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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX1

Z-value: 0.57

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.3 SRY-box transcription factor 1

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

No targets for SOX1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 0.5 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0051541 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.3 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0071723 lipopolysaccharide receptor activity(GO:0001875) lipopeptide binding(GO:0071723)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis