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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for POU4F1_POU4F3
Z-value: 1.81
Motif logo
Transcription factors associated with POU4F1_POU4F3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
POU4F1
|
ENSG00000152192.6 | POU class 4 homeobox 1 |
|
POU4F3
|
ENSG00000091010.4 | POU class 4 homeobox 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU4F1 | hg19_v2_chr13_-_79177673_79177701 | 0.89 | 1.9e-07 | Click! |
| POU4F3 | hg19_v2_chr5_+_145718587_145718607 | -0.12 | 6.3e-01 | Click! |
Activity profile of POU4F1_POU4F3 motif
Sorted Z-values of POU4F1_POU4F3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of POU4F1_POU4F3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.0 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.7 | 4.0 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.6 | 3.1 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 0.6 | 8.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.6 | 1.7 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.5 | 6.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.4 | 3.0 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 0.3 | 1.0 | GO:0071314 | cellular response to cocaine(GO:0071314) |
| 0.3 | 2.4 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.3 | 1.3 | GO:0048390 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.2 | 0.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.2 | 0.8 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.2 | 0.9 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701) |
| 0.1 | 0.9 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.1 | 0.8 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 1.5 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.1 | 1.5 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.4 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.1 | 0.4 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 4.0 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.1 | 3.9 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 0.3 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.1 | 1.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 1.6 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 2.0 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.1 | 0.5 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 2.2 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 0.6 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 0.5 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.1 | 0.5 | GO:0090292 | nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.3 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 1.5 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.1 | 0.4 | GO:0038112 | interleukin-8-mediated signaling pathway(GO:0038112) |
| 0.1 | 0.3 | GO:1901805 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
| 0.1 | 1.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 0.2 | GO:2000870 | regulation of progesterone secretion(GO:2000870) |
| 0.1 | 1.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.1 | 0.6 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.1 | 2.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.9 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.5 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.1 | 0.2 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 3.7 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.1 | 0.3 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.1 | 0.2 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.0 | 0.3 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.0 | 0.9 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.0 | 2.6 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.0 | 0.8 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.7 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 2.9 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.0 | 0.2 | GO:0042256 | mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.0 | 1.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.4 | GO:1900165 | negative regulation of interleukin-6 secretion(GO:1900165) |
| 0.0 | 5.9 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.0 | 1.0 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 0.3 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.3 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.0 | 0.7 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 1.0 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 1.7 | GO:0006506 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.1 | GO:0070898 | RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898) |
| 0.0 | 0.3 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.0 | 0.3 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 0.2 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.0 | 0.2 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.0 | 1.0 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.0 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.0 | 1.7 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 0.2 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.0 | 0.1 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.0 | 0.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 2.1 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 0.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 1.5 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 0.3 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 0.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.0 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.3 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.5 | GO:0007417 | central nervous system development(GO:0007417) |
| 0.0 | 1.0 | GO:0016445 | somatic diversification of immunoglobulins(GO:0016445) |
| 0.0 | 0.1 | GO:0098722 | asymmetric stem cell division(GO:0098722) |
| 0.0 | 0.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.9 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.3 | 1.0 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 0.3 | 2.8 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.2 | 6.0 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 2.2 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 1.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 0.8 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 0.9 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 0.9 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 0.5 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 2.5 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 1.1 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.8 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 1.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 1.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 0.6 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.1 | 0.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.1 | 0.6 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.7 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 1.7 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 1.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 3.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.0 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 0.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 3.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.5 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 4.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 1.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.2 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 0.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.7 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 1.5 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 2.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.3 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 2.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.0 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.9 | 2.6 | GO:0052857 | NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857) |
| 0.5 | 6.4 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.3 | 3.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.2 | 9.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.2 | 0.6 | GO:0010309 | acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309) |
| 0.2 | 5.9 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.2 | 3.9 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 2.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.5 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.1 | 0.3 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.1 | 0.3 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.1 | 3.8 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 1.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 0.7 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.1 | 0.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 1.0 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 0.2 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.1 | 0.8 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 0.4 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.1 | 0.3 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.1 | 1.6 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.1 | 0.3 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.0 | 2.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.5 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.3 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 1.4 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 3.0 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 0.2 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.0 | 1.0 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.1 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.0 | 0.2 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 2.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.4 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.3 | GO:0070915 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.0 | 0.9 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.1 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.0 | 0.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 1.2 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 0.2 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.1 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 6.5 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.3 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 1.0 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.3 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.1 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 5.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 3.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 1.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.5 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.9 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.9 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.4 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 3.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 6.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 7.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 6.7 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 3.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 2.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 2.0 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.9 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 1.7 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.0 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 0.9 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.7 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.0 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.6 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.8 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.2 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.3 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 2.0 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 1.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |