ISMARA results: PRDM14

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM14

Z-value: 1.40

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Transcription factors associated with PRDM14

Gene Symbol	Gene ID	Gene Info
PRDM14 Ensembl NCBI GeneCards UniProt	ENSG00000147596.3	PR/SET domain 14

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PRDM14	hg19_v2_chr8_-_70983506_70983562	-0.43	5.5e-02	Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

No targets for PRDM14

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	13.0	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.2	7.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	2.9	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.2	2.7	GO:0032306	regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.1	2.2	GO:0002158	osteoclast proliferation(GO:0002158)
0.2	2.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.7	2.0	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.3	1.5	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1	1.3	GO:0051775	response to redox state(GO:0051775)
0.0	1.3	GO:0035329	hippo signaling(GO:0035329)

Showing 1 to 10 of 32 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.7	2.0	GO:0005715	late recombination nodule(GO:0005715)
0.0	1.7	GO:0031526	brush border membrane(GO:0031526)
0.2	1.5	GO:0005638	lamin filament(GO:0005638)
0.0	1.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.0	GO:0001739	sex chromatin(GO:0001739)
0.0	0.9	GO:0000124	SAGA complex(GO:0000124)
0.0	0.9	GO:0001772	immunological synapse(GO:0001772)
0.1	0.7	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	0.6	GO:0000333	telomerase catalytic core complex(GO:0000333)

Showing 1 to 10 of 13 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.4	13.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0	2.9	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.2	2.7	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3	2.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.7	2.1	GO:0004608	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2	2.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	1.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	1.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.2	1.1	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)

Showing 1 to 10 of 22 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
1.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	2.1	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	1.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Showing 1 to 10 of 12 entries

Results for PRDM14

Z-value: 1.40

Motif logo

Transcription factors associated with PRDM14

Activity-expression correlation:

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

No targets for PRDM14

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: