ISMARA results: MYF6

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MYF6

Z-value: 4.58

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Transcription factors associated with MYF6

Gene Symbol	Gene ID	Gene Info
MYF6 Ensembl NCBI GeneCards UniProt	ENSG00000111046.3	myogenic factor 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MYF6	hg19_v2_chr12_+_81101277_81101321	-0.34	1.4e-01	Click!

Activity profile of MYF6 motif

Sorted Z-values of MYF6 motif

No targets for MYF6

Network of associatons between targets according to the STRING database.

First level regulatory network of MYF6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	27.2	GO:1903779	regulation of cardiac conduction(GO:1903779)
4.4	17.5	GO:0042369	vitamin D catabolic process(GO:0042369)
1.5	17.5	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.8	15.6	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
3.7	14.9	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
0.2	14.7	GO:0038128	ERBB2 signaling pathway(GO:0038128)
4.7	14.2	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.6	12.8	GO:0071420	cellular response to histamine(GO:0071420)
0.2	11.7	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.8	11.3	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)

Showing 1 to 10 of 408 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	28.7	GO:0031966	mitochondrial membrane(GO:0031966)
0.1	25.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
1.9	16.8	GO:0035976	AP1 complex(GO:0035976)
0.6	15.6	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5	15.6	GO:1902711	GABA-A receptor complex(GO:1902711)
0.6	14.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	14.6	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	14.4	GO:0043204	perikaryon(GO:0043204)
0.1	13.2	GO:0005581	collagen trimer(GO:0005581)
0.0	10.3	GO:0016607	nuclear speck(GO:0016607)

Showing 1 to 10 of 148 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	20.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.2	18.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
3.5	17.5	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.4	17.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.7	15.6	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4	15.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
3.7	14.9	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.1	14.8	GO:0070700	BMP receptor binding(GO:0070700)
4.7	14.2	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1	14.1	GO:0005179	hormone activity(GO:0005179)

Showing 1 to 10 of 261 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	25.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	16.8	NABA COLLAGENS	Genes encoding collagen proteins
0.1	15.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	14.3	PID BMP PATHWAY	BMP receptor signaling
0.2	13.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	11.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	11.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	8.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	7.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	7.6	PID SHP2 PATHWAY	SHP2 signaling

Showing 1 to 10 of 64 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	23.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	20.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	19.4	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	17.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	16.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.5	15.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	14.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.3	12.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.4	11.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	10.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation

Showing 1 to 10 of 111 entries

Results for MYF6

Z-value: 4.58

Motif logo

Transcription factors associated with MYF6

Activity-expression correlation:

Activity profile of MYF6 motif

Sorted Z-values of MYF6 motif

No targets for MYF6

Network of associatons between targets according to the STRING database.

First level regulatory network of MYF6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: