ISMARA results: SOX5

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX5

Z-value: 1.14

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Transcription factors associated with SOX5

Gene Symbol	Gene ID	Gene Info
SOX5 Ensembl NCBI GeneCards UniProt	ENSG00000134532.11	SRY-box transcription factor 5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX5	hg19_v2_chr12_-_23737534_23737550	0.14	5.4e-01	Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

No targets for SOX5

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2	1.9	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	1.9	GO:0048286	lung alveolus development(GO:0048286)
0.2	1.6	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2	1.4	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3	1.3	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	1.3	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	1.2	GO:0019075	virus maturation(GO:0019075)
0.1	1.2	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	1.2	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)

Showing 1 to 10 of 96 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.4	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	2.1	GO:0072562	blood microparticle(GO:0072562)
0.0	1.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.6	GO:0032420	stereocilium(GO:0032420)
0.0	1.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.6	GO:0005814	centriole(GO:0005814)
0.1	1.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	1.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	1.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	1.0	GO:0071564	npBAF complex(GO:0071564)

Showing 1 to 10 of 43 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.0	GO:0030165	PDZ domain binding(GO:0030165)
0.1	2.9	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	2.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	2.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	1.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	1.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	1.1	GO:0070698	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.0	1.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	1.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.0	GO:0004687	myosin light chain kinase activity(GO:0004687)

Showing 1 to 10 of 57 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.2	PID BMP PATHWAY	BMP receptor signaling
0.0	1.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	1.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Showing 1 to 10 of 14 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	2.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	2.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.7	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	1.7	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	1.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane

Showing 1 to 10 of 21 entries

Results for SOX5

Z-value: 1.14

Motif logo

Transcription factors associated with SOX5

Activity-expression correlation:

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

No targets for SOX5

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: