avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SOX9 Links Ensembl NCBI GeneCards UniProt	ENSG00000125398.5	SRY-box transcription factor 9

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX9	hg19_v2_chr17_+_70117153_70117174	0.59	5.7e-03	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	12.4	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
1.8	7.1	GO:0051710	cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
1.4	8.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.8	4.7	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.8	2.3	GO:1990108	protein linear deubiquitination(GO:1990108)
0.7	4.9	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.7	2.0	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.7	3.3	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.6	3.7	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.6	2.4	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.6	1.8	GO:0008057	eye pigment granule organization(GO:0008057)
0.6	1.7	GO:0032289	central nervous system myelin formation(GO:0032289)
0.5	2.0	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.5	11.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4	6.3	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.4	15.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.4	1.3	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.4	2.2	GO:0043553	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4	1.3	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.4	1.3	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4	3.0	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4	1.8	GO:0090285	negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3	2.4	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.3	1.4	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3	2.1	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3	2.7	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952)
0.3	1.0	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
0.3	5.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3	0.9	GO:2000616	negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3	3.0	GO:0016584	nucleosome positioning(GO:0016584)
0.3	0.9	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3	0.9	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.3	0.9	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
0.3	2.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.3	0.8	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3	3.6	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	2.5	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.2	1.0	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.2	1.2	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2	2.4	GO:0044539	long-chain fatty acid import(GO:0044539)
0.2	4.6	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2	0.8	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.2	3.5	GO:0090168	Golgi reassembly(GO:0090168)
0.2	1.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.2	1.1	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.2	1.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.2	2.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2	0.5	GO:1900222	bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) negative regulation of beta-amyloid clearance(GO:1900222)
0.2	4.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	1.4	GO:0097466	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2	1.9	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.2	2.0	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2	3.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	0.5	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
0.2	1.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2	3.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	1.1	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2	0.5	GO:0072387	flavin adenine dinucleotide metabolic process(GO:0072387)
0.2	3.8	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	1.5	GO:1903764	regulation of potassium ion export across plasma membrane(GO:1903764)
0.1	2.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.9	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.4	GO:0035283	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.6	GO:0042823	pyridoxal phosphate biosynthetic process(GO:0042823)
0.1	1.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	1.1	GO:0060992	response to fungicide(GO:0060992) histone H3-K27 demethylation(GO:0071557)
0.1	2.5	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	0.4	GO:0042040	molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1	2.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.9	GO:0060056	mammary gland involution(GO:0060056)
0.1	1.4	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	1.0	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1	1.6	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.7	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.1	1.7	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	1.2	GO:0010265	SCF complex assembly(GO:0010265)
0.1	0.6	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1	0.2	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	1.4	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	1.7	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.3	GO:0032904	viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1	3.6	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1	5.0	GO:0097435	fibril organization(GO:0097435)
0.1	0.4	GO:0032072	plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1	3.6	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	0.9	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	0.8	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.7	GO:0035093	proteasomal ubiquitin-independent protein catabolic process(GO:0010499) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1	0.8	GO:0001714	endodermal cell fate specification(GO:0001714)
0.1	0.6	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	1.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.8	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	2.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.7	GO:0009597	detection of virus(GO:0009597)
0.1	1.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	0.6	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.1	0.8	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.3	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.1	0.2	GO:0031204	posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1	1.9	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.4	GO:0035026	leading edge cell differentiation(GO:0035026)
0.1	1.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	0.9	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.1	3.4	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.1	0.2	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1	1.1	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	2.0	GO:0035855	megakaryocyte development(GO:0035855)
0.1	1.1	GO:0098609	cell-cell adhesion(GO:0098609)
0.1	3.5	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.7	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.1	2.8	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	1.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	1.7	GO:0030336	negative regulation of cell migration(GO:0030336)
0.1	0.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.5	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	2.2	GO:0032620	interleukin-17 production(GO:0032620)
0.1	0.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	1.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.9	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.5	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1	0.5	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	1.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.9	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	1.0	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	1.0	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.8	GO:0030099	myeloid cell differentiation(GO:0030099)
0.0	0.8	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.5	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	2.9	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	1.5	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	1.4	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.6	GO:0072718	response to cisplatin(GO:0072718)
0.0	1.0	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.5	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	2.3	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	1.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.4	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	3.8	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.6	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.6	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.3	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.0	0.6	GO:0033127	regulation of histone phosphorylation(GO:0033127)
0.0	0.9	GO:0051639	actin filament network formation(GO:0051639)
0.0	2.6	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	1.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.6	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.5	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.4	GO:0051764	actin crosslink formation(GO:0051764)
0.0	5.3	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.4	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.3	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.8	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	3.3	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.4	GO:0007411	axon guidance(GO:0007411)
0.0	0.3	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.1	GO:0001579	medium-chain fatty acid transport(GO:0001579)
0.0	0.8	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	1.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	2.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.7	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	0.4	GO:0009214	cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214)
0.0	1.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	1.2	GO:0016486	peptide hormone processing(GO:0016486)
0.0	3.2	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.8	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.4	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.3	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.2	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	2.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0	2.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.4	GO:0021670	lateral ventricle development(GO:0021670)
0.0	1.9	GO:0048678	response to axon injury(GO:0048678)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	1.6	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.4	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	1.9	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.6	GO:0060325	face morphogenesis(GO:0060325)
0.0	1.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.6	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.7	GO:0042278	purine nucleoside metabolic process(GO:0042278)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.4	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0	0.8	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.0	0.5	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.8	GO:0018149	peptide cross-linking(GO:0018149)
0.0	1.1	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.2	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.0	1.1	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.7	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.6	GO:0035065	regulation of histone acetylation(GO:0035065)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.2	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	1.0	GO:1905037	autophagosome organization(GO:1905037)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.0	GO:0031213	RSF complex(GO:0031213)
0.7	2.2	GO:1990032	parallel fiber(GO:1990032)
0.6	1.8	GO:0005595	collagen type XII trimer(GO:0005595)
0.5	16.4	GO:0030056	hemidesmosome(GO:0030056)
0.4	3.5	GO:1990357	terminal web(GO:1990357)
0.3	2.5	GO:0042612	MHC class I protein complex(GO:0042612)
0.3	0.8	GO:0036457	keratohyalin granule(GO:0036457)
0.2	2.7	GO:0042382	paraspeckles(GO:0042382)
0.2	0.9	GO:0060187	cell pole(GO:0060187)
0.2	5.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2	0.8	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	5.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	5.0	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	1.5	GO:0097452	GAIT complex(GO:0097452)
0.2	15.4	GO:0045095	keratin filament(GO:0045095)
0.2	0.7	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.2	4.9	GO:0097386	glial cell projection(GO:0097386)
0.2	2.5	GO:0030478	actin cap(GO:0030478)
0.2	4.7	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	1.7	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	2.3	GO:0061700	GATOR2 complex(GO:0061700)
0.1	2.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	1.5	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.4	GO:0042585	germinal vesicle(GO:0042585)
0.1	1.0	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	1.5	GO:0043219	lateral loop(GO:0043219)
0.1	2.4	GO:0043203	axon hillock(GO:0043203)
0.1	0.5	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	1.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	2.1	GO:0031528	microvillus membrane(GO:0031528)
0.1	1.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	1.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.5	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.1	0.7	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.9	GO:0016011	dystroglycan complex(GO:0016011)
0.1	5.7	GO:0002102	podosome(GO:0002102)
0.1	2.9	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	3.8	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	0.7	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	1.0	GO:0033391	chromatoid body(GO:0033391)
0.1	3.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	2.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	1.7	GO:1990752	microtubule end(GO:1990752)
0.1	1.0	GO:0097427	microtubule bundle(GO:0097427)
0.1	6.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.7	GO:0016580	Sin3 complex(GO:0016580)
0.1	0.4	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	0.5	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	4.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.6	GO:0001939	female pronucleus(GO:0001939)
0.0	0.9	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	1.9	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	11.1	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.5	GO:0072487	MSL complex(GO:0072487)
0.0	5.7	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.8	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.7	GO:0032433	filopodium tip(GO:0032433)
0.0	0.8	GO:0071437	invadopodium(GO:0071437)
0.0	0.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	2.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0000322	storage vacuole(GO:0000322)
0.0	0.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	1.0	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	1.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	4.7	GO:0032432	actin filament bundle(GO:0032432)
0.0	1.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	1.9	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.5	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	1.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	16.4	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.3	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.5	GO:0036020	endolysosome membrane(GO:0036020)
0.0	2.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.4	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.0	0.7	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.8	GO:0005902	microvillus(GO:0005902)
0.0	0.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	2.9	GO:0072562	blood microparticle(GO:0072562)
0.0	0.9	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	6.0	GO:0005769	early endosome(GO:0005769)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	6.5	GO:0016607	nuclear speck(GO:0016607)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	6.3	GO:0055100	adiponectin binding(GO:0055100)
1.0	6.9	GO:1990254	keratin filament binding(GO:1990254)
0.8	4.9	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.8	12.4	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.7	3.6	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.6	2.5	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.6	1.8	GO:0071633	dihydroceramidase activity(GO:0071633)
0.5	2.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.5	2.3	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.4	2.7	GO:0032393	MHC class I receptor activity(GO:0032393)
0.3	1.3	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.3	2.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.3	4.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3	0.8	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3	1.9	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3	2.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.2	2.5	GO:0004111	creatine kinase activity(GO:0004111)
0.2	4.6	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	3.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.2	1.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.2	2.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.2	2.0	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2	0.5	GO:0001003	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2	3.7	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.6	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1	0.7	GO:0052839	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1	1.7	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.4	GO:0031862	prostanoid receptor binding(GO:0031862)
0.1	0.6	GO:0005199	structural constituent of cell wall(GO:0005199)
0.1	1.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	0.4	GO:0061599	molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1	0.5	GO:0031014	troponin T binding(GO:0031014)
0.1	1.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	3.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.4	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1	1.3	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	2.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	1.5	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.9	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.8	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	1.0	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.5	GO:0010736	serum response element binding(GO:0010736)
0.1	2.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	2.8	GO:0070402	NADPH binding(GO:0070402)
0.1	0.9	GO:0043237	laminin-1 binding(GO:0043237)
0.1	1.1	GO:0035005	lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.9	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	2.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	1.1	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.8	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.7	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	1.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	13.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.8	GO:0043426	MRF binding(GO:0043426)
0.1	2.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.5	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.1	4.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	2.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	1.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.9	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	3.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.3	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.1	0.6	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	1.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	1.9	GO:0031005	filamin binding(GO:0031005)
0.1	1.4	GO:0004707	MAP kinase activity(GO:0004707)
0.1	2.5	GO:0005523	tropomyosin binding(GO:0005523)
0.1	1.8	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	5.4	GO:0005080	protein kinase C binding(GO:0005080)
0.1	1.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	2.4	GO:0000339	RNA cap binding(GO:0000339)
0.1	5.0	GO:0070888	E-box binding(GO:0070888)
0.1	1.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.7	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	1.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	1.6	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.8	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	3.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.9	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.4	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	2.6	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	2.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	0.8	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	10.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	1.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.4	GO:0050815	phosphoserine binding(GO:0050815)
0.0	3.2	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	6.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	3.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	1.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.5	GO:0015288	porin activity(GO:0015288)
0.0	1.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	1.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	1.0	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.7	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	3.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	1.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	2.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	1.0	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	1.0	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.6	GO:0010181	FMN binding(GO:0010181)
0.0	2.1	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	3.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	2.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	1.0	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.7	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.8	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	1.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.5	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.6	GO:0097602	cullin family protein binding(GO:0097602)
0.0	1.4	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	2.7	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	1.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.6	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	1.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.5	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0035198	miRNA binding(GO:0035198)
0.0	1.4	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	2.2	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.5	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	1.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	1.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	1.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	1.6	GO:0005178	integrin binding(GO:0005178)
0.0	1.8	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	17.9	NABA COLLAGENS	Genes encoding collagen proteins
0.2	20.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	9.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	6.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	4.0	PID MYC PATHWAY	C-MYC pathway
0.1	8.5	PID NOTCH PATHWAY	Notch signaling pathway
0.1	0.9	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	5.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	5.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	1.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	2.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	2.5	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	2.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	3.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	2.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	3.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	2.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.8	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	2.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.0	3.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	0.7	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2	17.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	4.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	6.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	3.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.2	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	2.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	5.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	2.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	2.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	3.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.9	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	2.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	2.1	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling