ISMARA results: SP100

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SP100

Z-value: 2.49

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Transcription factors associated with SP100

Gene Symbol	Gene ID	Gene Info
SP100 Ensembl NCBI GeneCards UniProt	ENSG00000067066.12	SP100 nuclear antigen

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SP100	hg19_v2_chr2_+_231280908_231280945	0.12	6.1e-01	Click!

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

No targets for SP100

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.0	GO:0007062	sister chromatid cohesion(GO:0007062)
0.2	5.9	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	4.5	GO:0071539	protein localization to centrosome(GO:0071539)
0.6	3.8	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	3.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2	3.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	2.9	GO:0051382	kinetochore assembly(GO:0051382)
0.3	2.8	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2	2.8	GO:0001887	selenium compound metabolic process(GO:0001887)
0.9	2.7	GO:0060382	regulation of DNA strand elongation(GO:0060382)

Showing 1 to 10 of 247 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.1	GO:0005871	kinesin complex(GO:0005871)
0.3	5.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
1.3	5.3	GO:1990423	RZZ complex(GO:1990423)
0.2	5.3	GO:0000242	pericentriolar material(GO:0000242)
0.1	4.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	3.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.2	3.4	GO:0001741	XY body(GO:0001741)
0.0	3.2	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.3	2.9	GO:0033503	HULC complex(GO:0033503)
0.0	2.8	GO:0000776	kinetochore(GO:0000776)

Showing 1 to 10 of 108 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	11.1	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	5.6	GO:0003777	microtubule motor activity(GO:0003777)
0.6	3.8	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	3.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	3.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.2	3.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	3.0	GO:0034185	apolipoprotein binding(GO:0034185)
0.6	2.8	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.5	2.7	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	2.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)

Showing 1 to 10 of 182 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.9	PID AURORA B PATHWAY	Aurora B signaling
0.1	4.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	3.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	2.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	2.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	2.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	2.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network

Showing 1 to 10 of 31 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	15.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	7.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.8	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	3.6	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	3.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	3.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	3.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	2.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	2.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	2.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Showing 1 to 10 of 61 entries

Results for SP100

Z-value: 2.49

Motif logo

Transcription factors associated with SP100

Activity-expression correlation:

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

No targets for SP100

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: