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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR6A1

Z-value: 1.17

Motif logo

Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
ENSG00000148200.12 nuclear receptor subfamily 6 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v2_chr9_-_127358087_127358170-0.723.0e-04Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 1.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.6 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 1.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 1.0 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 0.6 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.4 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.4 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.0 GO:0007620 copulation(GO:0007620)
0.1 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.5 GO:0034720 T cell antigen processing and presentation(GO:0002457) histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.5 GO:0060316 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:0003014 renal system process(GO:0003014)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0046959 habituation(GO:0046959)
0.0 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.6 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 1.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:0035573 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.3 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0061055 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 1.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.6 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.5 1.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 0.5 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.4 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.3 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.5 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995) PTB domain binding(GO:0051425)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis