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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX17

Z-value: 1.70

Motif logo

Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
ENSG00000164736.5 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg19_v2_chr8_+_55370487_553705030.483.3e-02Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0036343 psychomotor behavior(GO:0036343)
0.7 2.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 1.8 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.5 2.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.5 2.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.4 0.8 GO:1903524 positive regulation of vasoconstriction(GO:0045907) positive regulation of blood circulation(GO:1903524)
0.3 1.4 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.3 1.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.3 0.9 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.3 3.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.3 1.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 0.9 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.7 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.2 0.8 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.9 GO:1990523 bone regeneration(GO:1990523)
0.1 3.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.0 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 1.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 1.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.8 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.3 GO:1905069 allantois development(GO:1905069)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 0.4 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.2 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.6 GO:0045007 depurination(GO:0045007)
0.1 0.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 1.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.5 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 1.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.6 GO:0015824 proline transport(GO:0015824)
0.0 0.5 GO:0042262 DNA protection(GO:0042262)
0.0 0.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.9 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.2 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.4 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 4.2 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 4.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.5 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.5 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.4 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.7 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.4 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.6 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386) cellular response to mineralocorticoid stimulus(GO:0071389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.2 3.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 0.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.4 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 4.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 1.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 1.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 2.7 GO:0000781 chromosome, telomeric region(GO:0000781)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 1.6 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.5 1.5 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.3 1.0 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.3 0.9 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.3 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 3.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.7 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 1.3 GO:0032089 NACHT domain binding(GO:0032089)
0.2 0.8 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 0.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 1.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.6 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 1.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 1.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 1.1 GO:0010851 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.5 GO:0034584 piRNA binding(GO:0034584)
0.1 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.2 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.2 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.8 GO:0070330 aromatase activity(GO:0070330)
0.1 2.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 4.2 GO:0019843 rRNA binding(GO:0019843)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 2.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0043295 glutathione binding(GO:0043295)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.0 GO:0001848 complement binding(GO:0001848)
0.0 3.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 4.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 3.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling