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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFIL3

Z-value: 1.03

Motif logo

Transcription factors associated with NFIL3

Gene Symbol Gene ID Gene Info
ENSG00000165030.3 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIL3hg19_v2_chr9_-_94186131_941861740.106.9e-01Click!

Activity profile of NFIL3 motif

Sorted Z-values of NFIL3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.3 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 1.8 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.6 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.2 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.1 0.1 GO:0032649 interferon-gamma production(GO:0032609) regulation of interferon-gamma production(GO:0032649) positive regulation of interferon-gamma production(GO:0032729)
0.1 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.4 GO:0035234 smooth muscle adaptation(GO:0014805) ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.4 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.1 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.6 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0046066 dGDP metabolic process(GO:0046066)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:1901214 regulation of neuron death(GO:1901214)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650)
0.0 0.1 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.0 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.0 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 1.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.0 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.4 GO:1903651 positive regulation of cytoplasmic transport(GO:1903651)
0.0 0.1 GO:0070487 monocyte aggregation(GO:0070487)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.0 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.0 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.2 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990742 microvesicle(GO:1990742)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 0.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.8 GO:0071723 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.1 0.6 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.7 GO:0005501 retinoid binding(GO:0005501)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.0 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix