ISMARA results: OTX1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OTX1

Z-value: 0.43

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Transcription factors associated with OTX1

Gene Symbol	Gene ID	Gene Info
OTX1 Ensembl NCBI GeneCards UniProt	ENSG00000115507.5	orthodenticle homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
OTX1	hg19_v2_chr2_+_63277927_63277938	0.21	3.8e-01	Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

No targets for OTX1

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:1903575	cornified envelope assembly(GO:1903575)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.2	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0019254	amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:2000395	regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)

Showing 1 to 10 of 17 entries

Gene overrepresentation in cellular_component category:

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Total log-likelihood	Term	Description
0.1	GO:1990923	PET complex(GO:1990923)
0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	GO:0005927	muscle tendon junction(GO:0005927)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.2	GO:0097259	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0031780	corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0097689	iron channel activity(GO:0097689)

Showing 1 to 10 of 12 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade

Showing 1 to 1 of 1 entries

Results for OTX1

Z-value: 0.43

Motif logo

Transcription factors associated with OTX1

Activity-expression correlation:

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

No targets for OTX1

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category: