ISMARA results: NFIL3

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFIL3

Z-value: 1.03

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Transcription factors associated with NFIL3

Gene Symbol	Gene ID	Gene Info
NFIL3 Ensembl NCBI GeneCards UniProt	ENSG00000165030.3	nuclear factor, interleukin 3 regulated

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NFIL3	hg19_v2_chr9_-_94186131_94186174	0.10	6.9e-01	Click!

Activity profile of NFIL3 motif

Sorted Z-values of NFIL3 motif

No targets for NFIL3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	1.3	GO:0006953	acute-phase response(GO:0006953)
0.2	0.9	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.9	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.8	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.0	0.8	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.0	0.8	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.7	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.6	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)

Showing 1 to 10 of 203 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0001533	cornified envelope(GO:0001533)
0.1	0.9	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.0	0.8	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.8	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.8	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2	0.7	GO:1990742	microvesicle(GO:1990742)
0.1	0.6	GO:0097179	protease inhibitor complex(GO:0097179)
0.0	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.6	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	0.5	GO:0070876	SOSS complex(GO:0070876)

Showing 1 to 10 of 62 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	1.4	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.9	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3	0.8	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.3	0.8	GO:0002113	interleukin-33 binding(GO:0002113)
0.1	0.8	GO:0071723	lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.0	0.8	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.8	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.7	GO:0089720	caspase binding(GO:0089720)

Showing 1 to 10 of 126 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.3	PID TRAIL PATHWAY	TRAIL signaling pathway
1.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Showing 1 to 5 of 5 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	1.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.9	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway

Showing 1 to 10 of 26 entries

Results for NFIL3

Z-value: 1.03

Motif logo

Transcription factors associated with NFIL3

Activity-expression correlation:

Activity profile of NFIL3 motif

Sorted Z-values of NFIL3 motif

No targets for NFIL3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: