ISMARA results: SOX17

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX17

Z-value: 1.70

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Transcription factors associated with SOX17

Gene Symbol	Gene ID	Gene Info
SOX17 Ensembl NCBI GeneCards UniProt	ENSG00000164736.5	SRY-box transcription factor 17

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX17	hg19_v2_chr8_+_55370487_55370503	0.48	3.3e-02	Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

No targets for SOX17

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.0	GO:0036343	psychomotor behavior(GO:0036343)
0.0	4.4	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	4.2	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1	3.9	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.3	3.4	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.5	2.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	2.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.7	2.0	GO:0051866	general adaptation syndrome(GO:0051866)
0.5	2.0	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0	1.9	GO:0007029	endoplasmic reticulum organization(GO:0007029)

Showing 1 to 10 of 128 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.8	GO:0005577	fibrinogen complex(GO:0005577)
0.1	4.2	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	3.4	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	2.7	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	1.9	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.9	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	1.6	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	1.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	1.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.3	GO:0035580	specific granule lumen(GO:0035580)

Showing 1 to 10 of 56 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.2	GO:0019843	rRNA binding(GO:0019843)
0.3	3.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.7	3.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	3.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	3.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	2.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	2.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	2.0	GO:0005178	integrin binding(GO:0005178)
0.1	1.8	GO:0070330	aromatase activity(GO:0070330)
0.0	1.8	GO:0030371	translation repressor activity(GO:0030371)

Showing 1 to 10 of 103 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
2.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.8	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
1.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.5	PID CONE PATHWAY	Visual signal transduction: Cones
0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	4.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	3.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	3.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	2.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.9	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	1.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	1.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Showing 1 to 10 of 30 entries

Results for SOX17

Z-value: 1.70

Motif logo

Transcription factors associated with SOX17

Activity-expression correlation:

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

No targets for SOX17

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: