avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RFX3 Links Ensembl NCBI GeneCards UniProt	ENSG00000080298.11	regulatory factor X3
RFX2 Links Ensembl NCBI GeneCards UniProt	ENSG00000087903.8	regulatory factor X2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RFX2	hg19_v2_chr19_-_6110474_6110551	0.69	7.0e-04	Click!
RFX3	hg19_v2_chr9_-_3525968_3526016	-0.46	4.0e-02	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.9	GO:1901860	positive regulation of mitochondrial DNA metabolic process(GO:1901860)
2.2	6.6	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.0	5.9	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
1.8	7.3	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.7	5.1	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.7	5.0	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
1.5	4.6	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
1.3	5.3	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.3	5.3	GO:0002432	granuloma formation(GO:0002432)
1.2	3.7	GO:0070121	pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
1.1	8.0	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.1	3.3	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
1.1	12.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.1	9.8	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
1.1	5.4	GO:0032425	positive regulation of mismatch repair(GO:0032425)
1.1	4.3	GO:0034499	late endosome to Golgi transport(GO:0034499)
1.0	5.7	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.9	2.7	GO:0090340	positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.9	4.5	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.8	9.7	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.8	2.4	GO:0015680	intracellular copper ion transport(GO:0015680)
0.8	3.2	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
0.8	11.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.7	2.1	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.7	3.4	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.7	5.4	GO:0044375	regulation of peroxisome size(GO:0044375)
0.7	2.7	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.6	1.9	GO:0014016	neuroblast differentiation(GO:0014016)
0.6	1.2	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.6	3.6	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.6	2.4	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6	12.0	GO:0035641	locomotory exploration behavior(GO:0035641)
0.6	2.4	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.6	2.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.6	0.6	GO:0022900	electron transport chain(GO:0022900)
0.6	19.2	GO:0002021	response to dietary excess(GO:0002021)
0.6	5.6	GO:0045218	zonula adherens maintenance(GO:0045218)
0.6	2.8	GO:0098502	DNA dephosphorylation(GO:0098502)
0.6	3.3	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.5	5.3	GO:0070560	protein secretion by platelet(GO:0070560)
0.5	2.4	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.5	1.9	GO:0009236	cobalamin biosynthetic process(GO:0009236)
0.4	11.5	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.4	7.9	GO:0015886	heme transport(GO:0015886)
0.4	4.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4	3.6	GO:0018094	protein polyglycylation(GO:0018094)
0.4	2.7	GO:1903575	cornified envelope assembly(GO:1903575)
0.4	1.1	GO:0002663	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.4	3.6	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.3	1.9	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3	7.1	GO:0051014	actin filament severing(GO:0051014)
0.3	4.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	2.6	GO:0050957	equilibrioception(GO:0050957)
0.2	2.5	GO:0097338	response to clozapine(GO:0097338)
0.2	2.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.2	8.4	GO:0034389	lipid particle organization(GO:0034389)
0.2	2.3	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2	4.0	GO:0072520	seminiferous tubule development(GO:0072520)
0.2	2.3	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.2	1.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.2	1.6	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.2	1.6	GO:2000035	regulation of stem cell division(GO:2000035)
0.2	1.1	GO:0061009	common bile duct development(GO:0061009)
0.2	1.1	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2	3.7	GO:1901978	mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.2	1.8	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.2	8.7	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.2	1.1	GO:0036371	protein localization to T-tubule(GO:0036371)
0.2	1.9	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.2	4.2	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.2	0.6	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.2	2.8	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.2	0.6	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.2	7.8	GO:0048268	clathrin coat assembly(GO:0048268)
0.2	0.7	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	5.8	GO:0044458	motile cilium assembly(GO:0044458)
0.2	0.9	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2	1.7	GO:0048318	axial mesoderm development(GO:0048318)
0.2	1.3	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2	2.8	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	0.3	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2	2.0	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	1.9	GO:0005513	detection of calcium ion(GO:0005513)
0.2	1.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.2	1.7	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2	9.5	GO:0006298	mismatch repair(GO:0006298)
0.1	0.7	GO:0015862	uridine transport(GO:0015862)
0.1	1.0	GO:0051012	microtubule sliding(GO:0051012)
0.1	1.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.1	1.0	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	3.3	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	2.3	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	2.7	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.9	GO:0048511	rhythmic process(GO:0048511)
0.1	1.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	7.3	GO:0006739	NADP metabolic process(GO:0006739)
0.1	1.6	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	2.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	3.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	2.6	GO:0002115	store-operated calcium entry(GO:0002115)
0.1	0.4	GO:0061571	dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1	1.2	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1	2.2	GO:0000338	protein deneddylation(GO:0000338)
0.1	1.8	GO:0030238	male sex determination(GO:0030238)
0.1	10.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	2.4	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	4.2	GO:0018345	protein palmitoylation(GO:0018345)
0.1	5.5	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.7	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1	3.9	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	2.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	1.0	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.1	0.5	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.5	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1	15.4	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1	1.8	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	5.8	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.1	0.6	GO:0048549	endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1	0.6	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1	0.2	GO:0051040	regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1	1.3	GO:0061525	hindgut development(GO:0061525)
0.1	2.5	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	2.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	4.8	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.1	1.3	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.1	2.7	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1	0.6	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.2	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.1	0.8	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.3	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	4.8	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	1.3	GO:0030851	granulocyte differentiation(GO:0030851)
0.1	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.8	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	5.9	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	2.8	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.1	0.6	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.1	2.2	GO:0071801	regulation of podosome assembly(GO:0071801)
0.1	2.0	GO:0000042	protein targeting to Golgi(GO:0000042)
0.1	0.7	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	2.1	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.1	0.7	GO:0032264	IMP salvage(GO:0032264)
0.1	0.2	GO:0080154	regulation of fertilization(GO:0080154)
0.1	0.3	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549)
0.1	2.7	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.1	0.8	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.3	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	4.3	GO:0042246	tissue regeneration(GO:0042246)
0.1	2.3	GO:0045687	positive regulation of glial cell differentiation(GO:0045687)
0.1	0.9	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	6.9	GO:0070126	mitochondrial translational termination(GO:0070126)
0.1	3.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	3.2	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.5	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	5.6	GO:0046785	microtubule polymerization(GO:0046785)
0.1	0.2	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1	4.1	GO:0009060	aerobic respiration(GO:0009060)
0.1	1.2	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.1	0.5	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.6	GO:0043486	histone exchange(GO:0043486)
0.1	7.4	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.1	0.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.8	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	3.5	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	2.5	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.2	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	3.9	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	0.8	GO:0097320	membrane tubulation(GO:0097320)
0.0	1.1	GO:0048665	neuron fate specification(GO:0048665)
0.0	1.8	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.7	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.6	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	1.8	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.6	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.4	GO:0031344	regulation of cell projection organization(GO:0031344)
0.0	0.7	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	1.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.5	GO:0048670	regulation of collateral sprouting(GO:0048670) positive regulation of collateral sprouting(GO:0048672)
0.0	4.9	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	1.0	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	1.1	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.6	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	1.0	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	1.0	GO:0007035	vacuolar acidification(GO:0007035)
0.0	1.4	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.1	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.0	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.3	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.4	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.9	GO:0016578	histone deubiquitination(GO:0016578)
0.0	2.6	GO:0032418	lysosome localization(GO:0032418)
0.0	1.6	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.4	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.7	GO:0032526	response to retinoic acid(GO:0032526)
0.0	8.7	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	1.4	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.4	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.5	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	3.3	GO:0071426	ribonucleoprotein complex export from nucleus(GO:0071426)
0.0	0.7	GO:0021591	ventricular system development(GO:0021591)
0.0	2.1	GO:0042308	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.0	2.4	GO:0060996	dendritic spine development(GO:0060996)
0.0	0.9	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	1.6	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.5	GO:0001975	response to amphetamine(GO:0001975)
0.0	1.1	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.8	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.4	GO:0009749	response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0	0.7	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.3	GO:0008038	neuron recognition(GO:0008038)
0.0	0.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.4	GO:0007220	Notch receptor processing(GO:0007220)
0.0	1.1	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.8	GO:1903078	positive regulation of protein localization to plasma membrane(GO:1903078)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.8	GO:0016042	lipid catabolic process(GO:0016042)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	1.8	GO:0006338	chromatin remodeling(GO:0006338)
0.0	3.4	GO:0007411	axon guidance(GO:0007411)
0.0	1.5	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.2	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	1.7	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.2	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.3	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	1.3	GO:0030148	sphingolipid biosynthetic process(GO:0030148)
0.0	0.2	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.7	GO:1902636	kinociliary basal body(GO:1902636)
1.2	3.7	GO:0044609	DBIRD complex(GO:0044609)
1.2	7.3	GO:0097149	centralspindlin complex(GO:0097149)
1.1	4.6	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.9	19.4	GO:0036038	MKS complex(GO:0036038)
0.9	7.3	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.7	6.6	GO:1990812	growth cone filopodium(GO:1990812)
0.7	11.8	GO:0033010	paranodal junction(GO:0033010)
0.6	9.3	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.5	1.0	GO:1990716	axonemal central apparatus(GO:1990716)
0.4	1.3	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.4	7.1	GO:0097427	microtubule bundle(GO:0097427)
0.4	1.2	GO:0031021	interphase microtubule organizing center(GO:0031021)
0.4	3.2	GO:0043196	varicosity(GO:0043196)
0.4	7.1	GO:0032059	bleb(GO:0032059)
0.3	1.4	GO:1990423	RZZ complex(GO:1990423)
0.3	4.1	GO:0005577	fibrinogen complex(GO:0005577)
0.3	4.0	GO:0005828	kinetochore microtubule(GO:0005828)
0.3	4.8	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.3	5.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.3	4.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3	1.0	GO:0043291	RAVE complex(GO:0043291)
0.2	5.5	GO:0035102	PRC1 complex(GO:0035102)
0.2	3.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.2	0.9	GO:0031084	BLOC-2 complex(GO:0031084)
0.2	1.2	GO:0036156	inner dynein arm(GO:0036156)
0.2	5.6	GO:0005915	zonula adherens(GO:0005915)
0.2	3.0	GO:0034464	BBSome(GO:0034464)
0.2	1.0	GO:1990031	pinceau fiber(GO:1990031)
0.2	6.9	GO:0042101	T cell receptor complex(GO:0042101)
0.2	1.5	GO:0016272	prefoldin complex(GO:0016272)
0.2	5.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	4.4	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.2	1.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2	4.6	GO:0036020	endolysosome membrane(GO:0036020)
0.2	0.9	GO:0060077	inhibitory synapse(GO:0060077)
0.2	5.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	10.8	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	1.9	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	2.0	GO:0016342	catenin complex(GO:0016342)
0.1	2.0	GO:0042555	MCM complex(GO:0042555)
0.1	4.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	1.0	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.1	4.2	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.9	GO:1990635	proximal dendrite(GO:1990635)
0.1	0.8	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	3.7	GO:0002080	acrosomal membrane(GO:0002080)
0.1	11.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	1.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	1.0	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	3.1	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	3.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	2.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	2.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	1.7	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	8.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	9.9	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.1	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	18.7	GO:0005802	trans-Golgi network(GO:0005802)
0.1	4.7	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	0.5	GO:0089701	U2AF(GO:0089701)
0.1	0.8	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	4.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	1.3	GO:0001741	XY body(GO:0001741)
0.1	0.6	GO:0036128	CatSper complex(GO:0036128)
0.1	0.9	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.6	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	2.4	GO:0005921	gap junction(GO:0005921)
0.1	2.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	1.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	3.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0005726	perichromatin fibrils(GO:0005726) nuclear stress granule(GO:0097165)
0.0	1.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	6.7	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.6	GO:0032797	SMN complex(GO:0032797)
0.0	0.5	GO:0016589	NURF complex(GO:0016589)
0.0	3.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	2.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.6	GO:0097346	INO80-type complex(GO:0097346)
0.0	4.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	6.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	3.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	1.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	1.5	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.6	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	7.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	3.1	GO:0008021	synaptic vesicle(GO:0008021)
0.0	2.2	GO:0002102	podosome(GO:0002102)
0.0	1.3	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.6	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	12.8	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.3	GO:0005642	annulate lamellae(GO:0005642)
0.0	3.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.8	GO:0070822	Sin3-type complex(GO:0070822)
0.0	1.1	GO:0043034	costamere(GO:0043034)
0.0	2.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	1.5	GO:0031966	mitochondrial membrane(GO:0031966)
0.0	0.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	2.0	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.0	GO:0097224	sperm connecting piece(GO:0097224)
0.0	1.9	GO:0005938	cell cortex(GO:0005938)
0.0	2.0	GO:0001650	fibrillar center(GO:0001650)
0.0	1.3	GO:0005667	transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.7	GO:0052857	NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
1.5	9.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.5	4.5	GO:0050333	thiamin-triphosphatase activity(GO:0050333)
1.3	6.7	GO:0002046	opsin binding(GO:0002046)
1.0	3.0	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.9	5.4	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.9	2.7	GO:0001133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.8	3.3	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.8	7.7	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.7	3.6	GO:0070736	protein-glycine ligase activity, initiating(GO:0070736)
0.7	7.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.7	2.8	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.7	2.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.7	5.3	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.6	2.4	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.6	3.6	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.5	6.9	GO:1901612	cardiolipin binding(GO:1901612)
0.5	1.9	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.5	13.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.4	1.8	GO:0045131	pre-mRNA branch point binding(GO:0045131)
0.4	2.7	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.4	3.3	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.4	1.9	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4	12.9	GO:0000030	mannosyltransferase activity(GO:0000030)
0.3	5.6	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.3	1.9	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.3	4.8	GO:0015232	heme transporter activity(GO:0015232)
0.3	0.3	GO:0045142	triplex DNA binding(GO:0045142)
0.3	6.6	GO:0048156	tau protein binding(GO:0048156)
0.3	6.0	GO:0005522	profilin binding(GO:0005522)
0.3	3.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.3	4.5	GO:0045503	dynein light chain binding(GO:0045503)
0.3	2.8	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	1.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.2	0.6	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.2	0.6	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2	1.4	GO:0004127	cytidylate kinase activity(GO:0004127)
0.2	0.6	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.2	3.0	GO:0034452	dynactin binding(GO:0034452)
0.2	3.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	4.6	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2	2.0	GO:0004645	phosphorylase activity(GO:0004645)
0.2	3.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	3.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	2.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	1.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.2	0.5	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.2	3.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	0.6	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.2	0.6	GO:0032406	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2	0.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	5.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.1	7.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	1.3	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1	4.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	1.1	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	1.0	GO:0050815	phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1	0.4	GO:0097003	adipokinetic hormone receptor activity(GO:0097003)
0.1	4.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	1.5	GO:0046625	sphingolipid binding(GO:0046625)
0.1	2.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	16.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.0	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.7	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1	0.3	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.1	1.6	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	3.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	4.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	3.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1	1.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	1.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	5.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	3.9	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.5	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1	4.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	10.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.5	GO:0016417	S-acyltransferase activity(GO:0016417)
0.1	3.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.9	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	4.8	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	0.4	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	2.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	1.9	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.9	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	17.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.9	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	2.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	3.6	GO:0005504	fatty acid binding(GO:0005504)
0.1	0.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.7	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	4.3	GO:0030507	spectrin binding(GO:0030507)
0.1	1.3	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	5.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	1.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	1.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	2.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	1.9	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	1.0	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	0.8	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	2.0	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.2	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.1	1.4	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.5	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	1.6	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	2.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.3	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	1.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.4	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	4.7	GO:0003684	damaged DNA binding(GO:0003684)
0.0	11.0	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	5.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.8	GO:0005537	mannose binding(GO:0005537)
0.0	1.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0	1.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.9	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	1.2	GO:0071949	FAD binding(GO:0071949)
0.0	4.9	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	6.2	GO:0005496	steroid binding(GO:0005496)
0.0	0.1	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	1.5	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	4.9	GO:0003823	antigen binding(GO:0003823)
0.0	2.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	11.4	GO:0015631	tubulin binding(GO:0015631)
0.0	2.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	1.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.7	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	1.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	4.8	GO:0019902	phosphatase binding(GO:0019902)
0.0	1.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.6	GO:0051787	misfolded protein binding(GO:0051787)
0.0	5.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.1	GO:0019887	protein kinase regulator activity(GO:0019887)
0.0	0.7	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	2.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.9	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.8	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	9.3	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.9	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	1.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	11.0	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	15.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	11.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	3.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	3.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	11.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	8.1	PID AURORA B PATHWAY	Aurora B signaling
0.1	4.6	PID BARD1 PATHWAY	BARD1 signaling events
0.1	1.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	1.6	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	5.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	4.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.6	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.7	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	3.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	2.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.9	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.4	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	3.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	10.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5	5.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.3	13.5	REACTOME KINESINS	Genes involved in Kinesins
0.3	3.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	4.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	4.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	10.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	6.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	7.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	17.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	2.9	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	9.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	4.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	3.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	3.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	2.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	3.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	7.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	5.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	2.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	2.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	3.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	3.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.2	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.1	2.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	3.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	4.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	7.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	3.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.9	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	6.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	1.3	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	1.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	1.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	4.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	2.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	2.0	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	2.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	1.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	4.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes