avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
NFE2L1 Links Ensembl NCBI GeneCards UniProt	ENSG00000082641.11	nuclear factor, erythroid 2 like 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NFE2L1	hg19_v2_chr17_+_46125707_46125746	0.91	3.0e-08	Click!

View svg image
View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.0	19.9	GO:0051710	cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
2.3	27.8	GO:0070487	monocyte aggregation(GO:0070487)
2.3	6.9	GO:0035604	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
2.2	15.1	GO:0071461	cellular response to redox state(GO:0071461)
1.6	4.8	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.5	16.6	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
1.4	4.1	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
1.4	5.4	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.2	3.6	GO:2000283	regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.1	12.0	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0	6.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
1.0	5.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.9	2.8	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.9	2.8	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.9	2.8	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8	4.2	GO:0061528	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.7	2.2	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.7	2.0	GO:0008057	eye pigment granule organization(GO:0008057)
0.7	4.1	GO:0042335	cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.7	3.3	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.6	3.6	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5	3.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4	1.8	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4	3.5	GO:1901189	positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4	1.3	GO:0003147	neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4	1.3	GO:0007113	endomitotic cell cycle(GO:0007113)
0.4	4.3	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.4	2.7	GO:0051012	microtubule sliding(GO:0051012)
0.4	1.4	GO:1903979	negative regulation of microglial cell activation(GO:1903979)
0.4	2.5	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3	1.3	GO:0090096	regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3	2.6	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.3	3.7	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3	2.1	GO:1903232	melanosome assembly(GO:1903232)
0.3	4.4	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.3	0.9	GO:0072737	response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.3	1.9	GO:1903575	cornified envelope assembly(GO:1903575)
0.3	4.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.3	1.3	GO:0097403	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2	2.0	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2	2.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.2	1.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2	1.2	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2	2.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.2	0.9	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.2	0.7	GO:0030070	insulin processing(GO:0030070)
0.2	0.8	GO:0035397	helper T cell enhancement of adaptive immune response(GO:0035397)
0.2	2.6	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2	0.8	GO:0061582	intestinal epithelial cell migration(GO:0061582)
0.2	1.8	GO:0003383	apical constriction(GO:0003383)
0.2	0.8	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.2	0.8	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2	1.9	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2	2.3	GO:0021759	globus pallidus development(GO:0021759)
0.2	3.4	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2	0.6	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.2	0.6	GO:0002188	translation reinitiation(GO:0002188)
0.2	2.0	GO:2001181	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.2	0.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.2	0.9	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2	3.8	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.2	0.3	GO:0007288	sperm axoneme assembly(GO:0007288)
0.2	1.7	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	0.5	GO:0061055	myotome development(GO:0061055)
0.2	6.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2	0.5	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2	1.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.7	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	1.7	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1	1.8	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1	1.4	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	1.1	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	5.4	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	2.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	1.6	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	5.5	GO:0010575	positive regulation of vascular endothelial growth factor production(GO:0010575)
0.1	0.8	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0072579	molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1	1.6	GO:0051451	myoblast migration(GO:0051451)
0.1	0.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.3	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1	18.2	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.1	0.9	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	1.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.2	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.5	GO:1990569	UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1	1.6	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.1	1.0	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	1.9	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.9	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	2.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.3	GO:0019085	early viral transcription(GO:0019085)
0.1	0.6	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	1.0	GO:0015747	urate transport(GO:0015747)
0.1	3.1	GO:0045730	respiratory burst(GO:0045730)
0.1	0.4	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.1	2.9	GO:0045332	phospholipid translocation(GO:0045332)
0.1	2.1	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	2.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1	1.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.7	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.1	1.9	GO:0001946	lymphangiogenesis(GO:0001946)
0.1	0.7	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.1	0.4	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1	0.5	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1	1.5	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	3.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	1.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	0.6	GO:0009597	detection of virus(GO:0009597)
0.1	0.5	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.6	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1	0.6	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1	0.2	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	2.1	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.4	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	1.0	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.1	2.5	GO:0002576	platelet degranulation(GO:0002576)
0.1	4.3	GO:0018149	peptide cross-linking(GO:0018149)
0.1	1.4	GO:0051639	actin filament network formation(GO:0051639)
0.1	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	1.5	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	1.2	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	2.3	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1	0.6	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.5	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	0.6	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.1	0.3	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1	0.2	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	0.5	GO:1902808	positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	1.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	2.0	GO:0006491	N-glycan processing(GO:0006491)
0.0	1.7	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	2.7	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.7	GO:0033227	dsRNA transport(GO:0033227)
0.0	4.8	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	3.8	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.0	0.8	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.0	1.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.3	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	1.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.8	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.6	GO:0050808	synapse organization(GO:0050808)
0.0	0.8	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.2	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.9	GO:0097205	glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0	0.9	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.6	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.5	GO:0006477	protein sulfation(GO:0006477)
0.0	1.7	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.3	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.8	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.4	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.4	GO:0007097	nuclear migration(GO:0007097)
0.0	0.7	GO:0048535	lymph node development(GO:0048535)
0.0	0.3	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	1.5	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.6	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	1.8	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	1.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	3.6	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.4	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.1	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	1.9	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.5	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.2	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.0	0.8	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.7	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.4	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.5	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	1.5	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	1.4	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290)
0.0	0.3	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	1.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.4	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	11.1	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.0	0.4	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	0.3	GO:0046649	lymphocyte activation(GO:0046649)
0.0	0.1	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	1.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	2.3	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	2.5	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0097459	ferric iron import(GO:0033216) iron ion import into cell(GO:0097459) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) iron ion import across plasma membrane(GO:0098711)
0.0	0.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.3	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.1	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.6	GO:1901215	negative regulation of neuron death(GO:1901215)
0.0	0.1	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.2	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	0.4	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.9	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.5	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.4	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.5	16.6	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
2.5	19.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.9	2.8	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.8	4.2	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.8	4.0	GO:0031905	early endosome lumen(GO:0031905)
0.7	4.3	GO:0031673	H zone(GO:0031673)
0.5	2.0	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.5	1.4	GO:1990666	PCSK9-LDLR complex(GO:1990666)
0.5	1.8	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4	4.3	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4	3.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4	1.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3	0.3	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.3	3.1	GO:0032010	phagolysosome(GO:0032010)
0.2	5.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.2	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.2	5.4	GO:0005922	connexon complex(GO:0005922)
0.2	17.0	GO:0045095	keratin filament(GO:0045095)
0.2	5.8	GO:0005614	interstitial matrix(GO:0005614)
0.2	5.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	2.8	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	2.0	GO:0045179	apical cortex(GO:0045179)
0.1	1.8	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	1.3	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.5	GO:0097513	myosin II filament(GO:0097513)
0.1	0.6	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.1	1.5	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	4.7	GO:0097228	sperm principal piece(GO:0097228)
0.1	1.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	18.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	5.7	GO:0001533	cornified envelope(GO:0001533)
0.1	0.8	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	3.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	4.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	0.4	GO:0098839	postsynaptic density membrane(GO:0098839)
0.1	3.9	GO:0005605	basal lamina(GO:0005605)
0.1	0.6	GO:0005579	membrane attack complex(GO:0005579)
0.1	1.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	1.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	4.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	11.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.3	GO:0002177	manchette(GO:0002177)
0.1	0.9	GO:0032797	SMN complex(GO:0032797)
0.1	2.9	GO:0016592	mediator complex(GO:0016592)
0.1	1.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.8	GO:0005869	dynactin complex(GO:0005869)
0.0	0.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	3.5	GO:0005771	multivesicular body(GO:0005771)
0.0	0.5	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	15.9	GO:0060076	excitatory synapse(GO:0060076)
0.0	1.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	2.4	GO:1990391	DNA repair complex(GO:1990391)
0.0	2.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.0	0.5	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.6	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	2.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.4	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.6	GO:0042599	lamellar body(GO:0042599)
0.0	1.3	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.7	GO:0032040	small-subunit processome(GO:0032040)
0.0	2.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	3.1	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.5	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.5	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.8	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0016013	syntrophin complex(GO:0016013)
0.0	1.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.1	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	2.4	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	1.8	GO:0005796	Golgi lumen(GO:0005796)
0.0	2.1	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.9	GO:0031519	PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	15.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2	3.6	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
1.0	4.0	GO:0035651	AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.9	12.0	GO:0047035	alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.8	4.2	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7	4.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6	6.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.5	5.4	GO:0045545	syndecan binding(GO:0045545)
0.5	13.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.5	2.0	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.5	18.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.4	2.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.4	16.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4	2.7	GO:0070728	leucine binding(GO:0070728)
0.4	1.9	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.4	1.9	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4	3.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	1.3	GO:0061714	folic acid receptor activity(GO:0061714)
0.3	2.8	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.3	1.2	GO:0015616	DNA translocase activity(GO:0015616)
0.3	4.9	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	0.9	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.2	0.9	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2	0.9	GO:0010348	lithium:proton antiporter activity(GO:0010348)
0.2	1.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.2	0.8	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.2	3.3	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.2	18.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	5.7	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2	2.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	1.4	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2	3.5	GO:0000150	recombinase activity(GO:0000150)
0.2	3.9	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	4.2	GO:0015643	toxic substance binding(GO:0015643)
0.2	3.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.5	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.2	1.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	2.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	18.5	GO:0001618	virus receptor activity(GO:0001618)
0.1	1.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	3.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.8	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	0.4	GO:0061598	molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1	0.7	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	2.1	GO:0017166	vinculin binding(GO:0017166)
0.1	4.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.9	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	5.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	2.0	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	1.0	GO:0005123	death receptor binding(GO:0005123)
0.1	4.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	2.3	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	0.5	GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1	3.6	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	1.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	2.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.8	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	22.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	1.7	GO:0032052	bile acid binding(GO:0032052)
0.1	1.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.6	GO:0046790	virion binding(GO:0046790)
0.1	0.5	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1	1.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	0.5	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	0.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	2.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	2.8	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.6	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	1.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.8	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	0.4	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.1	1.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.5	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.7	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	1.9	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.3	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	0.2	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.8	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	1.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	2.1	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	1.3	GO:0016208	AMP binding(GO:0016208)
0.0	2.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	3.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.3	GO:0003777	microtubule motor activity(GO:0003777)
0.0	1.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.6	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.5	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.0	1.8	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	1.9	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	1.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	1.8	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	1.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	1.7	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	1.0	GO:0032452	histone demethylase activity(GO:0032452)
0.0	1.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	2.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	1.8	GO:0005080	protein kinase C binding(GO:0005080)
0.0	2.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.2	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.0	7.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	4.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.6	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.7	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	1.5	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.6	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.4	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.2	GO:0005507	copper ion binding(GO:0005507)
0.0	1.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	1.5	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	3.5	GO:0042393	histone binding(GO:0042393)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	1.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.2	GO:0044325	ion channel binding(GO:0044325)
0.0	1.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	27.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	17.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	8.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	17.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	5.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	9.5	PID FGF PATHWAY	FGF signaling pathway
0.1	2.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	6.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	2.8	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.4	PID RAS PATHWAY	Regulation of Ras family activation
0.1	4.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	4.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	3.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	3.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	2.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	3.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	3.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	2.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	18.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	7.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.3	2.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	5.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	2.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	3.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	3.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	6.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	2.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	4.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	17.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	2.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	2.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	3.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	6.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.8	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	3.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	3.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.5	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.1	1.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	15.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	5.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	3.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	1.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	3.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	3.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	7.0	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	1.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	3.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	3.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall