avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
STAT6 Links Ensembl NCBI GeneCards UniProt	ENSG00000166888.6	signal transducer and activator of transcription 6

Gene	Promoter	Pearson corr. coef.	P-value	Plot
STAT6	hg19_v2_chr12_-_57504975_57505019	0.55	1.2e-02	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.2	1.3	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.2	0.7	GO:0042144	vacuole fusion, non-autophagic(GO:0042144)
0.2	0.5	GO:0070429	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1	0.6	GO:1904499	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1	0.9	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	1.1	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1	0.3	GO:0051714	positive regulation of cytolysis in other organism(GO:0051714)
0.1	0.9	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	0.3	GO:0086055	atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1	0.5	GO:0018032	protein amidation(GO:0018032)
0.1	0.6	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.3	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	0.8	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1	0.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.2	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.1	0.5	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.2	GO:0009236	cobalamin biosynthetic process(GO:0009236)
0.1	0.4	GO:0030578	PML body organization(GO:0030578)
0.1	0.2	GO:0044691	tooth eruption(GO:0044691)
0.0	0.1	GO:0098972	dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0	0.2	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.5	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.4	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.3	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.4	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.3	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.3	GO:0015866	ADP transport(GO:0015866)
0.0	0.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.1	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0	1.0	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0	0.2	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:2000691	regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.1	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.6	GO:0003016	respiratory system process(GO:0003016)
0.0	0.1	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0	0.1	GO:0070980	biphenyl catabolic process(GO:0070980)
0.0	0.1	GO:0015692	lead ion transport(GO:0015692)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:1990357	terminal web(GO:1990357)
0.1	0.7	GO:0033263	CORVET complex(GO:0033263)
0.1	0.3	GO:0031213	RSF complex(GO:0031213)
0.1	0.8	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.6	GO:0070369	Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.2	GO:0005584	collagen type I trimer(GO:0005584)
0.1	0.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:1990425	ryanodine receptor complex(GO:1990425)
0.0	1.3	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.3	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.8	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	1.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.9	GO:0001533	cornified envelope(GO:0001533)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0070826	paraferritin complex(GO:0070826)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	1.9	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.3	GO:0086078	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1	0.5	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1	0.3	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1	0.6	GO:0004359	glutaminase activity(GO:0004359)
0.1	0.3	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.1	0.9	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.2	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.0	0.2	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0	0.5	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	1.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0	0.3	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	1.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0032093	SAM domain binding(GO:0032093)
0.0	0.1	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	1.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.9	PID IL1 PATHWAY	IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling