Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for NHLH1

Z-value: 1.66

Motif logo

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_1603368680.029.3e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.9 4.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.9 2.6 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.9 2.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.8 2.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.7 2.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.7 3.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.7 2.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.5 1.6 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 1.5 GO:0006059 hexitol metabolic process(GO:0006059)
0.5 4.1 GO:0007386 compartment pattern specification(GO:0007386)
0.5 2.0 GO:0014060 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) epinephrine secretion(GO:0048242)
0.5 1.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 2.7 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.4 3.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4 1.7 GO:0035690 cellular response to drug(GO:0035690)
0.4 1.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 1.8 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 1.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 1.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.3 1.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.3 0.9 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 2.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 1.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 1.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 2.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.3 0.8 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.2 0.7 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2 0.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.7 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 2.0 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 1.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.2 2.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.9 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.0 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.2 1.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.7 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 0.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 1.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 2.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 1.5 GO:0030242 pexophagy(GO:0030242)
0.2 1.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 1.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.2 0.5 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 1.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.5 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.3 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 4.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.9 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 1.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 1.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.4 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 1.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.5 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.3 GO:0035696 monocyte extravasation(GO:0035696) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 1.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 2.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.4 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.3 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 2.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0060214 endocardium formation(GO:0060214)
0.1 2.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:1901185 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) regulation of epidermal growth factor-activated receptor activity(GO:0007176) negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1 1.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.8 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.7 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 2.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 3.2 GO:0000732 strand displacement(GO:0000732)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 0.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.9 GO:0021756 striatum development(GO:0021756)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 1.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:0015853 adenine transport(GO:0015853)
0.1 1.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.2 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 2.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.3 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0072240 ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240)
0.0 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.7 GO:0019722 calcium-mediated signaling(GO:0019722) second-messenger-mediated signaling(GO:0019932)
0.0 0.2 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) detection of chemical stimulus involved in sensory perception of pain(GO:0050968) response to capsazepine(GO:1901594)
0.0 0.3 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.6 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.8 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 1.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 7.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0001764 neuron migration(GO:0001764)
0.0 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.8 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.7 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 2.3 GO:1903307 positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 1.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 2.6 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 1.0 GO:0097502 mannosylation(GO:0097502)
0.0 0.6 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0010959 regulation of metal ion transport(GO:0010959)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.6 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.3 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 1.0 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.0 GO:0046823 negative regulation of nucleocytoplasmic transport(GO:0046823)
0.0 0.4 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.1 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 1.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 2.0 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.4 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.6 GO:0061008 liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 2.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.4 1.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.4 3.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 1.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 1.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.3 7.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.5 GO:0031262 Ndc80 complex(GO:0031262)
0.2 2.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 2.6 GO:0005883 neurofilament(GO:0005883)
0.2 0.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 1.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 4.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:1990393 3M complex(GO:1990393)
0.1 0.3 GO:0030686 90S preribosome(GO:0030686)
0.1 1.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.9 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.2 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 4.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 1.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 3.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.2 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.7 2.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.5 2.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.5 1.6 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.5 3.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 2.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 2.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.4 1.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 2.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 1.5 GO:0004335 galactokinase activity(GO:0004335)
0.3 3.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 0.9 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 2.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.3 2.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 1.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 1.9 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.2 4.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 0.5 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 0.5 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.9 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 3.8 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0030984 kininogen binding(GO:0030984)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 2.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 1.6 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 1.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 1.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 3.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.3 GO:0016174 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 3.6 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0019207 kinase regulator activity(GO:0019207)
0.0 0.0 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 6.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 1.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 3.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 3.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 2.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 6.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.9 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation