ISMARA results: OSR1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OSR1_OSR2

Z-value: 0.69

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Transcription factors associated with OSR1_OSR2

Gene Symbol	Gene ID	Gene Info
OSR1 Ensembl NCBI GeneCards UniProt	ENSG00000143867.5	odd-skipped related transcription factor 1
OSR2 Ensembl NCBI GeneCards UniProt	ENSG00000164920.5	odd-skipped related transciption factor 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
OSR2	hg19_v2_chr8_+_99956759_99956887	0.51	2.1e-02	Click!
OSR1	hg19_v2_chr2_-_19558373_19558414	0.43	6.1e-02	Click!

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

No targets for OSR1_OSR2

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.6	1.8	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1	1.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.4	1.1	GO:0016488	sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.0	1.1	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	1.0	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.2	0.8	GO:1901143	insulin catabolic process(GO:1901143)
0.2	0.8	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0	0.7	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2	0.5	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)

Showing 1 to 10 of 44 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4	1.8	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.1	1.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.8	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.8	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.5	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	0.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.3	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)

Showing 1 to 10 of 18 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.3	1.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1	1.2	GO:0043515	kinetochore binding(GO:0043515)
0.4	1.1	GO:0045550	geranylgeranyl reductase activity(GO:0045550)
0.0	1.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.2	1.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3	0.8	GO:0031626	beta-endorphin binding(GO:0031626)
0.0	0.8	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.7	GO:0019894	kinesin binding(GO:0019894)
0.2	0.5	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)

Showing 1 to 10 of 34 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
2.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
2.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.8	PID AURORA B PATHWAY	Aurora B signaling

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	2.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Showing 1 to 6 of 6 entries

Results for OSR1_OSR2

Z-value: 0.69

Motif logo

Transcription factors associated with OSR1_OSR2

Activity-expression correlation:

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

No targets for OSR1_OSR2

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: