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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MYB

Z-value: 4.37

Motif logo

Transcription factors associated with MYB

Gene Symbol Gene ID Gene Info
ENSG00000118513.14 MYB proto-oncogene, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBhg19_v2_chr6_+_135502466_1355024890.851.8e-06Click!

Activity profile of MYB motif

Sorted Z-values of MYB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
1.7 18.4 GO:0030259 lipid glycosylation(GO:0030259)
1.4 5.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.3 6.3 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
1.1 9.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.0 2.0 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.0 11.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.0 2.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.9 3.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.8 2.5 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.8 2.5 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.8 2.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.8 2.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 2.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.7 2.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.7 6.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.7 2.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.7 0.7 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.7 4.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 3.3 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.6 1.9 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.6 1.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.6 1.9 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.6 4.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.6 4.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.6 5.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.5 5.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.5 0.5 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.5 6.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 3.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.5 1.0 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.5 2.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.5 3.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.5 1.9 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.5 1.4 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.5 3.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.5 2.4 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.5 0.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5 9.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.5 1.8 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.5 3.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.4 1.8 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 3.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.4 4.9 GO:0006528 asparagine metabolic process(GO:0006528)
0.4 1.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.4 2.5 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.4 4.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.4 1.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.4 1.5 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.4 1.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.3 1.0 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.3 0.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 3.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.7 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 1.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.6 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 5.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 3.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 1.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.3 1.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 1.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 1.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.3 1.5 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.3 8.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 1.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 0.8 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.3 1.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.3 1.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 6.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 0.8 GO:0006147 guanine catabolic process(GO:0006147)
0.3 4.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 1.6 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.3 3.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.3 1.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.3 4.0 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3 2.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 6.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 4.6 GO:0090168 Golgi reassembly(GO:0090168)
0.3 0.3 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.3 1.0 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.2 3.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 3.9 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 1.0 GO:0036292 DNA rewinding(GO:0036292)
0.2 2.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.2 0.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 1.9 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.2 0.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 1.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 2.0 GO:0030242 pexophagy(GO:0030242)
0.2 4.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 2.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.9 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 0.6 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 9.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 2.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.4 GO:0007144 female meiosis I(GO:0007144)
0.2 0.6 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.2 1.6 GO:0060136 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.2 0.6 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.2 0.4 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.2 2.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 7.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.9 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 8.5 GO:0007099 centriole replication(GO:0007099)
0.2 1.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.2 GO:0046666 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.2 1.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.2 0.5 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.9 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 1.3 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 1.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.4 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.2 0.5 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 3.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.2 1.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 9.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 0.8 GO:0043686 co-translational protein modification(GO:0043686)
0.2 4.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 1.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 5.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 3.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.6 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 1.0 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 3.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 18.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 5.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.8 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 3.0 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:0060319 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) primitive erythrocyte differentiation(GO:0060319)
0.1 1.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.8 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 2.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 3.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 1.0 GO:0043570 meiotic mismatch repair(GO:0000710) maintenance of DNA repeat elements(GO:0043570)
0.1 3.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 1.6 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.7 GO:0000387 spliceosomal tri-snRNP complex assembly(GO:0000244) spliceosomal snRNP assembly(GO:0000387)
0.1 0.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 2.6 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1 2.7 GO:0033197 response to vitamin E(GO:0033197)
0.1 1.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 3.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.1 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.8 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 3.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 1.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.9 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.1 1.0 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 1.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.2 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 1.9 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.6 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 2.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.9 GO:0015867 ADP transport(GO:0015866) ATP transport(GO:0015867)
0.1 1.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 4.0 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.1 2.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 2.0 GO:0061387 regulation of axon extension(GO:0030516) regulation of extent of cell growth(GO:0061387)
0.1 2.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 1.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 2.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 2.5 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 2.6 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1 0.5 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 3.9 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.3 GO:0061304 cerebellum vasculature development(GO:0061300) retinal blood vessel morphogenesis(GO:0061304)
0.1 4.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 2.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 5.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.0 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.9 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.2 GO:0006090 pyruvate metabolic process(GO:0006090)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 7.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.0 GO:0032060 bleb assembly(GO:0032060)
0.1 2.5 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 2.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.8 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.5 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.3 GO:0010903 negative regulation of cytokine secretion involved in immune response(GO:0002740) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 1.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 1.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.5 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 2.1 GO:0090307 mitotic spindle assembly(GO:0090307)
0.1 0.2 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 2.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.5 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.8 GO:0051298 centrosome duplication(GO:0051298)
0.1 2.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.7 GO:0032025 response to cobalt ion(GO:0032025)
0.1 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.6 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 3.5 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 1.1 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 1.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 3.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0090209 negative regulation of triglyceride biosynthetic process(GO:0010868) negative regulation of triglyceride metabolic process(GO:0090209)
0.0 2.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.5 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 1.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.6 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 1.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.5 GO:0046461 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 4.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.3 GO:0045844 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 6.4 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 1.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 3.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.7 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 2.0 GO:0001510 RNA methylation(GO:0001510)
0.0 0.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.7 GO:0099536 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) synaptic signaling(GO:0099536) trans-synaptic signaling(GO:0099537)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.0 GO:1904029 regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 2.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 3.4 GO:0032355 response to estradiol(GO:0032355)
0.0 0.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 2.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 3.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.6 GO:0045595 regulation of cell differentiation(GO:0045595)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 2.5 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0010648 negative regulation of cell communication(GO:0010648) negative regulation of signaling(GO:0023057)
0.0 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0060346 sequestering of TGFbeta in extracellular matrix(GO:0035583) bone trabecula formation(GO:0060346)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0061571 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.6 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 1.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.7 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.4 GO:0043065 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.4 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 1.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.0 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702) mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 1.9 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.9 5.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.9 11.9 GO:0000796 condensin complex(GO:0000796)
0.9 6.1 GO:0098536 deuterosome(GO:0098536)
0.8 2.3 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.7 2.1 GO:0044609 DBIRD complex(GO:0044609)
0.7 2.8 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.6 4.0 GO:0035061 interchromatin granule(GO:0035061)
0.6 2.3 GO:0042585 germinal vesicle(GO:0042585)
0.6 2.3 GO:1990423 RZZ complex(GO:1990423)
0.5 1.5 GO:0034515 proteasome storage granule(GO:0034515)
0.5 5.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 1.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 1.7 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.7 GO:0005846 nuclear cap binding complex(GO:0005846)
0.4 2.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 1.6 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.4 2.3 GO:0071817 MMXD complex(GO:0071817)
0.4 1.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 1.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 1.4 GO:0005712 chiasma(GO:0005712)
0.4 2.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 3.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.4 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.3 1.4 GO:0001740 Barr body(GO:0001740)
0.3 9.3 GO:0036020 endolysosome membrane(GO:0036020)
0.3 4.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 13.9 GO:0034451 centriolar satellite(GO:0034451)
0.3 3.3 GO:0097255 R2TP complex(GO:0097255)
0.2 1.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 19.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 0.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 2.6 GO:0072687 meiotic spindle(GO:0072687)
0.2 2.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 2.2 GO:0005638 lamin filament(GO:0005638)
0.2 1.1 GO:0030496 midbody(GO:0030496)
0.2 4.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 0.8 GO:0055087 Ski complex(GO:0055087)
0.2 8.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 3.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.0 GO:0032301 MutSalpha complex(GO:0032301)
0.2 7.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.7 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 8.8 GO:0035371 microtubule plus-end(GO:0035371)
0.2 6.5 GO:0005921 gap junction(GO:0005921)
0.2 3.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 2.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 2.6 GO:0097227 sperm annulus(GO:0097227)
0.1 4.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.8 GO:0070652 HAUS complex(GO:0070652)
0.1 2.3 GO:0000124 SAGA complex(GO:0000124)
0.1 6.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.1 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 1.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.4 GO:0090543 Flemming body(GO:0090543)
0.1 16.8 GO:0005814 centriole(GO:0005814)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 5.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0032449 CBM complex(GO:0032449)
0.1 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.3 GO:0033010 paranodal junction(GO:0033010)
0.1 1.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.8 GO:0031105 septin complex(GO:0031105)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 6.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.8 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 2.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 4.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 11.5 GO:0000776 kinetochore(GO:0000776)
0.1 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.1 2.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.2 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 1.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 4.7 GO:0005871 kinesin complex(GO:0005871)
0.1 2.8 GO:0042383 sarcolemma(GO:0042383)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 4.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 7.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.1 GO:0071564 npBAF complex(GO:0071564)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 2.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.1 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.9 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 3.0 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 2.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 5.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0000800 lateral element(GO:0000800)
0.0 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0045095 keratin filament(GO:0045095)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.0 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 0.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 4.3 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 1.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 8.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588) zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0009986 cell surface(GO:0009986)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 5.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.5 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
1.0 4.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.9 7.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.9 6.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.9 2.6 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.8 2.5 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.8 2.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.7 2.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.7 6.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.7 4.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.6 2.6 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.6 1.9 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.6 1.9 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.6 3.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.6 1.9 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.6 2.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.5 1.6 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.5 3.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 2.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 1.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.7 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.4 1.3 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.4 3.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.4 1.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 1.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 1.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 3.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.3 1.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 1.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.3 1.0 GO:0032143 single thymine insertion binding(GO:0032143)
0.3 1.3 GO:0047708 biotinidase activity(GO:0047708)
0.3 1.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.3 3.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3 2.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.3 9.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 1.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 0.8 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 2.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 0.8 GO:0008892 guanine deaminase activity(GO:0008892)
0.3 1.6 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.3 3.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 7.0 GO:0008483 transaminase activity(GO:0008483)
0.3 12.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 2.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 1.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.2 2.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 1.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 3.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.9 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 0.7 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 1.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 14.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.6 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.2 0.8 GO:0003896 DNA primase activity(GO:0003896)
0.2 2.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.9 GO:0031208 POZ domain binding(GO:0031208)
0.2 0.7 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 1.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.5 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.7 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.5 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 2.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 3.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.6 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 2.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 2.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 6.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 2.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 2.3 GO:0008494 translation activator activity(GO:0008494)
0.1 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 3.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 2.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 4.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.7 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 5.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 3.0 GO:0005521 lamin binding(GO:0005521)
0.1 2.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 4.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 8.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 3.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 3.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0004096 catalase activity(GO:0004096)
0.0 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 4.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 7.7 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 2.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0032405 mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 10.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 4.0 GO:0004386 helicase activity(GO:0004386)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 2.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.4 GO:0046332 SMAD binding(GO:0046332)
0.0 4.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0005138 ciliary neurotrophic factor receptor binding(GO:0005127) interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 4.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 9.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 5.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 24.9 PID AURORA B PATHWAY Aurora B signaling
0.2 18.6 PID PLK1 PATHWAY PLK1 signaling events
0.2 12.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 11.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 11.2 PID P53 REGULATION PATHWAY p53 pathway
0.1 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 6.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.8 PID MYC PATHWAY C-MYC pathway
0.1 4.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 5.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.5 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 3.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 3.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 3.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 12.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 9.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 12.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 5.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 7.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 3.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 3.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 27.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 3.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 3.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.8 REACTOME KINESINS Genes involved in Kinesins
0.1 8.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 1.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 9.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 4.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 4.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 5.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 2.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 2.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 3.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 5.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 3.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport