ISMARA results: PBX2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX2

Z-value: 0.41

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Transcription factors associated with PBX2

Gene Symbol	Gene ID	Gene Info
PBX2 Ensembl NCBI GeneCards UniProt	ENSG00000204304.7	PBX homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PBX2	hg19_v2_chr6_-_32157947_32157992	0.91	2.3e-08	Click!

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

No targets for PBX2

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.4	1.2	GO:0045081	negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.2	0.8	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.7	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0	0.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.5	GO:0015695	organic cation transport(GO:0015695)
0.1	0.2	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.2	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.2	GO:0051012	microtubule sliding(GO:0051012)

Showing 1 to 10 of 13 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.2	GO:1990075	periciliary membrane compartment(GO:1990075)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	1.2	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.8	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.7	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.5	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0019115	benzaldehyde dehydrogenase activity(GO:0019115)
0.0	0.1	GO:0047522	13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.8	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway

Showing 1 to 2 of 2 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation

Showing 1 to 2 of 2 entries

Results for PBX2

Z-value: 0.41

Motif logo

Transcription factors associated with PBX2

Activity-expression correlation:

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

No targets for PBX2

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: