avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
PRDM14 Links Ensembl NCBI GeneCards UniProt	ENSG00000147596.3	PR/SET domain 14

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PRDM14	hg19_v2_chr8_-_70983506_70983562	-0.43	5.5e-02	Click!

View svg image
View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.4	1.2	GO:0090427	activation of meiosis(GO:0090427)
0.3	1.5	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3	1.1	GO:0006550	isoleucine catabolic process(GO:0006550)
0.2	7.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.2	2.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.2	2.7	GO:0032306	regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.2	0.5	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.2	0.7	GO:0090119	vesicle-mediated cholesterol transport(GO:0090119)
0.1	2.2	GO:0002158	osteoclast proliferation(GO:0002158)
0.1	0.5	GO:0006601	creatine biosynthetic process(GO:0006601)
0.1	0.6	GO:0055018	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1	1.2	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	13.0	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.1	0.8	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.1	1.0	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	0.6	GO:0050893	sensory processing(GO:0050893)
0.1	0.9	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	1.3	GO:0051775	response to redox state(GO:0051775)
0.0	1.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.6	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.2	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.7	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	2.9	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.3	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.6	GO:0034389	lipid particle organization(GO:0034389)
0.0	1.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.3	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.9	GO:0007166	cell surface receptor signaling pathway(GO:0007166)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0005715	late recombination nodule(GO:0005715)
0.2	1.5	GO:0005638	lamin filament(GO:0005638)
0.1	0.6	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	0.7	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	1.0	GO:0001739	sex chromatin(GO:0001739)
0.1	2.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.9	GO:0000124	SAGA complex(GO:0000124)
0.0	0.6	GO:0034464	BBSome(GO:0034464)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	1.7	GO:0031526	brush border membrane(GO:0031526)
0.0	1.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.9	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	13.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0	2.9	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.7	2.1	GO:0004608	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3	2.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	2.7	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2	0.7	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2	2.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.2	1.1	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2	0.5	GO:0015068	amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1	0.4	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	0.7	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1	1.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.6	GO:0070700	BMP receptor binding(GO:0070700)
0.0	1.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.6	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.9	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	2.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins