Project
avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MYBL2
Z-value: 3.13
Motif logo
Transcription factors associated with MYBL2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MYBL2
|
ENSG00000101057.11 | MYB proto-oncogene like 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYBL2 | hg19_v2_chr20_+_42295745_42295797 | 0.64 | 2.4e-03 | Click! |
Activity profile of MYBL2 motif
Sorted Z-values of MYBL2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MYBL2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 9.1 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 1.4 | 4.3 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 1.0 | 3.0 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 0.9 | 2.7 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.8 | 2.5 | GO:1903567 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.8 | 3.3 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.8 | 4.1 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) |
| 0.7 | 2.2 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.7 | 2.8 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.7 | 2.8 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.7 | 2.1 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.7 | 8.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.7 | 2.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.7 | 4.0 | GO:0032954 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.6 | 1.9 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 0.5 | 1.6 | GO:2000224 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.5 | 5.1 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.5 | 2.5 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.4 | 4.1 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.4 | 3.2 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.4 | 1.6 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.4 | 3.9 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.4 | 2.3 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 0.4 | 1.5 | GO:0019056 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 0.4 | 1.1 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 0.4 | 1.4 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.3 | 1.4 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.3 | 1.4 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.3 | 1.3 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.3 | 2.6 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.3 | 0.9 | GO:0060829 | regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829) |
| 0.3 | 1.2 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.3 | 0.9 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 0.3 | 3.2 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 0.3 | 2.3 | GO:0060701 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.3 | 2.3 | GO:0032485 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.3 | 4.6 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.3 | 6.5 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.3 | 0.8 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.3 | 0.8 | GO:0007037 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.3 | 12.4 | GO:0007099 | centriole replication(GO:0007099) |
| 0.3 | 2.5 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.3 | 4.1 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.7 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.2 | 2.1 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.2 | 2.6 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.2 | 2.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.2 | 1.1 | GO:0042148 | strand invasion(GO:0042148) |
| 0.2 | 1.1 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.2 | 1.3 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.2 | 2.4 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 2.8 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.2 | 3.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.2 | 1.7 | GO:1902741 | interferon-alpha secretion(GO:0072642) telomerase RNA stabilization(GO:0090669) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.2 | 0.8 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.2 | 0.8 | GO:0019482 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) |
| 0.2 | 1.6 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.2 | 0.6 | GO:0002663 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.2 | 1.4 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 1.4 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.2 | 2.0 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.2 | 4.7 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.2 | 5.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.2 | 1.1 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.2 | 1.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.2 | 0.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.2 | 3.4 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.2 | 1.6 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.2 | 1.4 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.2 | 1.7 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.2 | 0.8 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
| 0.2 | 0.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 2.4 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.2 | 0.6 | GO:0072302 | negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.2 | 0.8 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.2 | 1.4 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.2 | 1.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 0.9 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 7.3 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.1 | 3.1 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 0.9 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) |
| 0.1 | 1.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 1.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 2.8 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 2.7 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 1.4 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.1 | 1.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 1.8 | GO:0015866 | ADP transport(GO:0015866) |
| 0.1 | 6.3 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.1 | 1.2 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.1 | 1.0 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.1 | 0.9 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.1 | 3.7 | GO:0000022 | mitotic spindle elongation(GO:0000022) |
| 0.1 | 3.5 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 2.6 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 1.4 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 1.6 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 0.6 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 2.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 1.3 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.1 | 2.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.6 | GO:0071733 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.1 | 2.2 | GO:0051493 | regulation of cytoskeleton organization(GO:0051493) |
| 0.1 | 1.0 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.1 | 0.8 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.1 | 2.1 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.1 | 0.3 | GO:0044209 | AMP salvage(GO:0044209) |
| 0.1 | 2.6 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.1 | 0.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 1.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.8 | GO:0051126 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
| 0.1 | 4.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 6.1 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.1 | 0.7 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.1 | 0.6 | GO:1901906 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 0.9 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.1 | 0.2 | GO:2000724 | positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724) |
| 0.1 | 0.7 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.1 | 2.1 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 1.9 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.1 | 0.5 | GO:1901536 | negative regulation of DNA demethylation(GO:1901536) |
| 0.1 | 1.9 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.1 | 0.8 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 0.3 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.1 | 3.9 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 0.6 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 1.3 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 0.1 | 1.1 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.1 | 2.3 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.8 | GO:0021564 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564) |
| 0.1 | 0.3 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.1 | 0.2 | GO:0046103 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.1 | 0.7 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
| 0.1 | 0.8 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 1.2 | GO:1901078 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 2.7 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 0.2 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 2.3 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.1 | 0.3 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.1 | 0.7 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.1 | 0.8 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 2.1 | GO:0034138 | toll-like receptor 3 signaling pathway(GO:0034138) |
| 0.1 | 2.3 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.1 | 0.6 | GO:1901189 | positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.1 | 1.2 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.4 | GO:0097694 | establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) |
| 0.1 | 2.1 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.1 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.1 | 0.3 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.1 | 1.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 1.4 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.2 | GO:1904772 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 0.1 | 0.3 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.1 | 0.9 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.5 | GO:1903772 | virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772) |
| 0.1 | 1.7 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 0.7 | GO:0009304 | transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304) |
| 0.1 | 0.9 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 1.4 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.4 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.6 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.1 | 0.9 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 0.1 | 4.1 | GO:0035307 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 0.1 | 0.2 | GO:0048075 | positive regulation of eye pigmentation(GO:0048075) |
| 0.1 | 0.5 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.9 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.1 | 2.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.2 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.1 | 0.4 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 1.0 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.1 | 0.9 | GO:0044803 | multi-organism membrane organization(GO:0044803) |
| 0.1 | 0.4 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.6 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.3 | GO:2000329 | peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329) |
| 0.0 | 0.5 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.0 | 0.7 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.9 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.5 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 1.0 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.6 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.0 | 0.4 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.0 | 0.1 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 0.0 | 0.4 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.7 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 1.3 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.3 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.0 | 0.4 | GO:0048549 | endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549) |
| 0.0 | 0.7 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.9 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.6 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.0 | 0.3 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 6.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 2.0 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.1 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
| 0.0 | 0.3 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.0 | 2.1 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
| 0.0 | 0.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.3 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.0 | 2.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 1.9 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.0 | 0.0 | GO:0006090 | pyruvate metabolic process(GO:0006090) |
| 0.0 | 0.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.6 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.3 | GO:0000076 | DNA replication checkpoint(GO:0000076) mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.4 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.4 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 0.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.2 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.0 | 1.6 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 1.9 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 4.4 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.0 | 0.9 | GO:0017038 | protein import(GO:0017038) |
| 0.0 | 0.6 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.0 | 0.2 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.7 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 2.3 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 0.6 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 1.0 | GO:0006625 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 1.0 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.0 | 1.0 | GO:2000816 | negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816) |
| 0.0 | 0.1 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 0.0 | 0.7 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 0.5 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.3 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.0 | 0.9 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.4 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 1.5 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 1.3 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 1.3 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.2 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
| 0.0 | 1.0 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.2 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.0 | 0.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.5 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.0 | 0.0 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.0 | 2.1 | GO:0030036 | actin cytoskeleton organization(GO:0030036) |
| 0.0 | 0.2 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.0 | 0.2 | GO:1903599 | positive regulation of mitophagy(GO:1903599) |
| 0.0 | 0.5 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.6 | GO:0034248 | regulation of translation(GO:0006417) regulation of cellular amide metabolic process(GO:0034248) |
| 0.0 | 0.1 | GO:1905097 | regulation of guanyl-nucleotide exchange factor activity(GO:1905097) |
| 0.0 | 1.1 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.0 | 1.3 | GO:0001510 | RNA methylation(GO:0001510) |
| 0.0 | 0.3 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 0.2 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.0 | 0.0 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.0 | 2.6 | GO:0007346 | regulation of mitotic cell cycle(GO:0007346) |
| 0.0 | 0.0 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.0 | 0.3 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 0.5 | GO:0060038 | cardiac muscle cell proliferation(GO:0060038) |
| 0.0 | 0.0 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.0 | 0.0 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.0 | 0.3 | GO:0030335 | positive regulation of cell migration(GO:0030335) |
| 0.0 | 0.4 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.4 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.3 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
| 0.0 | 0.1 | GO:1903445 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.0 | 0.1 | GO:0030952 | establishment or maintenance of cytoskeleton polarity(GO:0030952) |
| 0.0 | 0.2 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 0.0 | 0.7 | GO:0048635 | negative regulation of muscle organ development(GO:0048635) |
| 0.0 | 0.7 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.7 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.0 | 0.8 | GO:0001947 | heart looping(GO:0001947) |
| 0.0 | 0.0 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.0 | 0.6 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.0 | 0.1 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 2.0 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.4 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.0 | 0.2 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.0 | 0.1 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 2.2 | GO:0048738 | cardiac muscle tissue development(GO:0048738) |
| 0.0 | 0.3 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.1 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 1.3 | 3.9 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 1.0 | 7.7 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.8 | 2.4 | GO:0009346 | citrate lyase complex(GO:0009346) |
| 0.6 | 1.9 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.6 | 4.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.6 | 3.5 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.5 | 1.4 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 0.4 | 1.2 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.4 | 1.6 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.4 | 3.2 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.4 | 7.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.4 | 4.0 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.3 | 3.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.3 | 2.0 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.3 | 1.8 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.3 | 1.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.3 | 15.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.3 | 2.9 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.3 | 2.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.3 | 2.6 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.2 | 3.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 0.7 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.2 | 2.4 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.2 | 1.6 | GO:0000796 | condensin complex(GO:0000796) |
| 0.2 | 8.3 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.2 | 1.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 0.9 | GO:0019034 | viral replication complex(GO:0019034) |
| 0.2 | 0.7 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
| 0.2 | 1.1 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.2 | 1.3 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.2 | 0.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.2 | 1.6 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.2 | 0.6 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.1 | 1.6 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 2.7 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 4.1 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 1.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 1.1 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.1 | 1.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 1.8 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.1 | 2.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 0.7 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 0.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.1 | 2.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 0.4 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 1.5 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 0.4 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 1.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 3.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 3.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 0.4 | GO:0032449 | CBM complex(GO:0032449) |
| 0.1 | 1.0 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.1 | 2.1 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 0.5 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.1 | 9.4 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.1 | 4.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 0.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.4 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 2.0 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.8 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 3.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 0.8 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 1.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.7 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.1 | 0.8 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.1 | 8.2 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.9 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 0.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 0.9 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.9 | GO:0070187 | telosome(GO:0070187) |
| 0.1 | 4.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 0.4 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 1.6 | GO:0000776 | kinetochore(GO:0000776) |
| 0.1 | 0.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.6 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 1.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 1.8 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 4.1 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.1 | 1.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 6.0 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 6.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.9 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 4.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 3.1 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
| 0.0 | 0.2 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.0 | 0.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 1.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 2.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 1.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 4.1 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 2.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.1 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.5 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.8 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 1.0 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 1.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 1.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.8 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.7 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 3.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.8 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 1.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.1 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
| 0.0 | 2.9 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.2 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.3 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 1.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 2.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 7.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.2 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 2.9 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.1 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.0 | 1.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.0 | GO:0031213 | RSF complex(GO:0031213) |
| 0.0 | 2.0 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.2 | GO:0036020 | endolysosome membrane(GO:0036020) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 1.4 | 4.1 | GO:0032181 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.9 | 8.3 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.8 | 2.4 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 0.8 | 2.4 | GO:0003878 | ATP citrate synthase activity(GO:0003878) |
| 0.6 | 3.2 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.6 | 2.8 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.5 | 1.6 | GO:0047017 | geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017) |
| 0.5 | 1.6 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.5 | 2.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.5 | 1.4 | GO:0032143 | single guanine insertion binding(GO:0032142) single thymine insertion binding(GO:0032143) |
| 0.5 | 2.3 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.4 | 2.6 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 1.4 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.3 | 2.7 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.3 | 3.0 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.3 | 1.2 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 0.3 | 2.3 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.3 | 0.8 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.3 | 1.1 | GO:0002134 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.3 | 1.9 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.2 | 1.7 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
| 0.2 | 4.9 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.2 | 9.9 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 7.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.2 | 0.9 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
| 0.2 | 1.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.2 | 0.6 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
| 0.2 | 0.8 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.2 | 9.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.2 | 0.6 | GO:0004423 | iduronate-2-sulfatase activity(GO:0004423) |
| 0.2 | 1.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.2 | 2.4 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.2 | 0.7 | GO:0001026 | TFIIIB-type transcription factor activity(GO:0001026) |
| 0.2 | 1.3 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.2 | 0.6 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.2 | 4.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 0.6 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.2 | 4.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 2.7 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 2.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.1 | 1.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.1 | 1.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 2.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 0.6 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.1 | 0.9 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 6.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 8.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 6.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 1.8 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.1 | 2.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 1.6 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 6.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 2.2 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.7 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.1 | 1.7 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.1 | 0.9 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 0.6 | GO:0052841 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 2.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 1.7 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.1 | 0.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 0.3 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 0.1 | 1.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 0.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 1.0 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 6.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.5 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.1 | 0.9 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 2.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 0.3 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 1.2 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.1 | 1.0 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 1.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 3.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.6 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 2.1 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.8 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.9 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 0.3 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) |
| 0.1 | 7.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.5 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 0.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 0.6 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 0.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 1.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 0.3 | GO:0004096 | catalase activity(GO:0004096) |
| 0.1 | 0.6 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 1.1 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 0.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 0.4 | GO:0032405 | MutLalpha complex binding(GO:0032405) |
| 0.0 | 2.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.8 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 2.8 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 2.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.8 | GO:0070513 | death domain binding(GO:0070513) |
| 0.0 | 0.4 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.4 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 0.7 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 1.2 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 1.0 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 1.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.3 | GO:0005072 | transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) |
| 0.0 | 0.6 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.0 | 0.3 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 1.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 6.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 1.1 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.3 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.0 | 1.0 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 1.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 1.1 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.2 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.0 | 0.2 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.0 | 1.5 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.8 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 2.0 | GO:0015485 | cholesterol binding(GO:0015485) sterol binding(GO:0032934) |
| 0.0 | 0.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.5 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.0 | 3.6 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.6 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.3 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.4 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.2 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.0 | 0.2 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.0 | 1.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 4.6 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.3 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.3 | GO:0052658 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.0 | 0.0 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.0 | 1.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 2.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 0.0 | 2.3 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.1 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.0 | 1.3 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.2 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.1 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.0 | 0.1 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.0 | 0.3 | GO:0001055 | RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.1 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.0 | 0.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.0 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.9 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 1.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.6 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 0.4 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.3 | GO:0048487 | beta-tubulin binding(GO:0048487) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 20.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 16.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 0.9 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 1.4 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 1.3 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 5.6 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 3.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 1.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 2.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 4.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 2.4 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 2.7 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 3.1 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 3.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 3.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 2.1 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 6.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.3 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 2.2 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 2.0 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 1.5 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 2.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 3.6 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.8 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.9 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 3.3 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.7 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.9 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.4 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.2 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 4.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.6 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.4 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 0.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 15.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.3 | 6.8 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.3 | 9.1 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 7.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 21.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 2.5 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.1 | 5.2 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 2.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.5 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 4.5 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.1 | 3.0 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 4.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.3 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 0.3 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 0.8 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 3.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.8 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 2.9 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 3.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 1.4 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.1 | 2.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.7 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.1 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 2.2 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 2.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 1.4 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 1.3 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 1.1 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 2.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.3 | REACTOME ORC1 REMOVAL FROM CHROMATIN | Genes involved in Orc1 removal from chromatin |
| 0.0 | 3.5 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 1.0 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 1.4 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 1.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.6 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.4 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 2.5 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.8 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 2.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 3.6 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.0 | 1.1 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 1.2 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.7 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.7 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 0.0 | 0.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.7 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 0.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.6 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.0 | 0.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 4.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.4 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.8 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.5 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 1.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.0 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 0.4 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |