ISMARA results: RHOXF1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RHOXF1

Z-value: 1.98

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Transcription factors associated with RHOXF1

Gene Symbol	Gene ID	Gene Info
RHOXF1 Ensembl NCBI GeneCards UniProt	ENSG00000101883.4	Rhox homeobox family member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RHOXF1	hg19_v2_chrX_-_119249819_119249847	0.08	7.5e-01	Click!

Activity profile of RHOXF1 motif

Sorted Z-values of RHOXF1 motif

No targets for RHOXF1

Network of associatons between targets according to the STRING database.

First level regulatory network of RHOXF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	12.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	11.5	GO:0018149	peptide cross-linking(GO:0018149)
0.7	5.9	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0	5.1	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.2	4.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.2	4.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.6	4.4	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.5	4.4	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.9	4.3	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	4.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)

Showing 1 to 10 of 394 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	18.5	GO:0001533	cornified envelope(GO:0001533)
0.3	9.4	GO:0030056	hemidesmosome(GO:0030056)
0.2	6.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	6.0	GO:0045095	keratin filament(GO:0045095)
0.7	5.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0	5.9	GO:0005604	basement membrane(GO:0005604)
0.2	4.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	4.4	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	4.3	GO:0035580	specific granule lumen(GO:0035580)
0.8	3.9	GO:0044393	microspike(GO:0044393)

Showing 1 to 10 of 154 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	12.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	7.0	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	5.4	GO:0055103	ligase regulator activity(GO:0055103)
0.0	5.3	GO:0002020	protease binding(GO:0002020)
0.0	5.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	4.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.6	4.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.3	4.3	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	4.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.8	4.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)

Showing 1 to 10 of 278 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	11.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	9.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	8.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	7.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	7.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	6.5	NABA COLLAGENS	Genes encoding collagen proteins
0.2	6.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	5.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	4.0	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1	3.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions

Showing 1 to 10 of 44 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	12.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.3	6.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	4.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	2.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	2.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	2.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	2.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins

Showing 1 to 10 of 68 entries

Results for RHOXF1

Z-value: 1.98

Motif logo

Transcription factors associated with RHOXF1

Activity-expression correlation:

Activity profile of RHOXF1 motif

Sorted Z-values of RHOXF1 motif

No targets for RHOXF1

Network of associatons between targets according to the STRING database.

First level regulatory network of RHOXF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: