avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
NR1H4
|
ENSG00000012504.9 | nuclear receptor subfamily 1 group H member 4 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NR1H4 | hg19_v2_chr12_+_100897130_100897231 | -0.55 | 1.1e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0048597 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
0.7 | 2.7 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
0.6 | 1.9 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
0.4 | 3.3 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.3 | 2.8 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.3 | 2.5 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.3 | 1.8 | GO:0032571 | response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523) |
0.2 | 0.7 | GO:0060532 | bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) |
0.2 | 0.7 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
0.2 | 1.4 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.2 | 1.6 | GO:1901189 | positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
0.2 | 3.4 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
0.2 | 1.9 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.1 | 0.5 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
0.1 | 1.0 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
0.1 | 0.7 | GO:2000784 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
0.1 | 0.6 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
0.1 | 2.4 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
0.1 | 9.2 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.1 | 0.2 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
0.1 | 0.8 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.1 | 0.6 | GO:0098728 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.1 | 0.2 | GO:0046416 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-amino acid metabolic process(GO:0046416) |
0.1 | 2.4 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.3 | GO:0002729 | positive regulation of natural killer cell cytokine production(GO:0002729) |
0.1 | 0.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.1 | 0.4 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.1 | 0.8 | GO:0030856 | regulation of epithelial cell differentiation(GO:0030856) |
0.1 | 1.1 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.1 | 1.5 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.4 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.0 | 0.6 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.0 | 0.1 | GO:0050894 | determination of affect(GO:0050894) |
0.0 | 1.2 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
0.0 | 1.2 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
0.0 | 0.3 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
0.0 | 1.0 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
0.0 | 0.7 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
0.0 | 0.4 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.0 | 1.0 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 1.0 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
0.0 | 0.7 | GO:0048243 | norepinephrine secretion(GO:0048243) |
0.0 | 1.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.1 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
0.0 | 1.6 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
0.0 | 0.3 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.0 | 1.6 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.0 | 2.2 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 11.3 | GO:0016197 | endosomal transport(GO:0016197) |
0.0 | 2.8 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.9 | GO:1902186 | regulation of viral release from host cell(GO:1902186) |
0.0 | 1.4 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.0 | 0.1 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
0.0 | 2.4 | GO:0006305 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
0.0 | 0.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.7 | GO:0015695 | organic cation transport(GO:0015695) |
0.0 | 0.3 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.0 | 2.2 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.3 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
0.0 | 0.2 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
0.0 | 0.4 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.0 | 0.1 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
0.0 | 0.5 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.0 | 1.2 | GO:0001510 | RNA methylation(GO:0001510) |
0.0 | 0.6 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
0.0 | 0.2 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.0 | 0.1 | GO:0035524 | proline transmembrane transport(GO:0035524) |
0.0 | 0.0 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 1.1 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
0.0 | 0.1 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
0.0 | 0.2 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 8.4 | GO:0070876 | SOSS complex(GO:0070876) |
0.6 | 1.9 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
0.2 | 2.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 1.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 1.2 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
0.1 | 1.6 | GO:0071986 | Ragulator complex(GO:0071986) |
0.1 | 0.3 | GO:0005745 | m-AAA complex(GO:0005745) |
0.1 | 2.9 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 0.5 | GO:0097513 | myosin II filament(GO:0097513) |
0.1 | 0.5 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
0.1 | 0.6 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.1 | 1.0 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 0.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 2.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 1.3 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 1.7 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.7 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 3.3 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.4 | GO:0032797 | SMN complex(GO:0032797) |
0.0 | 0.8 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.3 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.0 | 3.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 1.9 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.2 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.0 | 0.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 1.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 1.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
0.0 | 1.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.7 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 1.8 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 12.0 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 1.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.1 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 11.1 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.3 | 2.7 | GO:0045545 | syndecan binding(GO:0045545) |
0.2 | 1.4 | GO:0017161 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.2 | 2.0 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
0.2 | 2.8 | GO:0008199 | ferric iron binding(GO:0008199) |
0.1 | 0.7 | GO:0010736 | serum response element binding(GO:0010736) |
0.1 | 2.4 | GO:0051400 | BH domain binding(GO:0051400) |
0.1 | 0.6 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 1.1 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 0.8 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
0.1 | 1.5 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
0.1 | 1.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.1 | 1.6 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 2.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 3.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 2.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 1.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 0.7 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.0 | 1.0 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 8.0 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 1.6 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 0.1 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
0.0 | 1.0 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 1.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 1.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 0.2 | GO:0050436 | microfibril binding(GO:0050436) |
0.0 | 2.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.3 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.8 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.7 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.0 | 0.1 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.0 | 0.6 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.8 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 1.2 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
0.0 | 0.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 1.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 2.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.3 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 1.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.4 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 6.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
0.1 | 3.1 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
0.0 | 13.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
0.0 | 0.7 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.8 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.0 | 3.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 1.6 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 0.7 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.8 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
0.0 | 0.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 0.4 | PID ARF 3PATHWAY | Arf1 pathway |
0.0 | 0.8 | PID BCR 5PATHWAY | BCR signaling pathway |
0.0 | 1.3 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.4 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
0.1 | 2.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 1.9 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 1.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.1 | 1.6 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 1.2 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.1 | 1.4 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 2.6 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
0.0 | 1.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 2.4 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
0.0 | 1.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 2.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 0.9 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.8 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 1.0 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.7 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.0 | 2.5 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
0.0 | 1.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 2.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |