Project
avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for RXRG
Z-value: 1.58
Motif logo
Transcription factors associated with RXRG
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RXRG
|
ENSG00000143171.8 | retinoid X receptor gamma |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RXRG | hg19_v2_chr1_-_165414414_165414433 | -0.48 | 3.1e-02 | Click! |
Activity profile of RXRG motif
Sorted Z-values of RXRG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of RXRG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 0.9 | 9.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.8 | 5.6 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.5 | 1.6 | GO:0060927 | Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929) |
| 0.5 | 2.7 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.4 | 1.3 | GO:0061743 | motor learning(GO:0061743) |
| 0.4 | 1.8 | GO:0071348 | cellular response to interleukin-11(GO:0071348) |
| 0.4 | 3.1 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.4 | 0.4 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 0.4 | 2.2 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.4 | 1.3 | GO:1901207 | regulation of heart looping(GO:1901207) |
| 0.4 | 1.3 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.3 | 1.9 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.3 | 1.0 | GO:0070904 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.3 | 0.9 | GO:0034963 | box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258) |
| 0.3 | 1.2 | GO:0098838 | reduced folate transmembrane transport(GO:0098838) |
| 0.3 | 1.2 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.3 | 1.2 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.3 | 1.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.3 | 1.1 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.3 | 0.8 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.2 | 1.5 | GO:1903588 | regulation of neural retina development(GO:0061074) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.2 | 0.7 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.2 | 3.6 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.2 | 1.2 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.2 | 0.9 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
| 0.2 | 1.8 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 1.0 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.2 | 0.6 | GO:0031446 | regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) |
| 0.2 | 1.8 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.2 | 0.9 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.2 | 1.0 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.2 | 1.6 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.2 | 0.6 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 0.2 | 1.4 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 1.6 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.2 | 2.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.2 | 0.6 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.2 | 0.6 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 0.2 | 0.8 | GO:1901536 | negative regulation of DNA demethylation(GO:1901536) |
| 0.1 | 1.0 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.1 | 0.8 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.1 | 1.2 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.1 | 1.1 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
| 0.1 | 2.5 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 1.0 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.6 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 0.1 | 0.6 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.5 | GO:0086043 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
| 0.1 | 0.7 | GO:0072240 | ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240) |
| 0.1 | 0.5 | GO:0019520 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
| 0.1 | 1.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.3 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 0.1 | 1.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.1 | 2.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.1 | 0.4 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.1 | 0.9 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.1 | 0.5 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 0.3 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 0.1 | 0.3 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 0.1 | 0.6 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.1 | 1.2 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.1 | 0.4 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.1 | 0.5 | GO:0044571 | [2Fe-2S] cluster assembly(GO:0044571) |
| 0.1 | 2.7 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.1 | 0.4 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 0.4 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 0.1 | 0.4 | GO:1901558 | response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
| 0.1 | 1.4 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
| 0.1 | 2.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 1.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.1 | 2.0 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.1 | 0.7 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.1 | 0.9 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 0.3 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245) |
| 0.1 | 0.3 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.1 | 0.6 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.1 | 0.3 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.1 | 0.3 | GO:0046379 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.1 | 0.8 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.1 | 0.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.1 | 0.7 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.1 | 1.1 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 0.1 | 1.7 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.5 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.1 | 0.2 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.1 | 0.9 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 0.2 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.1 | 1.0 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 0.3 | GO:0001834 | trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 1.8 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.1 | 1.6 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 1.8 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 0.7 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.1 | 0.5 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 0.1 | 0.6 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 0.1 | 0.5 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.1 | 0.7 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.1 | 0.6 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 0.4 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.1 | 0.2 | GO:0006288 | base-excision repair, DNA ligation(GO:0006288) |
| 0.1 | 0.2 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.1 | 0.9 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 2.3 | GO:0003416 | endochondral bone growth(GO:0003416) |
| 0.1 | 1.4 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.4 | GO:0000432 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) |
| 0.1 | 0.5 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 1.2 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.2 | GO:0002725 | negative regulation of T cell cytokine production(GO:0002725) |
| 0.1 | 0.9 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 0.3 | GO:0045588 | allantoin metabolic process(GO:0000255) positive regulation of gamma-delta T cell differentiation(GO:0045588) |
| 0.1 | 0.2 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.1 | 0.7 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.1 | 5.3 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.0 | 0.0 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.0 | 1.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.6 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.0 | 0.0 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.0 | 0.3 | GO:0036101 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.0 | 0.4 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.4 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.8 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.3 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.0 | 0.6 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.7 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
| 0.0 | 0.3 | GO:0033504 | floor plate development(GO:0033504) |
| 0.0 | 0.3 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.3 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.0 | 0.2 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.0 | 0.2 | GO:2000909 | regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909) |
| 0.0 | 0.4 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.0 | 0.9 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.0 | 0.7 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 0.2 | GO:0036309 | protein localization to M-band(GO:0036309) |
| 0.0 | 0.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.0 | 0.2 | GO:0015692 | lead ion transport(GO:0015692) |
| 0.0 | 1.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.3 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.0 | 0.1 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
| 0.0 | 0.1 | GO:1990654 | sebum secreting cell proliferation(GO:1990654) |
| 0.0 | 0.3 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 0.3 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.0 | 0.2 | GO:0070627 | ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.0 | 0.4 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.0 | 0.1 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 0.0 | 0.5 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.1 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.0 | 0.6 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.0 | 0.4 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 0.2 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.0 | 0.6 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.2 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.0 | 1.3 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.0 | 0.3 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.5 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.0 | 1.0 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.1 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.0 | 0.4 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 0.0 | 0.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.0 | 0.2 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.0 | 0.1 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.0 | 0.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.0 | 1.3 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 0.1 | GO:1904393 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.0 | 0.2 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.0 | 0.2 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 0.2 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.0 | 1.1 | GO:0001964 | startle response(GO:0001964) |
| 0.0 | 0.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.5 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.0 | 1.0 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.3 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.1 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.0 | 0.2 | GO:0035630 | bone mineralization involved in bone maturation(GO:0035630) |
| 0.0 | 0.4 | GO:0034349 | glial cell apoptotic process(GO:0034349) |
| 0.0 | 0.9 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.0 | 0.7 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 0.1 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.0 | 0.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.1 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.0 | 0.4 | GO:0039532 | negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) |
| 0.0 | 0.1 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.0 | 0.5 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
| 0.0 | 0.5 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 0.1 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.0 | 0.1 | GO:0034287 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 0.0 | 0.1 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.0 | 0.5 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 0.1 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.0 | 0.1 | GO:0033037 | polysaccharide localization(GO:0033037) |
| 0.0 | 0.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.8 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.2 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.7 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 0.0 | 0.0 | GO:0051177 | meiotic sister chromatid cohesion(GO:0051177) |
| 0.0 | 0.1 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.1 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.0 | 2.2 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 1.5 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 1.0 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 1.1 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 0.1 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.0 | 0.3 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.1 | GO:0034371 | chylomicron remodeling(GO:0034371) |
| 0.0 | 0.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.2 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.2 | GO:0015866 | ADP transport(GO:0015866) |
| 0.0 | 0.5 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.4 | GO:0097502 | mannosylation(GO:0097502) |
| 0.0 | 0.8 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.0 | 0.1 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.4 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 0.1 | GO:1900107 | hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107) |
| 0.0 | 0.4 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.1 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 0.3 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.4 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 0.1 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
| 0.0 | 0.5 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.0 | 0.2 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.0 | 1.2 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.1 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.0 | 0.3 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.2 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 0.0 | 0.0 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.0 | 0.3 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.3 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.0 | 0.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 0.1 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.0 | 0.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 9.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.6 | 1.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 1.6 | GO:1990742 | microvesicle(GO:1990742) |
| 0.4 | 3.6 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.3 | 0.9 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.3 | 1.8 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.3 | 1.2 | GO:0031523 | Myb complex(GO:0031523) |
| 0.3 | 2.3 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.3 | 3.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.2 | 3.0 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.2 | 2.1 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.2 | 1.0 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.2 | 2.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 1.7 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.2 | 0.9 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.1 | 0.7 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 0.1 | 1.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 1.8 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 1.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.4 | GO:0043257 | laminin-8 complex(GO:0043257) |
| 0.1 | 1.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.1 | 0.6 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.1 | 1.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.1 | 0.4 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.1 | 0.9 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 0.4 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 0.3 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 0.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.1 | 0.2 | GO:0070702 | inner mucus layer(GO:0070702) outer mucus layer(GO:0070703) |
| 0.1 | 1.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 0.4 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.1 | 0.6 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 1.6 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 4.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.7 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 0.1 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 0.0 | 0.9 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.4 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.2 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.0 | 1.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.6 | GO:0005719 | euchromatin(GO:0000791) nuclear euchromatin(GO:0005719) |
| 0.0 | 0.5 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.0 | 1.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.2 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.5 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 0.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 1.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.4 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.2 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.3 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.6 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 1.2 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.5 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.6 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.5 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.0 | 0.6 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 0.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 1.3 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.0 | 2.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 2.2 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 3.4 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.5 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 3.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.1 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 1.7 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 1.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.1 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 0.5 | 1.5 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
| 0.4 | 0.4 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.4 | 1.1 | GO:0086057 | voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057) |
| 0.4 | 1.4 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.3 | 2.7 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.3 | 0.7 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.3 | 1.6 | GO:0010736 | serum response element binding(GO:0010736) |
| 0.3 | 0.6 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.3 | 1.0 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.3 | 0.9 | GO:0036009 | protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259) |
| 0.3 | 1.2 | GO:0008518 | reduced folate carrier activity(GO:0008518) |
| 0.3 | 0.9 | GO:0047661 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.3 | 1.4 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.3 | 12.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.3 | 0.8 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.2 | 1.9 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 0.7 | GO:0080101 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.2 | 0.6 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.2 | 1.4 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.2 | 0.7 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.2 | 0.5 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 0.2 | 0.7 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.2 | 0.7 | GO:0072590 | N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) |
| 0.2 | 0.7 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.2 | 1.8 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.2 | 0.8 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.2 | 1.1 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.1 | 1.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 1.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.1 | 0.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 1.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 0.3 | GO:0097259 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.1 | 0.4 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.1 | 1.7 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 1.3 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.1 | 0.6 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.1 | 0.5 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.1 | 0.9 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 0.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.1 | 1.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 0.5 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.1 | 1.9 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.9 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 0.7 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.1 | 0.3 | GO:0097363 | protein O-GlcNAc transferase activity(GO:0097363) |
| 0.1 | 0.6 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.1 | 0.2 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 1.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.8 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.1 | 1.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 0.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.1 | 2.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.2 | GO:0052835 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.1 | 0.2 | GO:0072510 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 1.6 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 0.2 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.1 | 0.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 0.2 | GO:0051499 | D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500) |
| 0.1 | 0.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 1.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 2.5 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.1 | 0.2 | GO:0030617 | transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) |
| 0.1 | 2.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.1 | 0.4 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.8 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 1.0 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.5 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.0 | 0.6 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 1.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.3 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 0.2 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.7 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 0.2 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.0 | 0.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 1.3 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.2 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047) |
| 0.0 | 0.4 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.0 | 1.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.2 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.0 | 1.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 1.1 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.2 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.0 | 0.6 | GO:0048185 | activin binding(GO:0048185) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.3 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 0.7 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.9 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 1.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.6 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 1.1 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.7 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 0.1 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.0 | 0.4 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.0 | 0.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 4.7 | GO:0016853 | isomerase activity(GO:0016853) |
| 0.0 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.1 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.8 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 0.7 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.2 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.7 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.6 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.1 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.0 | 0.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) kainate selective glutamate receptor activity(GO:0015277) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.0 | 1.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.5 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.0 | 0.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.8 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 2.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.3 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.6 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.1 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.0 | 0.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.5 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 0.0 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.4 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.4 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 0.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.3 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.1 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.0 | 0.4 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.0 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.0 | 0.1 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.0 | 0.2 | GO:0031432 | titin binding(GO:0031432) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 4.8 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 1.4 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 10.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.3 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.7 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 3.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.1 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 0.4 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.9 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 2.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 1.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 3.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.3 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 1.2 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.4 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.3 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 1.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.4 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 1.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 0.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.2 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 0.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.8 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.2 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 1.2 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 0.8 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 0.5 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 3.3 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 2.1 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.1 | 4.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 3.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.9 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 3.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.3 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 1.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.3 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 1.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.9 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 2.3 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.0 | 7.7 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 3.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.2 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 1.5 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.6 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 2.5 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.9 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 1.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 1.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.9 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 2.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 1.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.0 | 0.7 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.1 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.4 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 0.4 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.4 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.6 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 0.1 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |