ISMARA results: TAL1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TAL1

Z-value: 2.48

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Transcription factors associated with TAL1

Gene Symbol	Gene ID	Gene Info
TAL1 Ensembl NCBI GeneCards UniProt	ENSG00000162367.7	TAL bHLH transcription factor 1, erythroid differentiation factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TAL1	hg19_v2_chr1_-_47697387_47697457	0.50	2.5e-02	Click!

Activity profile of TAL1 motif

Sorted Z-values of TAL1 motif

No targets for TAL1

Network of associatons between targets according to the STRING database.

First level regulatory network of TAL1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.3	25.7	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.1	13.4	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	11.9	GO:0070125	mitochondrial translational elongation(GO:0070125)
1.2	9.7	GO:1902998	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.5	9.7	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2	9.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
1.0	8.1	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6	7.8	GO:0007144	female meiosis I(GO:0007144)
0.2	7.2	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
2.3	7.0	GO:0006059	hexitol metabolic process(GO:0006059)

Showing 1 to 10 of 1,058 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	25.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	19.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.8	13.4	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.1	11.4	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	10.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	8.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	7.4	GO:0008021	synaptic vesicle(GO:0008021)
0.1	7.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	7.2	GO:0072562	blood microparticle(GO:0072562)
0.0	6.2	GO:0031966	mitochondrial membrane(GO:0031966)

Showing 1 to 10 of 305 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	25.7	GO:0003735	structural constituent of ribosome(GO:0003735)
1.2	25.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3	10.3	GO:0051787	misfolded protein binding(GO:0051787)
0.3	9.9	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5	9.7	GO:0036374	glutathione hydrolase activity(GO:0036374)
1.0	9.4	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0	7.3	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.3	7.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6	6.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	6.7	GO:0019212	phosphatase inhibitor activity(GO:0019212)

Showing 1 to 10 of 658 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	12.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	10.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	10.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	7.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.4	5.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	5.6	PID BMP PATHWAY	BMP receptor signaling
0.2	5.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	3.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	3.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	2.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network

Showing 1 to 10 of 69 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	21.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.3	21.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	18.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	10.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.2	9.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	9.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.2	8.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	8.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3	8.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	8.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions

Showing 1 to 10 of 150 entries

Results for TAL1

Z-value: 2.48

Motif logo

Transcription factors associated with TAL1

Activity-expression correlation:

Activity profile of TAL1 motif

Sorted Z-values of TAL1 motif

No targets for TAL1

Network of associatons between targets according to the STRING database.

First level regulatory network of TAL1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: