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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX7_NOBOX

Z-value: 1.31

Motif logo

Transcription factors associated with PAX7_NOBOX

Gene Symbol Gene ID Gene Info
ENSG00000009709.7 paired box 7
ENSG00000106410.10 NOBOX oogenesis homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX7hg19_v2_chr1_+_18957500_18957623-0.321.7e-01Click!

Activity profile of PAX7_NOBOX motif

Sorted Z-values of PAX7_NOBOX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 1.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.3 1.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 0.5 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 2.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.1 0.3 GO:2000820 pathogenesis(GO:0009405) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 2.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.2 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 3.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289) insulin metabolic process(GO:1901142)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.6 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000275 cellular amide catabolic process(GO:0043605) regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.6 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0022405 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0060928 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.0 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0097196 Shu complex(GO:0097196)
0.2 2.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.6 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.9 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 0.6 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 0.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 0.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 3.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0035197 siRNA binding(GO:0035197)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.6 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0032934 sterol binding(GO:0032934)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane