ISMARA results: RFX5

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RFX5

Z-value: 0.86

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Transcription factors associated with RFX5

Gene Symbol	Gene ID	Gene Info
RFX5 Ensembl NCBI GeneCards UniProt	ENSG00000143390.13	regulatory factor X5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RFX5	hg19_v2_chr1_-_151319318_151319497	-0.83	5.8e-06	Click!

Activity profile of RFX5 motif

Sorted Z-values of RFX5 motif

No targets for RFX5

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.5	5.9	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0	3.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.9	3.4	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0	3.3	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	2.2	GO:0021510	spinal cord development(GO:0021510)
0.1	0.7	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.7	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.5	GO:0046967	cytosol to ER transport(GO:0046967)
0.0	0.5	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.4	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)

Showing 1 to 10 of 17 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.6	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	3.4	GO:0042627	chylomicron(GO:0042627)
0.2	3.3	GO:0036038	MKS complex(GO:0036038)
0.1	2.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.6	GO:0070652	HAUS complex(GO:0070652)
0.1	0.5	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.0	GO:0070703	inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)

Showing 1 to 10 of 10 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	3.6	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	3.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3	3.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	2.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.7	GO:0070736	protein-glycine ligase activity, initiating(GO:0070736)
0.1	0.5	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.3	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.2	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)

Showing 1 to 10 of 14 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	3.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Showing 1 to 4 of 4 entries

Results for RFX5

Z-value: 0.86

Motif logo

Transcription factors associated with RFX5

Activity-expression correlation:

Activity profile of RFX5 motif

Sorted Z-values of RFX5 motif

No targets for RFX5

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category: