avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
PROX1
|
ENSG00000117707.11 | prospero homeobox 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
PROX1 | hg19_v2_chr1_+_214163033_214163073 | 0.39 | 9.3e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.4 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
0.2 | 0.8 | GO:0032796 | uropod organization(GO:0032796) |
0.2 | 0.6 | GO:0051413 | response to cortisone(GO:0051413) |
0.2 | 0.6 | GO:0006218 | uridine catabolic process(GO:0006218) |
0.2 | 0.5 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) |
0.1 | 1.4 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
0.1 | 0.6 | GO:0045399 | response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226) |
0.1 | 1.5 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
0.1 | 0.4 | GO:1900155 | regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) |
0.1 | 0.4 | GO:0072255 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
0.1 | 0.3 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
0.1 | 1.1 | GO:0044598 | polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
0.1 | 0.3 | GO:0009405 | pathogenesis(GO:0009405) |
0.1 | 0.8 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
0.1 | 0.6 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.1 | 0.3 | GO:1901143 | insulin catabolic process(GO:1901143) |
0.1 | 0.2 | GO:0034164 | negative regulation of toll-like receptor 9 signaling pathway(GO:0034164) |
0.1 | 0.3 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
0.1 | 0.7 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.1 | 0.5 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
0.1 | 0.3 | GO:0034093 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
0.0 | 0.9 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.0 | 0.4 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.7 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.5 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 0.3 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
0.0 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
0.0 | 0.2 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
0.0 | 0.2 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.5 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.0 | 0.4 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.0 | 0.3 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.0 | 0.1 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
0.0 | 0.1 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
0.0 | 0.3 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
0.0 | 0.1 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
0.0 | 0.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
0.0 | 0.2 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.0 | 0.4 | GO:0044126 | regulation of growth of symbiont in host(GO:0044126) |
0.0 | 0.2 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
0.0 | 0.7 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.3 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.0 | 0.7 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.0 | 0.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:2000053 | negative regulation of B cell differentiation(GO:0045578) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
0.0 | 0.1 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.0 | 0.3 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.0 | 0.2 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.0 | 0.2 | GO:0070269 | pyroptosis(GO:0070269) |
0.0 | 0.3 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.0 | 0.1 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
0.0 | 0.0 | GO:0002856 | negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) |
0.0 | 0.1 | GO:0015692 | lead ion transport(GO:0015692) |
0.0 | 0.1 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.0 | 0.1 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.0 | 0.1 | GO:0019046 | release from viral latency(GO:0019046) |
0.0 | 0.1 | GO:0034344 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
0.0 | 0.3 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.0 | 0.9 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
0.0 | 0.1 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.1 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
0.0 | 0.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.0 | 0.5 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.2 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
0.0 | 0.1 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
0.0 | 0.2 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.0 | 0.1 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.0 | 0.3 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
0.0 | 1.1 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
0.0 | 0.2 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.0 | 0.2 | GO:0086016 | AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) |
0.0 | 0.8 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
0.0 | 0.0 | GO:0030451 | regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957) |
0.0 | 0.1 | GO:0051012 | microtubule sliding(GO:0051012) |
0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.8 | GO:0097513 | myosin II filament(GO:0097513) |
0.1 | 1.4 | GO:0097025 | lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 0.6 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.1 | 0.2 | GO:1990716 | axonemal central apparatus(GO:1990716) |
0.0 | 0.7 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.2 | GO:0031592 | centrosomal corona(GO:0031592) |
0.0 | 0.8 | GO:0070938 | contractile ring(GO:0070938) |
0.0 | 0.3 | GO:0035061 | interchromatin granule(GO:0035061) |
0.0 | 0.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.0 | 1.5 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.7 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.2 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.0 | 0.2 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.5 | GO:0034706 | sodium channel complex(GO:0034706) |
0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 1.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) gamma-secretase complex(GO:0070765) |
0.0 | 0.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.3 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.0 | 0.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0003955 | NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025) |
0.2 | 1.4 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.2 | 1.5 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.1 | 0.7 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.6 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
0.1 | 1.4 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 0.5 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.1 | 0.3 | GO:0031626 | beta-endorphin binding(GO:0031626) |
0.1 | 1.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 0.6 | GO:0016936 | galactoside binding(GO:0016936) |
0.1 | 0.3 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
0.1 | 0.3 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.1 | 0.2 | GO:0030626 | U12 snRNA binding(GO:0030626) |
0.0 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.0 | 0.3 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.0 | 0.2 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.0 | 0.8 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
0.0 | 0.2 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
0.0 | 0.4 | GO:0008142 | oxysterol binding(GO:0008142) |
0.0 | 0.5 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.0 | 0.7 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
0.0 | 0.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
0.0 | 0.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 0.1 | GO:0033149 | FFAT motif binding(GO:0033149) |
0.0 | 0.2 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
0.0 | 0.6 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.0 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.2 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.0 | 0.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 0.9 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.0 | 0.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.0 | 0.4 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
0.0 | 1.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.1 | GO:0015087 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 0.2 | GO:0043515 | kinetochore binding(GO:0043515) |
0.0 | 0.1 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
0.0 | 1.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
0.0 | 0.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.1 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
0.0 | 0.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.0 | 0.6 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.0 | 0.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.0 | 0.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.0 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.0 | 0.2 | GO:0031014 | troponin T binding(GO:0031014) |
0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.0 | GO:0004877 | complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.5 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
0.0 | 0.3 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
0.0 | 1.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.6 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
0.0 | 0.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.4 | PID P53 REGULATION PATHWAY | p53 pathway |
0.0 | 0.7 | PID ATR PATHWAY | ATR signaling pathway |
0.0 | 1.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.4 | PID NECTIN PATHWAY | Nectin adhesion pathway |
0.0 | 0.6 | PID ATM PATHWAY | ATM pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.7 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.0 | 0.6 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.0 | 0.5 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 1.3 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.5 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
0.0 | 1.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
0.0 | 0.7 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
0.0 | 0.8 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.8 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.3 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 0.4 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.6 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |