avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SP100 Links Ensembl NCBI GeneCards UniProt	ENSG00000067066.12	SP100 nuclear antigen

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SP100	hg19_v2_chr2_+_231280908_231280945	0.12	6.1e-01	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0060382	regulation of DNA strand elongation(GO:0060382)
0.7	2.2	GO:0033488	cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.6	1.9	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.6	3.8	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.4	2.2	GO:0043335	protein unfolding(GO:0043335)
0.4	1.7	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.4	2.5	GO:0034421	post-translational protein acetylation(GO:0034421)
0.3	2.7	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3	1.3	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3	1.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.3	1.7	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.3	2.8	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.3	0.8	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3	1.1	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.3	0.8	GO:0006433	prolyl-tRNA aminoacylation(GO:0006433)
0.3	0.8	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2	1.7	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.2	0.7	GO:1904479	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.2	1.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	5.9	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.2	0.6	GO:0034059	response to anoxia(GO:0034059) positive regulation of penile erection(GO:0060406)
0.2	0.8	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.2	1.7	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2	0.8	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.2	2.8	GO:0001887	selenium compound metabolic process(GO:0001887)
0.2	1.2	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.2	0.6	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.2	0.6	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2	0.8	GO:0035350	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.2	2.3	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2	0.9	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.2	1.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	0.7	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2	2.0	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2	1.2	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2	0.7	GO:0006597	spermine biosynthetic process(GO:0006597)
0.2	3.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	1.2	GO:0046836	glycolipid transport(GO:0046836)
0.2	0.7	GO:0016598	protein arginylation(GO:0016598)
0.2	0.7	GO:0035627	ceramide transport(GO:0035627)
0.2	0.5	GO:1903452	regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.2	1.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	0.8	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.2	1.0	GO:0001927	exocyst assembly(GO:0001927)
0.2	1.9	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.2	0.6	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2	0.2	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.2	0.8	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1	0.7	GO:0070124	mitochondrial translational initiation(GO:0070124)
0.1	1.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	1.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.6	GO:0006408	snRNA export from nucleus(GO:0006408)
0.1	0.8	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	0.4	GO:1902771	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1	0.4	GO:0009405	pathogenesis(GO:0009405)
0.1	1.5	GO:0003350	pulmonary myocardium development(GO:0003350)
0.1	4.5	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	2.9	GO:0051382	kinetochore assembly(GO:0051382)
0.1	2.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	1.0	GO:1903826	arginine transmembrane transport(GO:1903826)
0.1	1.5	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.5	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.6	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.5	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.1	0.5	GO:1990927	negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1	0.4	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	0.5	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.1	0.6	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	1.7	GO:0015867	ATP transport(GO:0015867)
0.1	0.4	GO:0031456	glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1	1.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.6	GO:0060809	mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1	3.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1	0.7	GO:1903788	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1	1.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	1.6	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	0.6	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.6	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.1	0.3	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	1.8	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	1.3	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	1.3	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.5	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	1.7	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	1.0	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	1.0	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.7	GO:0070475	rRNA base methylation(GO:0070475) mRNA methylation(GO:0080009)
0.1	0.9	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.7	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.1	0.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.4	GO:0009213	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1	0.3	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	0.3	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.1	2.7	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.1	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.2	GO:1903568	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1	1.6	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.8	GO:1902570	protein localization to nucleolus(GO:1902570)
0.1	0.6	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.5	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	1.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	1.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.3	GO:0046110	xanthine metabolic process(GO:0046110)
0.1	1.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.1	0.5	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	1.4	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.1	0.5	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	1.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	0.6	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1	0.6	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1	0.5	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0032242	regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1	0.9	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	0.3	GO:2000672	cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1	1.6	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.5	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	1.6	GO:0097502	mannosylation(GO:0097502)
0.1	0.3	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.8	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.3	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1	0.2	GO:0021997	response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1	0.3	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	1.7	GO:0002021	response to dietary excess(GO:0002021)
0.1	0.8	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.3	GO:0009257	10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1	0.4	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.4	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1	1.8	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.6	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1	0.5	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.2	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0	0.3	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.8	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	1.6	GO:0042327	positive regulation of phosphorylation(GO:0042327)
0.0	0.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.2	GO:0006601	creatine biosynthetic process(GO:0006601)
0.0	0.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.6	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.3	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.3	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.8	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.5	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.4	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.6	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	6.0	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	1.9	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.7	GO:0010225	response to UV-C(GO:0010225)
0.0	0.2	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.6	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	1.6	GO:0060325	face morphogenesis(GO:0060325)
0.0	2.5	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
0.0	1.8	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.3	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.3	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.0	0.9	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.8	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.5	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.2	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.0	0.8	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.4	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.6	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	1.5	GO:0033344	cholesterol efflux(GO:0033344)
0.0	1.1	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.7	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	1.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.9	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.3	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	1.0	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.3	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	1.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.5	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.4	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.3	GO:0006983	ER overload response(GO:0006983)
0.0	1.2	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.0	0.7	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.6	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.0	1.8	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.7	GO:0006312	mitotic recombination(GO:0006312)
0.0	0.3	GO:0032808	lacrimal gland development(GO:0032808)
0.0	1.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.9	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:2000627	rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0	0.4	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.9	GO:0043243	positive regulation of protein complex disassembly(GO:0043243)
0.0	0.4	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.3	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0	0.2	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.3	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	1.0	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.4	GO:0016081	synaptic vesicle docking(GO:0016081) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0019085	early viral transcription(GO:0019085)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	1.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.4	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.4	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.2	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	0.4	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.3	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.1	GO:0051892	negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0	0.2	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0	1.2	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	1.0	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.5	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.9	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.5	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.6	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.8	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.9	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.7	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.3	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	1.0	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	1.1	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.9	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	1.1	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.0	0.3	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.5	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.5	GO:0048488	synaptic vesicle endocytosis(GO:0048488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.3	GO:1990423	RZZ complex(GO:1990423)
0.6	1.8	GO:0071821	FANCM-MHF complex(GO:0071821)
0.5	1.6	GO:0034455	t-UTP complex(GO:0034455)
0.3	1.8	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3	5.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.3	2.9	GO:0033503	HULC complex(GO:0033503)
0.3	1.4	GO:0097362	MCM8-MCM9 complex(GO:0097362)
0.3	0.8	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2	0.9	GO:0036284	tubulobulbar complex(GO:0036284)
0.2	1.8	GO:0030891	VCB complex(GO:0030891)
0.2	1.5	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	3.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.2	3.4	GO:0001741	XY body(GO:0001741)
0.2	1.6	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2	2.7	GO:0070187	telosome(GO:0070187)
0.2	2.3	GO:0042587	glycogen granule(GO:0042587)
0.2	1.7	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	5.3	GO:0000242	pericentriolar material(GO:0000242)
0.1	0.4	GO:0032783	ELL-EAF complex(GO:0032783)
0.1	1.8	GO:0071986	Ragulator complex(GO:0071986)
0.1	4.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	1.7	GO:0033269	internode region of axon(GO:0033269)
0.1	2.3	GO:0000124	SAGA complex(GO:0000124)
0.1	0.5	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.8	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.5	GO:0031523	Myb complex(GO:0031523)
0.1	0.5	GO:0031592	centrosomal corona(GO:0031592)
0.1	0.6	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.1	0.7	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	1.5	GO:0042555	MCM complex(GO:0042555)
0.1	1.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.7	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	0.5	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	1.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.5	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	1.1	GO:0005883	neurofilament(GO:0005883)
0.1	0.6	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.1	0.3	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	7.1	GO:0005871	kinesin complex(GO:0005871)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.1	2.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	0.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	1.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	1.9	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.1	0.3	GO:1990246	uniplex complex(GO:1990246)
0.1	1.1	GO:0016342	catenin complex(GO:0016342)
0.0	1.2	GO:0097342	ripoptosome(GO:0097342)
0.0	0.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.5	GO:0097255	R2TP complex(GO:0097255)
0.0	1.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.8	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.2	GO:0031213	RSF complex(GO:0031213)
0.0	0.7	GO:0045179	apical cortex(GO:0045179)
0.0	0.6	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.7	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	2.1	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	1.0	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0032002	interleukin-28 receptor complex(GO:0032002)
0.0	0.4	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.4	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	1.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	2.6	GO:0002102	podosome(GO:0002102)
0.0	0.7	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.9	GO:0030686	90S preribosome(GO:0030686)
0.0	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	1.2	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	2.0	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.4	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	3.2	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.3	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0	0.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	2.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.8	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.5	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.8	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	1.0	GO:0000145	exocyst(GO:0000145)
0.0	2.8	GO:0000776	kinetochore(GO:0000776)
0.0	2.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.3	GO:0031045	dense core granule(GO:0031045)
0.0	1.5	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.4	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0008398	sterol 14-demethylase activity(GO:0008398)
0.6	3.8	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.6	1.7	GO:0086057	voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.6	2.8	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.5	1.6	GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.5	1.9	GO:0004644	phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.5	2.3	GO:0050115	myosin-light-chain-phosphatase activity(GO:0050115)
0.5	2.7	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.5	1.4	GO:0019781	NEDD8 activating enzyme activity(GO:0019781)
0.4	1.7	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.4	1.5	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.4	1.1	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.3	2.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3	0.8	GO:0004827	proline-tRNA ligase activity(GO:0004827)
0.3	0.8	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3	0.8	GO:0001147	transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3	1.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	1.0	GO:0003896	DNA primase activity(GO:0003896)
0.2	0.7	GO:0016768	spermine synthase activity(GO:0016768)
0.2	0.7	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2	3.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	0.8	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.2	0.8	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.2	0.8	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2	2.3	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	2.2	GO:0030911	TPR domain binding(GO:0030911)
0.2	0.8	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	0.8	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.2	0.9	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	0.9	GO:0017089	glycolipid transporter activity(GO:0017089)
0.2	1.2	GO:0070404	NADH binding(GO:0070404)
0.2	0.9	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.2	0.7	GO:0015616	DNA translocase activity(GO:0015616)
0.2	0.7	GO:0004057	arginyltransferase activity(GO:0004057)
0.2	1.7	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.7	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.2	1.2	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.2	0.7	GO:0036033	mediator complex binding(GO:0036033)
0.2	0.6	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	1.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	2.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	1.1	GO:0004771	sterol esterase activity(GO:0004771)
0.1	1.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.5	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	0.5	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	1.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	0.3	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	1.0	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.1	1.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.6	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	1.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.5	GO:0004905	type I interferon receptor activity(GO:0004905)
0.1	1.4	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1	3.0	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	2.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.7	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.3	GO:0030626	U12 snRNA binding(GO:0030626)
0.1	0.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1	0.3	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1	0.8	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	3.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	1.9	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	1.1	GO:0089720	caspase binding(GO:0089720)
0.1	1.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	1.7	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.3	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.1	1.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.3	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.4	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.4	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	3.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	0.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.2	GO:0015068	amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1	0.2	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.1	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	0.6	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.3	GO:0032089	NACHT domain binding(GO:0032089)
0.0	0.4	GO:0045545	syndecan binding(GO:0045545)
0.0	1.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.6	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	1.9	GO:0005123	death receptor binding(GO:0005123)
0.0	0.4	GO:0043295	glutathione binding(GO:0043295)
0.0	1.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.6	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	2.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	1.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.8	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0000994	RNA polymerase III core binding(GO:0000994)
0.0	1.0	GO:0015643	toxic substance binding(GO:0015643)
0.0	5.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.2	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.9	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.5	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.7	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.6	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	1.3	GO:0001848	complement binding(GO:0001848)
0.0	0.4	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.0	1.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	1.0	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.6	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.4	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0005119	smoothened binding(GO:0005119)
0.0	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	1.2	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.9	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.0	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	1.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	1.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	1.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.7	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.5	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	1.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0071253	connexin binding(GO:0071253)
0.0	0.3	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	1.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.9	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.8	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.5	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	1.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.2	GO:0003774	motor activity(GO:0003774)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0047522	13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0	0.3	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0	0.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	1.7	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.7	GO:0019894	kinesin binding(GO:0019894)
0.0	1.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.0	1.8	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	11.1	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.3	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	2.4	GO:0004386	helicase activity(GO:0004386)
0.0	0.3	GO:0016859	peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0	0.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.5	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.0	GO:0097363	protein O-GlcNAc transferase activity(GO:0097363)
0.0	0.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	3.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	8.9	PID AURORA B PATHWAY	Aurora B signaling
0.1	0.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	4.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	2.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	2.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.6	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.4	PID MYC PATHWAY	C-MYC pathway
0.0	1.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.9	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.0	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.5	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.8	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	7.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.8	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	3.6	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	2.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	15.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	1.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	3.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	3.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.8	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	2.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.7	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	2.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.7	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	3.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	1.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.7	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.7	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation