Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for POU5F1_POU2F3

Z-value: 1.28

Motif logo

Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F3hg19_v2_chr11_+_120107344_1201073510.587.6e-03Click!
POU5F1hg19_v2_chr6_-_31138439_311384750.223.5e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0036343 psychomotor behavior(GO:0036343)
0.5 2.2 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.4 2.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 2.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 1.7 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.3 1.3 GO:0035565 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020)
0.3 1.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.0 GO:0007412 axon target recognition(GO:0007412)
0.3 0.8 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 1.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 0.9 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.6 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 2.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.5 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.2 0.6 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.8 GO:0048391 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.6 GO:0002432 granuloma formation(GO:0002432)
0.1 0.6 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.6 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.4 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 1.7 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.5 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.4 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.5 GO:0036269 swimming behavior(GO:0036269)
0.1 0.8 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.4 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.6 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.7 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.7 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.4 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.8 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 1.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.5 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 1.5 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.1 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
0.1 1.0 GO:0042756 drinking behavior(GO:0042756)
0.1 0.4 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 2.5 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.1 0.2 GO:1990619 positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.4 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.2 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.5 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.2 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.6 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 0.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.3 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 1.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 2.0 GO:0007625 grooming behavior(GO:0007625)
0.1 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.2 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.1 0.3 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.2 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.7 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 4.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 1.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 4.4 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
0.0 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.4 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 1.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.5 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0070859 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 1.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.9 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.3 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.9 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.2 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 1.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0043654 complement activation, lectin pathway(GO:0001867) recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0000430 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.8 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.6 GO:0035094 response to nicotine(GO:0035094)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0014806 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900)
0.0 0.0 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.5 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.0 GO:0042435 serotonin biosynthetic process(GO:0042427) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.0 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0035993 deltoid tuberosity development(GO:0035993)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.3 GO:0071953 elastic fiber(GO:0071953)
0.1 1.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.6 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.1 1.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.7 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 3.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.6 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 1.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.5 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.2 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 0.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.7 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.5 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.4 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.1 1.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.3 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.4 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.5 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 1.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0043813 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 3.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID AURORA A PATHWAY Aurora A signaling
0.1 1.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 4.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1