ISMARA results: MSX2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MSX2

Z-value: 0.64

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Transcription factors associated with MSX2

Gene Symbol	Gene ID	Gene Info
MSX2 Ensembl NCBI GeneCards UniProt	ENSG00000120149.7	msh homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MSX2	hg19_v2_chr5_+_174151536_174151610	0.87	4.9e-07	Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

No targets for MSX2

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.6	1.8	GO:0099558	maintenance of synapse structure(GO:0099558)
0.4	1.7	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	1.7	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	1.3	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.1	1.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	1.1	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.9	GO:0019236	response to pheromone(GO:0019236)
0.0	0.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2	0.7	GO:0009786	regulation of asymmetric cell division(GO:0009786)

Showing 1 to 10 of 30 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	GO:0072686	mitotic spindle(GO:0072686)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.3	1.1	GO:0044301	climbing fiber(GO:0044301)
0.0	1.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.1	0.8	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.7	GO:0072687	meiotic spindle(GO:0072687)
0.2	0.6	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	0.6	GO:0042585	germinal vesicle(GO:0042585)
0.1	0.5	GO:0071547	piP-body(GO:0071547)
0.1	0.5	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)

Showing 1 to 10 of 19 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	1.7	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	1.6	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	1.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.8	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.7	GO:0070569	uridylyltransferase activity(GO:0070569)
0.2	0.6	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.6	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.5	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)

Showing 1 to 10 of 16 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Showing 1 to 1 of 1 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	0.8	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling

Showing 1 to 6 of 6 entries

Results for MSX2

Z-value: 0.64

Motif logo

Transcription factors associated with MSX2

Activity-expression correlation:

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

No targets for MSX2

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: