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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for RAD21_SMC3
Z-value: 1.08
Motif logo
Transcription factors associated with RAD21_SMC3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RAD21
|
ENSG00000164754.8 | RAD21 cohesin complex component |
|
SMC3
|
ENSG00000108055.9 | structural maintenance of chromosomes 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RAD21 | hg19_v2_chr8_-_117886612_117886673 | -0.12 | 6.0e-01 | Click! |
| SMC3 | hg19_v2_chr10_+_112327425_112327516 | -0.12 | 6.3e-01 | Click! |
Activity profile of RAD21_SMC3 motif
Sorted Z-values of RAD21_SMC3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of RAD21_SMC3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.7 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.4 | 1.1 | GO:1901202 | negative regulation of extracellular matrix assembly(GO:1901202) |
| 0.4 | 1.1 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.3 | 1.9 | GO:1903412 | response to bile acid(GO:1903412) |
| 0.3 | 0.8 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) |
| 0.2 | 4.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.2 | 0.7 | GO:2000627 | regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) |
| 0.2 | 0.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.2 | 1.2 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.2 | 1.6 | GO:0000066 | mitochondrial ornithine transport(GO:0000066) |
| 0.2 | 0.6 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.2 | 1.6 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.2 | 0.7 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.2 | 0.8 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.2 | 0.9 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.1 | 1.3 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.1 | 1.7 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.1 | 0.6 | GO:0044691 | tooth eruption(GO:0044691) |
| 0.1 | 0.5 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.1 | 0.4 | GO:0010725 | regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) |
| 0.1 | 0.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.1 | 0.6 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.1 | 1.3 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 0.3 | GO:2000276 | negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
| 0.1 | 0.9 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.1 | 0.7 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 0.1 | 0.4 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.1 | 0.7 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.1 | 0.5 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.1 | 0.6 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.1 | 0.3 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349) |
| 0.1 | 1.5 | GO:0060263 | regulation of respiratory burst(GO:0060263) |
| 0.1 | 0.3 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.4 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 2.4 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.3 | GO:0090289 | regulation of osteoclast proliferation(GO:0090289) |
| 0.1 | 0.2 | GO:0002588 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) |
| 0.1 | 0.2 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.1 | 0.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.3 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.1 | 0.8 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.1 | 1.0 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 0.3 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.1 | 1.1 | GO:0030238 | male sex determination(GO:0030238) |
| 0.1 | 1.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.1 | 6.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.8 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.3 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 0.1 | 0.4 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.1 | 0.2 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.1 | 0.6 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 0.3 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.1 | 0.3 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 0.1 | GO:2001022 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of response to DNA damage stimulus(GO:2001022) |
| 0.1 | 0.5 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.1 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.3 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.1 | 1.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.1 | 0.1 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.1 | 0.4 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.0 | 0.5 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.0 | 1.1 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 2.0 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.0 | 1.1 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.0 | 1.0 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.0 | 0.2 | GO:0035712 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 0.0 | 0.3 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.0 | 0.6 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.0 | 0.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 0.3 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.0 | 0.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.0 | 0.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.0 | 0.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.0 | 0.3 | GO:1903899 | lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.0 | 0.1 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.0 | 1.8 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.0 | 0.7 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 0.0 | 0.7 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.1 | GO:1903027 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
| 0.0 | 0.7 | GO:0051608 | histamine transport(GO:0051608) |
| 0.0 | 0.1 | GO:0032827 | negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.0 | 0.9 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.9 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.0 | 0.1 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.0 | 0.1 | GO:0002428 | antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) |
| 0.0 | 0.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.2 | GO:1902715 | secretory granule localization(GO:0032252) positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.0 | 0.1 | GO:0006424 | glutamyl-tRNA aminoacylation(GO:0006424) |
| 0.0 | 0.6 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.0 | 0.2 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.0 | 0.6 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.2 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.0 | 0.4 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.0 | 0.1 | GO:0018282 | metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) |
| 0.0 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.4 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.0 | 0.5 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.0 | 0.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.1 | GO:2000721 | positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
| 0.0 | 0.6 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
| 0.0 | 0.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.0 | 0.7 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.0 | 0.2 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.0 | 0.2 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.0 | 0.8 | GO:0039702 | viral budding via host ESCRT complex(GO:0039702) |
| 0.0 | 0.4 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.3 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.0 | 0.3 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.0 | 0.2 | GO:0002249 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.0 | 0.3 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.2 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.0 | 0.4 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.2 | GO:0071316 | cellular response to nicotine(GO:0071316) |
| 0.0 | 0.7 | GO:0060065 | uterus development(GO:0060065) |
| 0.0 | 0.4 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.0 | 0.3 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 0.6 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.0 | 0.9 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.3 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.0 | 0.4 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.2 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.0 | 0.8 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.0 | 0.1 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.0 | 0.6 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 0.2 | GO:1902074 | response to salt(GO:1902074) |
| 0.0 | 0.2 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.0 | 0.2 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.0 | 0.1 | GO:0006272 | leading strand elongation(GO:0006272) |
| 0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.1 | GO:1900019 | embryonic genitalia morphogenesis(GO:0030538) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.0 | 0.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.0 | 0.3 | GO:0045821 | positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.0 | 0.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.0 | 0.2 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 0.1 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.0 | 0.1 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.0 | 1.6 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.6 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.0 | 0.8 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.1 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.0 | 1.3 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.9 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.0 | 0.5 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 0.0 | 0.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.2 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 0.8 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.0 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.0 | 0.3 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.0 | 0.1 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 1.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.1 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.0 | 0.1 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.0 | 0.1 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.0 | 0.3 | GO:0006506 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.5 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.2 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 0.2 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.0 | 0.0 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.0 | 0.0 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.0 | 0.3 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.1 | GO:0050868 | negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038) |
| 0.0 | 1.1 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 0.4 | GO:0051764 | actin crosslink formation(GO:0051764) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.0 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.2 | 0.7 | GO:0035101 | FACT complex(GO:0035101) |
| 0.2 | 1.6 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.2 | 2.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.2 | 0.6 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.1 | 0.6 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 0.4 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.1 | 1.0 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 0.7 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 1.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.8 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.1 | 0.8 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.8 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 0.8 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 0.7 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.1 | 0.6 | GO:0097361 | CIA complex(GO:0097361) |
| 0.1 | 1.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.3 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.1 | 0.5 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.1 | 1.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 1.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.2 | GO:0097134 | Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134) |
| 0.1 | 0.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 0.2 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.1 | 0.6 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.3 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.0 | 0.4 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.5 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 3.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.3 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.9 | GO:0032059 | bleb(GO:0032059) |
| 0.0 | 0.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.2 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.3 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 0.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.2 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.0 | 1.5 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.5 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 6.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.2 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.0 | 0.1 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.0 | 0.4 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 0.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.7 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.1 | GO:0042825 | TAP complex(GO:0042825) |
| 0.0 | 0.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.1 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.0 | 0.2 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.1 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.0 | 0.6 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.0 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.0 | 1.3 | GO:0016459 | myosin complex(GO:0016459) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.2 | 0.9 | GO:0001601 | peptide YY receptor activity(GO:0001601) |
| 0.2 | 1.6 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 0.2 | 0.7 | GO:0052825 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.2 | 1.4 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 0.6 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.2 | 0.6 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.2 | 1.3 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.2 | 1.8 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.2 | 0.7 | GO:0005019 | platelet-derived growth factor beta-receptor activity(GO:0005019) |
| 0.2 | 0.5 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.2 | 1.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.1 | 1.8 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.5 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.1 | 1.3 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.1 | 0.5 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.1 | 0.6 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.1 | 0.3 | GO:0048257 | 3'-flap endonuclease activity(GO:0048257) |
| 0.1 | 0.8 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.1 | 0.3 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.1 | 0.8 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 0.3 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.1 | 1.3 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.9 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 0.5 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.1 | 3.4 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.1 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.3 | GO:0031859 | platelet activating factor receptor binding(GO:0031859) |
| 0.1 | 0.3 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 0.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 1.6 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 0.4 | GO:0098625 | methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626) |
| 0.1 | 0.2 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.1 | 0.7 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.1 | 0.3 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.1 | 3.9 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.1 | 1.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.8 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.6 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 0.8 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.7 | GO:0005329 | dopamine transmembrane transporter activity(GO:0005329) |
| 0.1 | 1.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 1.5 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.8 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.1 | 0.8 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.5 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.3 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.0 | 0.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.8 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.2 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.0 | 0.2 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
| 0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.4 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.0 | 1.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 1.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 1.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.4 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.0 | 0.5 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 0.3 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.0 | 1.1 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.0 | 0.3 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 0.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.0 | 0.7 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.1 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.0 | 0.1 | GO:0004818 | glutamate-tRNA ligase activity(GO:0004818) |
| 0.0 | 0.6 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.1 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.0 | 0.2 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 0.0 | 0.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.0 | 0.5 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.1 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.0 | 1.1 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.1 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.0 | 0.4 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.0 | 0.1 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.0 | 1.1 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.0 | 1.3 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.7 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 0.4 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 0.1 | GO:0016530 | metallochaperone activity(GO:0016530) |
| 0.0 | 0.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.2 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.0 | 0.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.1 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.0 | 0.5 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.1 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 0.2 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923) |
| 0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 1.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.0 | 0.1 | GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.0 | 0.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 0.1 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.1 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.0 | 0.3 | GO:0031701 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.0 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.3 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.0 | 0.9 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.0 | 0.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.0 | 0.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.3 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 3.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.2 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.1 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 3.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.6 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 0.5 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.3 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 1.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 1.8 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.6 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 1.1 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.7 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.9 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.1 | 1.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 2.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 0.8 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 2.0 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 1.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 1.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 2.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.7 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 1.7 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.4 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 0.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.8 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 0.7 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.6 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 1.4 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.6 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.5 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.4 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 0.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.2 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 0.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.2 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.7 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |