ISMARA results: PLAG1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PLAG1

Z-value: 0.69

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Transcription factors associated with PLAG1

Gene Symbol	Gene ID	Gene Info
PLAG1 Ensembl NCBI GeneCards UniProt	ENSG00000181690.3	PLAG1 zinc finger

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PLAG1	hg19_v2_chr8_-_57123815_57123867	-0.63	2.7e-03	Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

No targets for PLAG1

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
0.3	1.0	GO:0035261	external genitalia morphogenesis(GO:0035261)
0.1	1.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	1.0	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.1	0.8	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.8	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	0.7	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.7	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1	0.7	GO:0021993	initiation of neural tube closure(GO:0021993)
0.2	0.6	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)

Showing 1 to 10 of 39 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	GO:0033643	host cell part(GO:0033643)
0.2	1.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.8	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.7	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.6	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.6	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.5	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.4	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)

Showing 1 to 10 of 18 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	GO:0032036	myosin heavy chain binding(GO:0032036)
0.3	1.0	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.1	1.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	1.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.8	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.8	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.8	GO:0030507	spectrin binding(GO:0030507)
0.2	0.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.1	0.7	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)

Showing 1 to 10 of 33 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
1.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.4	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation

Showing 1 to 10 of 10 entries

Results for PLAG1

Z-value: 0.69

Motif logo

Transcription factors associated with PLAG1

Activity-expression correlation:

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

No targets for PLAG1

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: