ISMARA results: SOX30

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX30

Z-value: 0.81

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Transcription factors associated with SOX30

Gene Symbol	Gene ID	Gene Info
SOX30 Ensembl NCBI GeneCards UniProt	ENSG00000039600.6	SRY-box transcription factor 30

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX30	hg19_v2_chr5_-_157079428_157079452	-0.27	2.5e-01	Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

No targets for SOX30

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.6	GO:0072709	cellular response to sorbitol(GO:0072709)
0.2	3.2	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	2.8	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.4	1.8	GO:0060585	nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	1.5	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	1.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.3	1.1	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.3	1.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	1.0	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.8	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)

Showing 1 to 10 of 34 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	0.8	GO:0042382	paraspeckles(GO:0042382)
0.0	0.8	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	0.6	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.4	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.4	GO:0033269	internode region of axon(GO:0033269)
0.0	0.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)

Showing 1 to 10 of 12 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.2	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	2.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	2.8	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.4	1.8	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	1.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	1.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.2	1.1	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	0.6	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	0.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)

Showing 1 to 10 of 29 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	2.8	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.8	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway

Showing 1 to 5 of 5 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.6	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	3.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Showing 1 to 8 of 8 entries

Results for SOX30

Z-value: 0.81

Motif logo

Transcription factors associated with SOX30

Activity-expression correlation:

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

No targets for SOX30

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: