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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX9

Z-value: 1.99

Motif logo

Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
ENSG00000125398.5 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg19_v2_chr17_+_70117153_701171740.595.7e-03Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.8 7.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
1.4 8.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.8 4.7 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.8 2.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.7 4.9 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.7 2.0 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.7 3.3 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.6 3.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 2.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.6 1.8 GO:0008057 eye pigment granule organization(GO:0008057)
0.6 1.7 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 2.0 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.5 11.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4 6.3 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.4 15.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.4 2.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 1.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.4 1.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4 3.0 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4 1.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 2.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.3 1.4 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 2.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.3 1.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.3 5.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 0.9 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3 3.0 GO:0016584 nucleosome positioning(GO:0016584)
0.3 0.9 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.9 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.3 0.9 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.3 2.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 0.8 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 3.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 2.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 2.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 4.6 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 3.5 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 2.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.5 GO:1900222 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) negative regulation of beta-amyloid clearance(GO:1900222)
0.2 4.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.4 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2 1.9 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 2.0 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 3.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 0.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 3.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 0.5 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.2 3.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 2.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.9 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.4 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.6 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.1 GO:0060992 response to fungicide(GO:0060992) histone H3-K27 demethylation(GO:0071557)
0.1 2.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 2.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.9 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.0 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 1.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.6 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 3.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 5.0 GO:0097435 fibril organization(GO:0097435)
0.1 0.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 3.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.9 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.8 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.7 GO:0035093 proteasomal ubiquitin-independent protein catabolic process(GO:0010499) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.8 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.6 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 1.0 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 0.8 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 2.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.7 GO:0009597 detection of virus(GO:0009597)
0.1 1.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.8 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 1.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.9 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 3.4 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.2 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.1 GO:0098609 cell-cell adhesion(GO:0098609)
0.1 3.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.1 2.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.7 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 2.2 GO:0032620 interleukin-17 production(GO:0032620)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.9 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.5 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 1.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.8 GO:0030099 myeloid cell differentiation(GO:0030099)
0.0 0.8 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 2.9 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 1.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.6 GO:0072718 response to cisplatin(GO:0072718)
0.0 1.0 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 2.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 3.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.6 GO:0033127 regulation of histone phosphorylation(GO:0033127)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 2.6 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 5.3 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 3.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.4 GO:0007411 axon guidance(GO:0007411)
0.0 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.4 GO:0009214 cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214)
0.0 1.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 3.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 2.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 2.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 1.9 GO:0048678 response to axon injury(GO:0048678)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0042278 purine nucleoside metabolic process(GO:0042278)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.4 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.8 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.0 GO:1905037 autophagosome organization(GO:1905037)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0031213 RSF complex(GO:0031213)
0.7 2.2 GO:1990032 parallel fiber(GO:1990032)
0.6 1.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.5 16.4 GO:0030056 hemidesmosome(GO:0030056)
0.4 3.5 GO:1990357 terminal web(GO:1990357)
0.3 2.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 0.8 GO:0036457 keratohyalin granule(GO:0036457)
0.2 2.7 GO:0042382 paraspeckles(GO:0042382)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.2 5.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 5.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 5.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.5 GO:0097452 GAIT complex(GO:0097452)
0.2 15.4 GO:0045095 keratin filament(GO:0045095)
0.2 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 4.9 GO:0097386 glial cell projection(GO:0097386)
0.2 2.5 GO:0030478 actin cap(GO:0030478)
0.2 4.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.3 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.0 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.5 GO:0043219 lateral loop(GO:0043219)
0.1 2.4 GO:0043203 axon hillock(GO:0043203)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.9 GO:0016011 dystroglycan complex(GO:0016011)
0.1 5.7 GO:0002102 podosome(GO:0002102)
0.1 2.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0033391 chromatoid body(GO:0033391)
0.1 3.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.7 GO:1990752 microtubule end(GO:1990752)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 6.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 4.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0001939 female pronucleus(GO:0001939)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 11.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0072487 MSL complex(GO:0072487)
0.0 5.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 2.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 4.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 16.4 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 6.0 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 6.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0055100 adiponectin binding(GO:0055100)
1.0 6.9 GO:1990254 keratin filament binding(GO:1990254)
0.8 4.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.8 12.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.7 3.6 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.6 2.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 1.8 GO:0071633 dihydroceramidase activity(GO:0071633)
0.5 2.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 2.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.4 2.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.3 1.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.3 2.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 4.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 0.8 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 1.9 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 2.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 2.5 GO:0004111 creatine kinase activity(GO:0004111)
0.2 4.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 3.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 2.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.5 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2 3.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.7 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.7 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 1.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.5 GO:0031014 troponin T binding(GO:0031014)
0.1 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 3.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 2.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.0 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0010736 serum response element binding(GO:0010736)
0.1 2.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 2.8 GO:0070402 NADPH binding(GO:0070402)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.1 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 2.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 13.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 2.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 4.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 3.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 5.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.4 GO:0000339 RNA cap binding(GO:0000339)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.8 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 2.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 10.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.0 3.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0015288 porin activity(GO:0015288)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 3.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 2.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 3.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 1.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 17.9 NABA COLLAGENS Genes encoding collagen proteins
0.2 20.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 6.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 4.0 PID MYC PATHWAY C-MYC pathway
0.1 8.5 PID NOTCH PATHWAY Notch signaling pathway
0.1 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 5.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 3.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2 17.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 6.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 5.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 3.0 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling