ISMARA results: NR1I3

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR1I3

Z-value: 0.67

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Transcription factors associated with NR1I3

Gene Symbol	Gene ID	Gene Info
NR1I3 Ensembl NCBI GeneCards UniProt	ENSG00000143257.7	nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NR1I3	hg19_v2_chr1_-_161207875_161207901	-0.25	2.8e-01	Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

No targets for NR1I3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0	1.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	1.2	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	1.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	1.1	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.6	GO:0030903	notochord development(GO:0030903)
0.1	0.5	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0	0.5	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.5	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)

Showing 1 to 10 of 32 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	GO:0071817	MMXD complex(GO:0071817)
0.3	1.1	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.4	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.3	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.2	GO:0036156	inner dynein arm(GO:0036156)

Showing 1 to 10 of 13 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	1.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.7	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.2	0.5	GO:0043337	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1	0.5	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.4	GO:0005046	KDEL sequence binding(GO:0005046)
0.1	0.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.3	GO:0004689	phosphorylase kinase activity(GO:0004689)

Showing 1 to 10 of 15 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
2.2	PID IL23 PATHWAY	IL23-mediated signaling events
1.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4	PID ARF 3PATHWAY	Arf1 pathway

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)

Showing 1 to 6 of 6 entries

Results for NR1I3

Z-value: 0.67

Motif logo

Transcription factors associated with NR1I3

Activity-expression correlation:

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

No targets for NR1I3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: