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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM4

Z-value: 0.80

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Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
ENSG00000110851.7 PR/SET domain 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_108154945-0.512.1e-02Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.6 1.7 GO:0061580 colon epithelial cell migration(GO:0061580)
0.4 1.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.3 3.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 2.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.1 0.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 3.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.4 1.7 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 6.8 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.8 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 1.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.2 0.5 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 1.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)