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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OTX1

Z-value: 0.43

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
ENSG00000115507.5 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_632779380.213.8e-01Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0002879 leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.1 GO:1900004 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0097689 iron channel activity(GO:0097689)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade