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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR3C1

Z-value: 2.73

Motif logo

Transcription factors associated with NR3C1

Gene Symbol Gene ID Gene Info
ENSG00000113580.10 nuclear receptor subfamily 3 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR3C1hg19_v2_chr5_-_142782862_142782894-0.595.7e-03Click!

Activity profile of NR3C1 motif

Sorted Z-values of NR3C1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR3C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.9 11.6 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
1.4 9.8 GO:0030035 microspike assembly(GO:0030035)
1.4 4.1 GO:0046521 sphingoid catabolic process(GO:0046521)
1.4 5.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.3 3.9 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
1.2 9.9 GO:0036018 cellular response to erythropoietin(GO:0036018)
1.1 6.9 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.1 5.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.9 0.9 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.9 6.9 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.8 4.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8 1.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.7 2.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.7 2.9 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.7 2.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.7 4.6 GO:0071461 cellular response to redox state(GO:0071461)
0.6 1.8 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.6 2.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.5 5.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 19.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 2.6 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 6.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.5 1.9 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5 1.4 GO:0050904 diapedesis(GO:0050904)
0.5 1.8 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 2.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 3.0 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.4 2.4 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 2.4 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 3.2 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.4 2.4 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.4 1.2 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.4 1.2 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
0.4 1.8 GO:0016240 autophagosome docking(GO:0016240)
0.4 1.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.4 3.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.3 2.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.3 3.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.3 6.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.3 1.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 1.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 1.6 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 9.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 0.9 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 1.2 GO:0006408 snRNA export from nucleus(GO:0006408)
0.3 2.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.3 3.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.5 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 5.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.3 1.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.7 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.3 0.9 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 1.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.3 1.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3 2.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.3 1.4 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.3 1.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 0.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.3 1.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 1.4 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 1.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.3 1.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 1.6 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.3 6.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.3 2.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.3 1.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 0.8 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.3 3.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.3 1.8 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2 3.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 8.2 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 1.0 GO:0033594 response to hydroxyisoflavone(GO:0033594) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 1.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 1.4 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.2 1.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.2 1.6 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 1.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.2 2.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 0.9 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 0.6 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 1.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.4 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 1.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 1.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 2.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.0 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.2 5.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.6 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.2 1.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 1.9 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.5 GO:0021564 vagus nerve development(GO:0021564)
0.2 4.8 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.2 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 11.7 GO:0018149 peptide cross-linking(GO:0018149)
0.2 2.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.2 5.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.1 1.2 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 8.9 GO:0043616 keratinocyte proliferation(GO:0043616)
0.1 2.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.9 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.4 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.5 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.1 1.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.4 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 1.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 3.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.6 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 1.5 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.1 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 3.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 3.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 2.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 3.5 GO:0002076 osteoblast development(GO:0002076)
0.1 1.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.4 GO:0097475 motor neuron migration(GO:0097475)
0.1 2.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.0 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 1.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.5 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.2 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 2.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 2.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 2.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.7 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.5 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 1.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.8 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 1.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 3.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 4.2 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.3 GO:0090677 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 1.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.8 GO:0015695 organic cation transport(GO:0015695)
0.1 0.6 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 1.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 0.9 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.7 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 1.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 2.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.8 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.1 0.2 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 4.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 2.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 4.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 2.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 3.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.1 0.5 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 2.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 2.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.4 GO:0035900 isocitrate metabolic process(GO:0006102) response to isolation stress(GO:0035900)
0.1 1.5 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:2000667 positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.5 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.5 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.5 GO:0008544 epidermis development(GO:0008544)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0060180 female mating behavior(GO:0060180)
0.0 0.6 GO:0007512 adult heart development(GO:0007512)
0.0 3.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 1.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.4 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 1.8 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 1.1 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 4.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 1.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 2.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.3 GO:0016577 histone demethylation(GO:0016577)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 4.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.6 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0060349 bone morphogenesis(GO:0060349)
0.0 3.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.8 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.5 GO:0042476 odontogenesis(GO:0042476)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 3.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0097503 sialylation(GO:0097503)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.8 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:0045329 carnitine metabolic process(GO:0009437) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.8 GO:0051180 vitamin transport(GO:0051180)
0.0 0.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 2.2 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0006612 protein targeting to membrane(GO:0006612) cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.0 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:1901031 regulation of response to reactive oxygen species(GO:1901031)
0.0 0.0 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0061458 reproductive system development(GO:0061458)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0001501 skeletal system development(GO:0001501)
0.0 0.1 GO:0061744 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0003170 heart valve development(GO:0003170)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 3.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.0 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.3 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.2 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 1.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.0 GO:0009750 response to fructose(GO:0009750)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 1.3 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.9 10.1 GO:0005610 laminin-5 complex(GO:0005610)
0.6 4.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.5 4.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 4.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.5 1.5 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.4 2.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 5.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.4 1.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 6.3 GO:0031209 SCAR complex(GO:0031209)
0.3 2.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.3 1.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 9.9 GO:0030056 hemidesmosome(GO:0030056)
0.3 1.9 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3 3.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 0.9 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 1.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.3 1.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 1.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 18.0 GO:0001533 cornified envelope(GO:0001533)
0.2 2.5 GO:0061574 ASAP complex(GO:0061574)
0.2 3.8 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 6.3 GO:0005922 connexon complex(GO:0005922)
0.2 0.4 GO:0005902 microvillus(GO:0005902)
0.2 1.8 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 0.6 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 3.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.9 GO:0005833 hemoglobin complex(GO:0005833)
0.2 5.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 0.6 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 2.1 GO:0001939 female pronucleus(GO:0001939)
0.1 2.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 1.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 4.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 2.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 2.5 GO:0097386 glial cell projection(GO:0097386)
0.1 0.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.4 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.8 GO:0005921 gap junction(GO:0005921)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:0005713 recombination nodule(GO:0005713)
0.1 2.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 13.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 6.3 GO:0015030 Cajal body(GO:0015030)
0.1 7.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 1.1 GO:0030914 STAGA complex(GO:0030914)
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.4 GO:0005771 multivesicular body(GO:0005771)
0.1 2.2 GO:0071437 invadopodium(GO:0071437)
0.1 0.2 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 2.2 GO:0031105 septin complex(GO:0031105)
0.1 4.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.9 GO:0070938 contractile ring(GO:0070938)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 3.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.9 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 3.5 GO:0005811 lipid particle(GO:0005811)
0.0 6.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0014704 intercalated disc(GO:0014704)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 4.6 GO:0001726 ruffle(GO:0001726)
0.0 2.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 5.0 GO:0045121 membrane raft(GO:0045121)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.6 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7 5.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.7 2.6 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.6 5.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.6 1.8 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.6 4.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 4.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 2.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 2.4 GO:0052848 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4 2.4 GO:0017153 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.4 1.6 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 4.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.4 5.3 GO:0046870 cadmium ion binding(GO:0046870)
0.3 1.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.3 4.4 GO:0019534 toxin transporter activity(GO:0019534)
0.3 1.7 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 4.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3 2.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 1.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 5.8 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 1.2 GO:0001855 complement component C4b binding(GO:0001855)
0.3 1.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 1.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 6.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 2.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 3.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 3.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 2.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 5.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 0.8 GO:0008431 vitamin E binding(GO:0008431)
0.2 11.4 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 2.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.6 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.4 GO:0004771 sterol esterase activity(GO:0004771)
0.2 2.7 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 0.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.5 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 2.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.8 GO:0089720 caspase binding(GO:0089720)
0.2 2.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.6 GO:0045159 myosin II binding(GO:0045159)
0.1 2.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 1.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 1.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 4.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 1.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.2 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 4.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 5.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 5.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 5.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.5 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 17.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.6 GO:0043295 glutathione binding(GO:0043295)
0.1 0.4 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.6 GO:0055103 ligase regulator activity(GO:0055103)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 3.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 2.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 2.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 7.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 13.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.7 GO:0017166 vinculin binding(GO:0017166)
0.0 3.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.8 GO:0000150 recombinase activity(GO:0000150)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.9 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 7.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 5.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.0 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 3.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0004386 helicase activity(GO:0004386)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 5.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 10.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 4.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 10.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 16.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 6.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 3.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.1 PID IL3 PATHWAY IL3-mediated signaling events
0.1 10.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 9.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 8.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.1 PID EPO PATHWAY EPO signaling pathway
0.1 6.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 6.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 4.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 13.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 4.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 3.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 6.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 4.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 29.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 5.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 5.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 9.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 4.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 3.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 9.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 5.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 4.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 5.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 3.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 2.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 4.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 4.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle