ISMARA results: RBPJ

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RBPJ

Z-value: 0.28

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Transcription factors associated with RBPJ

Gene Symbol	Gene ID	Gene Info
RBPJ Ensembl NCBI GeneCards UniProt	ENSG00000168214.16	recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RBPJ	hg19_v2_chr4_+_26322987_26323031	0.55	1.1e-02	Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

No targets for RBPJ

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:1903567	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1	0.4	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0	0.4	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	0.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0	0.3	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.3	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.1	0.2	GO:0042245	RNA repair(GO:0042245)
0.0	0.2	GO:0010157	response to chlorate(GO:0010157)
0.0	0.2	GO:0060301	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)

Showing 1 to 10 of 26 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.0	0.3	GO:0070938	contractile ring(GO:0070938)
0.0	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0034515	proteasome storage granule(GO:0034515)
0.0	0.2	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)

Showing 1 to 10 of 11 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0031862	prostanoid receptor binding(GO:0031862)
0.0	0.2	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0005119	smoothened binding(GO:0005119)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.2	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)

Showing 1 to 10 of 15 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Showing 1 to 1 of 1 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions

Showing 1 to 2 of 2 entries

Results for RBPJ

Z-value: 0.28

Motif logo

Transcription factors associated with RBPJ

Activity-expression correlation:

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

No targets for RBPJ

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: