045720)
0.0	0.1	GO:0051866	general adaptation syndrome(GO:0051866)
0.0	0.1	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0	0.1	GO:0033967	box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)

Showing 1 to 10 of 26 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.2	GO:0004794	L-threonine ammonia-lyase activity(GO:0004794)
0.0	0.1	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0	0.1	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.0	0.1	GO:0036009	protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0	0.1	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)

Showing 1 to 10 of 12 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions

Showing 1 to 1 of 1 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators

Showing 1 to 2 of 2 entries

Results for MECOM

Z-value: 0.30

Motif logo

Transcription factors associated with MECOM

Activity-expression correlation:

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

No targets for MECOM

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: