ISMARA results: PAX7

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX7_NOBOX

Z-value: 1.31

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Transcription factors associated with PAX7_NOBOX

Gene Symbol	Gene ID	Gene Info
PAX7 Ensembl NCBI GeneCards UniProt	ENSG00000009709.7	paired box 7
NOBOX Ensembl NCBI GeneCards UniProt	ENSG00000106410.10	NOBOX oogenesis homeobox

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PAX7	hg19_v2_chr1_+_18957500_18957623	-0.32	1.7e-01	Click!

Activity profile of PAX7_NOBOX motif

Sorted Z-values of PAX7_NOBOX motif

No targets for PAX7_NOBOX

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	2.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	2.0	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.6	1.8	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1	1.7	GO:0043248	proteasome assembly(GO:0043248)
0.4	1.2	GO:0099558	maintenance of synapse structure(GO:0099558)
0.3	1.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	1.1	GO:0042246	tissue regeneration(GO:0042246)
0.2	1.0	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.1	0.9	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)

Showing 1 to 10 of 153 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.4	GO:0070469	respiratory chain(GO:0070469)
0.2	2.3	GO:0005577	fibrinogen complex(GO:0005577)
0.1	1.8	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.4	GO:0043083	synaptic cleft(GO:0043083)
0.0	1.4	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	1.1	GO:0097196	Shu complex(GO:0097196)
0.0	1.1	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.9	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.8	GO:0005854	nascent polypeptide-associated complex(GO:0005854)

Showing 1 to 10 of 59 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.0	1.9	GO:0051087	chaperone binding(GO:0051087)
0.4	1.8	GO:0019770	IgG receptor activity(GO:0019770)
0.1	1.7	GO:0070330	aromatase activity(GO:0070330)
0.0	1.7	GO:0005507	copper ion binding(GO:0005507)
0.0	1.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	1.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	1.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	1.0	GO:0032934	sterol binding(GO:0032934)
0.3	0.9	GO:0033961	cis-stilbene-oxide hydrolase activity(GO:0033961)

Showing 1 to 10 of 93 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
3.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
2.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.8	PID ARF 3PATHWAY	Arf1 pathway
0.8	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining

Showing 1 to 9 of 9 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	2.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	1.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	1.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.8	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription

Showing 1 to 10 of 30 entries

Results for PAX7_NOBOX

Z-value: 1.31

Motif logo

Transcription factors associated with PAX7_NOBOX

Activity-expression correlation:

Activity profile of PAX7_NOBOX motif

Sorted Z-values of PAX7_NOBOX motif

No targets for PAX7_NOBOX

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: