ISMARA results: MYB

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MYB

Z-value: 4.37

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Transcription factors associated with MYB

Gene Symbol	Gene ID	Gene Info
MYB Ensembl NCBI GeneCards UniProt	ENSG00000118513.14	MYB proto-oncogene, transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MYB	hg19_v2_chr6_+_135502466_135502489	0.85	1.8e-06	Click!

Activity profile of MYB motif

Sorted Z-values of MYB motif

No targets for MYB

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	18.6	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
1.7	18.4	GO:0030259	lipid glycosylation(GO:0030259)
1.0	11.9	GO:0010032	meiotic chromosome condensation(GO:0010032)
2.2	11.1	GO:1903613	regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.5	9.9	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.2	9.9	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.2	9.6	GO:0033120	positive regulation of RNA splicing(GO:0033120)
1.1	9.5	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.2	8.5	GO:0007099	centriole replication(GO:0007099)
0.3	8.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)

Showing 1 to 10 of 372 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	19.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	16.8	GO:0005814	centriole(GO:0005814)
0.3	13.9	GO:0034451	centriolar satellite(GO:0034451)
0.9	11.9	GO:0000796	condensin complex(GO:0000796)
0.1	11.5	GO:0000776	kinetochore(GO:0000776)
0.3	9.3	GO:0036020	endolysosome membrane(GO:0036020)
0.2	8.8	GO:0035371	microtubule plus-end(GO:0035371)
1.4	8.2	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.2	8.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	8.1	GO:0048471	perinuclear region of cytoplasm(GO:0048471)

Showing 1 to 10 of 178 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.9	19.5	GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.2	14.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3	12.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	10.5	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3	9.3	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	9.1	GO:0005525	GTP binding(GO:0005525)
0.1	8.9	GO:0003777	microtubule motor activity(GO:0003777)
0.0	7.7	GO:0042393	histone binding(GO:0042393)
0.9	7.3	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.3	7.0	GO:0008483	transaminase activity(GO:0008483)

Showing 1 to 10 of 231 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	24.9	PID AURORA B PATHWAY	Aurora B signaling
0.2	18.6	PID PLK1 PATHWAY	PLK1 signaling events
0.2	12.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.2	11.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	11.2	PID P53 REGULATION PATHWAY	p53 pathway
0.1	6.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	5.7	PID LKB1 PATHWAY	LKB1 signaling events
0.1	4.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	4.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	3.8	PID MYC PATHWAY	C-MYC pathway

Showing 1 to 10 of 52 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	27.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	12.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.3	12.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3	9.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	9.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	8.8	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2	7.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.3	5.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	5.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	5.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane

Showing 1 to 10 of 83 entries

Results for MYB

Z-value: 4.37

Motif logo

Transcription factors associated with MYB

Activity-expression correlation:

Activity profile of MYB motif

Sorted Z-values of MYB motif

No targets for MYB

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: