avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SIX4 Links Ensembl NCBI GeneCards UniProt	ENSG00000100625.8	SIX homeobox 4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SIX4	hg19_v2_chr14_-_61190754_61190852	0.27	2.5e-01	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	GO:0051673	membrane disruption in other organism(GO:0051673)
0.2	0.7	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.1	0.4	GO:0035349	coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1	0.5	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1	0.3	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1	0.2	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	0.9	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.3	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	0.5	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.1	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
0.0	1.3	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.4	GO:0031944	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0	0.6	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0042144	vacuole fusion, non-autophagic(GO:0042144)
0.0	0.5	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.3	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.0	0.2	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0	0.7	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0060623	pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0	0.3	GO:0071267	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0	0.1	GO:2000612	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0	0.1	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.0	1.4	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.0	GO:2000569	T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0	0.1	GO:0043686	co-translational protein modification(GO:0043686)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	1.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	1.1	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	GO:1990357	terminal web(GO:1990357)
0.0	0.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.5	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	1.1	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0036457	keratohyalin granule(GO:0036457)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2	0.9	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.7	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.4	GO:0080122	coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1	0.3	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1	1.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.5	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	1.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0046997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	3.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.5	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.5	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.4	GO:1990239	steroid hormone binding(GO:1990239)
0.0	1.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	1.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	1.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling